Oropharyngeal Neoplasms
Conditions
Brief summary
This clinical trial studies the intensity of adjuvant (helper) therapy required in p16 positive oropharynx cancer patients, who have had all known disease removed surgically by a minimally invasive approach, and who have extracapsular spread in their lymph nodes. Patients can consent to participate in either the randomized (physician chooses radiotherapy arm or radiotherapy & cisplatin arm) or non-randomized (patient chooses radiotherapy arm or radiotherapy & cisplatin arm) pathways. After the surgery, receive either radiation alone, or radiation and weekly cis-platinum during therapy. Patients are then followed for cancer, functional and quality of life outcomes.
Interventions
RADIATIONIntensity-modulated radiation therapy (IMRT)
DRUGCisplatin
Sponsors
The Foundation for Barnes-Jewish Hospital
Washington University School of Medicine
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient must have histologically confirmed p16 positive squamous cell carcinoma of the oropharynx (OPSCC). * Patient must have undergone transoral resection of their T1-4a oropharynx primary to a negative margin, and a neck dissection(s). * Patient's disease must be pathological N-stage positive. * Patient's disease must show extracapsular spread (ECS) in their nodal metastasis verified by central pathologist's review. * Patients with synchronous primaries are included. * Patients with unknown primaries are included if the diagnosis and resection of a primary site in the oropharynx is made from an endoscopic or robotic surgical procedure(s). * Patients with recent excisional node biopsies/neck dissections are included if material is evaluable for extracapsular spread. * Patient must be ≥ 21 years of age. * ECOG performance status ≤ 2 (Karnofsky ≥60%). * Patients must have normal organ and marrow function as defined below: * leukocytes ≥3,000/mcL * absolute neutrophil count ≥1,500/mcL * platelets ≥100,000/mcL * total bilirubin \<1.5 X upper normal institutional limit * AST(SGOT)/ALT(SGPT) ≤2.5 X institutional upper limit of normal * creatinine within normal institutional limits OR creatinine clearance ≥60 mL/min/1.73 m2 for patients with creatinine levels above institutional normal * Patient (or legally authorized representative) must be able to understand and willing to sign a written informed consent document.
Exclusion criteria
* Patient must not have pathologically N stage negative disease. * Patient must not have outside nodal tissue from previous neck biopsy/neck dissections in which ECS cannot be confirmed or denied. * Patient must not have a true unknown primary in which permanent section results are negative for malignancy in completely excised ipsilateral oropharyngeal tissue (palatine and lingual tonsil). * Patient must not have distant metastatic disease at presentation. * Patient must not have gross residual and/or microscopic disease present after surgery including re-resection(s), per the operative and pathology report. * Patient must not have transoral robotic surgery (TORS) for a T3 or T4 primary tumor. * Patient must not have a history of prior invasive malignancy (except non-melanomatous skin cancer) unless disease free for a minimum of 3 years; noninvasive cancers (for example, carcinoma in situ of the oral cavity, larynx, breast or cervix are all permissible) are permitted even if diagnosed and treated \< 3 years ago. * Patient must not have had previous systemic chemotherapy for the study cancer. (Note: prior chemotherapy for a different cancer is allowable). * Patient must not be receiving any other investigational agents. * Patient must not have had any prior radiotherapy to the region of the study cancer that would result in overlap of radiation therapy fields * Patient must not have any life-threatening comorbid illnesses e.g. stroke with major sequelae or myocardial infarction/ unstable angina within the preceding 3 months or psychiatric illness/social situations that would limit compliance with study requirements. * Patient must not be pregnant or breastfeeding. If a woman of childbearing potential, patient must agree to use medically acceptable forms of contraception. Both men and women and members of all races and ethnic groups are eligible for this trial.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of Participants With Disease-free Survival (DFS) | 1 year | — |
