HIV,
Conditions
Brief summary
The aim of the investigators study is to demonstrate in healthy subjects and a cohort of patients infected with HIV, the presence of miRNAs in circulating peripheral blood microparticles (MPs).
Interventions
BIOLOGICALBlood samples
Sponsors
Assistance Publique Hopitaux De Marseille
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
30 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Age of 40 +/-10 years * Seronegativity for the HIV 2 * Patients of the group A: seropositivity for the HIV 1 confirmed in ELISA and Western Blot for at least 2 years and having never received from antiretroviral treatment, with a viral plasmatique load \> 1000 copies / ml * Patients of the group B: seropositivity for the HIV 1 confirmed in ELISA and Western Blot for at least 2 years and under stable antiretroviral treatment for at least 6 months, with a viral load undetectable plasmatique (\< 40 copies / ml) * patients of the group C : Matching on the age (+/-3 years) to a patient * Be considered healthy by the Investigator after a clinical examination Seronegativity for the HIV 1 confirmed in ELISA the day of the taking
Exclusion criteria
group A et B * Age of \< 30 years and \> in 50 years * Seropositivity for the HIV 2 group C Seropositivity for the HIV 2 \- Be under medicinal treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NUMBER OF miRNAs | 2 YEARS |
Secondary
| Measure | Time frame |
|---|---|
| Demonstrate the presence of miRNAs in microparticles | 2 YEARS |
Countries
France
Outcome results
None listed