| Locoregional Control | Up to 2 years | Rate of patients with no recurrence at original oropharyngeal site or in the neck nodal basins. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of Complications/Acute Toxicity by Organ Class | Approximately 18 weeks | -Assessed by the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 4.0. |
| Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Baseline, 1 month, 6 months, 12 months, and 24 months | * Each item is scored on a 5 point Likert scale (strongly disagree, disagree, no opinion, agree, strongly agree). Strongly agree = 1, Disagree = 2, No opinion = 3, Agree = 4, and Strongly Agree = 5 * The lower the score the lower the quality of life |
| Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Baseline, 1 month, 12 months, and 24 months | * 25 questions to assess the frequency in which participants experience cognitive failures including forgetfulness, distractibility, and false triggering * Answers range from 0 = never to 4 = very often * The higher the score the worse the cognitive failures the participant has experienced |
| Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Baseline, 12 months, and 24 months | -The NDII consists of 10 questions; each with a 5 level ordinally scaled response option ranging from not at all to a lot. The response for each item is then scored from 1 to 5, with 5 denoting higher quality of life (Not at all) and 1 being the least (A lot). |
| Rate of Distant Metastasis | Up to 2 years | Assessed by biopsy or imaging-detected recurrent disease at sites away from the original primary and cervical zone. |
| Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Baseline, 1 month, and 12 months | * 11 item questionnaire to identify issues with hearing * Answers are yes = 4, sometimes = 2, and no = 0 * The higher the score the more issues the participant has with hearing |
| Change in Quality of Life as Measured by Scale of Subjective Total Taste Acuity | Baseline, 1 month, 6 months, and 12 months | * 1 question that asks about taste acuity * Answers are 0 = same taste acuity as before treatment; 1 = mild loss of taste acuity, but not inconvenient in daily life; moderate loss of taste acuity, and sometimes inconvenient in daily life; severe loss of taste acuity, and frequently inconvenient in daily life; and 4 = almost complete or complete loss of taste acuity * The higher the score the worse the participant's taste acuity |
| Change in Quality of Life as Measured by Speech Handicap Index | Baseline and 12 months | * 31 questions regarding participant's speech and the effects of speech on his/her life * The answers for the first 30 questions range from 0 = never to 4 = always and the answers for the 31st question ranges from 0 = excellent to bad = 4 * The higher the score the worse the participant's speech is affecting his/her life |
| Change in Quality of Life as Measured by EORTC QLQ-C30 | Baseline, 1 month, 6 months, 12 months, and 24 months | * 30 questions designed to assess the quality of life of cancer patients * The first 28 questions have answers that range from 1=not at all to 4 = very much. The higher score indicates a worse quality of life * The last 2 questions have answers that range from 1 = very poor to 7 = excellent. The higher score indicates a better quality of life |
| Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Baseline, 1 month, 6 months, 12 months, and 24 months | * It contains 8 questions regarding dryness either during feeding or in the unstimulated state. Participants rate each item from 0 to 10, where 10 indicates the maximum dryness or discomfort due to dryness. * The higher the score the worse the participant's xerostomia |
| Disease Specific Survival | 1 year | — |
Countries
United States
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Radiotherapy * Patients undergo postoperative IMRT once daily, 5 days a week, for 6 weeks. The prescribed radiotherapy dose will be 60 Gy in 2 Gy once-daily fraction size (total of 30 fractions).
* Patients can consent to participate in either the randomized (physician chooses radiotherapy arm or radiotherapy & cisplatin arm) or non-randomized (patient chooses radiotherapy arm or radiotherapy & cisplatin arm) pathways | 27 |
| Radiotherapy, Cisplatin * Patients undergo postoperative IMRT once daily, 5 days a week, for 6 weeks. The prescribed radiotherapy dose will be 60 Gy in 2 Gy once-daily fraction size (total of 30 fractions)
* Patients also receive cisplatin 40 mg/m2 IV on Days 1, 8, 15, 22, 29, and 36 of radiation therapy (6 doses for a total of 240 mg/m2).
* Patients can consent to participate in either the randomized (physician chooses radiotherapy arm or radiotherapy & cisplatin arm) or non-randomized (patient chooses radiotherapy arm or radiotherapy & cisplatin arm) pathways | 15 |
| Total | 42 |
Withdrawals & dropouts
| Period | Reason | FG000 | FG001 |
|---|---|---|---|
| Overall Study | Not eligible | 0 | 2 |
| Overall Study | Patient withdrew before completing all radiotherapy | 1 | 0 |
| Overall Study | Withdrawal by Subject | 0 | 2 |
Baseline characteristics
| Characteristic | Radiotherapy | Total | Radiotherapy, Cisplatin |
|---|---|---|---|
| Age, Continuous | 56 years | 56 years | 55 years |
| Ethnicity (NIH/OMB) Hispanic or Latino | 0 Participants | 0 Participants | 0 Participants |
| Ethnicity (NIH/OMB) Not Hispanic or Latino | 27 Participants | 42 Participants | 15 Participants |
| Ethnicity (NIH/OMB) Unknown or Not Reported | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) American Indian or Alaska Native | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) Asian | 0 Participants | 1 Participants | 1 Participants |
| Race (NIH/OMB) Black or African American | 1 Participants | 1 Participants | 0 Participants |
| Race (NIH/OMB) More than one race | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) Native Hawaiian or Other Pacific Islander | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) Unknown or Not Reported | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) White | 26 Participants | 40 Participants | 14 Participants |
| Region of Enrollment United States | 27 participants | 42 participants | 15 participants |
| Sex: Female, Male Female | 3 Participants | 6 Participants | 3 Participants |
| Sex: Female, Male Male | 24 Participants | 36 Participants | 12 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk |
|---|---|---|
| deaths Total, all-cause mortality | 1 / 27 | 0 / 11 |
| other Total, other adverse events | 26 / 27 | 10 / 11 |
| serious Total, serious adverse events | 0 / 27 | 1 / 11 |
Outcome results
Primary
Locoregional Control
Rate of patients with no recurrence at original oropharyngeal site or in the neck nodal basins.
Time frame: Up to 2 years
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Radiotherapy | Locoregional Control | 26 Participants |
| Radiotherapy, Cisplatin | Locoregional Control | 9 Participants |
Primary
Number of Participants With Disease-free Survival (DFS)
Time frame: 1 year
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Radiotherapy | Number of Participants With Disease-free Survival (DFS) | 24 Participants |
| Radiotherapy, Cisplatin | Number of Participants With Disease-free Survival (DFS) | 10 Participants |
Secondary
Change in Cognitive Function as Measured by Cognitive Failures Questionnaire
* 25 questions to assess the frequency in which participants experience cognitive failures including forgetfulness, distractibility, and false triggering * Answers range from 0 = never to 4 = very often * The higher the score the worse the cognitive failures the participant has experienced
Time frame: Baseline, 1 month, 12 months, and 24 months
Population: Some participants were not analyzed as the participants did not complete the questionnaires.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you say something and realize afterwards that it might be taken as insulting? | 1.0000000 score on a scale | Standard Deviation 1.0632191 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to see what you want in a supermarket (although it's there)? | 0.6250000 score on a scale | Standard Deviation 0.7696696 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you forget where you put something like a newspaper or a book? | 1.0416667 score on a scale | Standard Deviation 0.8064504 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to listen to people's names when you are meeting them? | 1.7083333 score on a scale | Standard Deviation 1.3014763 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you read something and find you haven't been thinking about it and must read it again? | 1.4166667 score on a scale | Standard Deviation 0.9743076 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget what you came to the shops to buy? | 0.8333333 score on a scale | Standard Deviation 0.8164966 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget appointments? | 0.5833333 score on a scale | Standard Deviation 0.9743076 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget why you went from one part of the house to the other? | 1.2083333 score on a scale | Standard Deviation 0.9770927 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you have trouble making up your mind? | 0.9583333 score on a scale | Standard Deviation 1.0826363 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find yourself suddenly wondering whether you've used a word correctly? | 0.5833333 score on a scale | Standard Deviation 0.7172815 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't quite remember something although it's on the tip of your tongue? | 1.4166667 score on a scale | Standard Deviation 0.9743076 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to hear people speaking to you when you are doing something else? | 1.3750000 score on a scale | Standard Deviation 1.3772215 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to notice signposts on the road? | 0.6666667 score on a scale | Standard Deviation 0.9168313 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget which way to turn on a road you know well but rarely use? | 0.4782609 score on a scale | Standard Deviation 0.9472239 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you lose your temper and regret it? | 0.9583333 score on a scale | Standard Deviation 1.0417029 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you start doing one thing at home and get distracted into doing something else (unintentionally)? | 1.2500000 score on a scale | Standard Deviation 1.1887151 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you leave important letters unanswered for days? | 0.6666667 score on a scale | Standard Deviation 1.0772203 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you confuse right and left when giving directions? | 0.3333333 score on a scale | Standard Deviation 0.8681147 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't think of anything to say? | 0.7916667 score on a scale | Standard Deviation 0.9315329 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget people's names? | 1.8333333 score on a scale | Standard Deviation 1.1671842 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you drop things? | 0.4583333 score on a scale | Standard Deviation 0.7790276 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you bump into people? | 0.2500000 score on a scale | Standard Deviation 0.5316095 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you daydream when you out to be listening to something? | 1.1250000 score on a scale | Standard Deviation 1.0347232 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you accidentally throw away the thing you want and keep what you meant to throw away? | 0.5416667 score on a scale | Standard Deviation 1.0623668 |
| Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget whether you've turned off a light or a fire or locked the door? | 0.9583333 score on a scale | Standard Deviation 0.9990938 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to notice signposts on the road? | 0.3636364 score on a scale | Standard Deviation 0.6741999 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget why you went from one part of the house to the other? | 1.0909091 score on a scale | Standard Deviation 0.9438798 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget what you came to the shops to buy? | 0.6363636 score on a scale | Standard Deviation 0.8090398 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you forget where you put something like a newspaper or a book? | 1.00000000 score on a scale | Standard Deviation 0.8944272 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you daydream when you out to be listening to something? | 1.2727273 score on a scale | Standard Deviation 1.00905 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to listen to people's names when you are meeting them? | 1.0909091 score on a scale | Standard Deviation 1.3003496 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you leave important letters unanswered for days? | 0.6363636 score on a scale | Standard Deviation 1.0269106 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you start doing one thing at home and get distracted into doing something else (unintentionally)? | 1.0909091 score on a scale | Standard Deviation 1.0444659 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you accidentally throw away the thing you want and keep what you meant to throw away? | 0.1818182 score on a scale | Standard Deviation 0.4045199 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget appointments? | 0.5454545 score on a scale | Standard Deviation 0.6875517 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you bump into people? | 0.1818182 score on a scale | Standard Deviation 0.4045199 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget which way to turn on a road you know well but rarely use? | 0.4545455 score on a scale | Standard Deviation 0.8201995 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you lose your temper and regret it? | 1.0000000 score on a scale | Standard Deviation 0.7745967 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you say something and realize afterwards that it might be taken as insulting? | 0.9090909 score on a scale | Standard Deviation 0.8312094 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you have trouble making up your mind? | 0.9090909 score on a scale | Standard Deviation 1.0444659 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't quite remember something although it's on the tip of your tongue? | 1.4545455 score on a scale | Standard Deviation 1.2135598 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you read something and find you haven't been thinking about it and must read it again? | 1.3636364 score on a scale | Standard Deviation 1.2060454 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you confuse right and left when giving directions? | 0.2727273 score on a scale | Standard Deviation 0.4670994 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find yourself suddenly wondering whether you've used a word correctly? | 0.6363636 score on a scale | Standard Deviation 0.6741999 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you drop things? | 0.8181818 score on a scale | Standard Deviation 0.6030227 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't think of anything to say? | 0.5454545 score on a scale | Standard Deviation 0.6875517 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget people's names? | 1.6363636 score on a scale | Standard Deviation 1.5015144 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to hear people speaking to you when you are doing something else? | 1.2727273 score on a scale | Standard Deviation 1.2720778 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget whether you've turned off a light or a fire or locked the door? | 0.6363636 score on a scale | Standard Deviation 0.6741999 |
| Radiotherapy, Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to see what you want in a supermarket (although it's there)? | 0.4545455 score on a scale | Standard Deviation 0.522233 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you read something and find you haven't been thinking about it and must read it again? | 1.5454545 score on a scale | Standard Deviation 1.0107646 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget which way to turn on a road you know well but rarely use? | 0.4090909 score on a scale | Standard Deviation 0.9591212 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you lose your temper and regret it? | 1.0909091 score on a scale | Standard Deviation 1.0649879 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find yourself suddenly wondering whether you've used a word correctly? | 0.7727273 score on a scale | Standard Deviation 1.0203556 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you leave important letters unanswered for days? | 1.0000000 score on a scale | Standard Deviation 1.0235326 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget what you came to the shops to buy? | 1.1363636 score on a scale | Standard Deviation 0.9902118 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget why you went from one part of the house to the other? | 1.2727273 score on a scale | Standard Deviation 1.1621744 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't quite remember something although it's on the tip of your tongue? | 1.8181818 score on a scale | Standard Deviation 0.8528029 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to notice signposts on the road? | 0.7272727 score on a scale | Standard Deviation 0.9847319 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't think of anything to say? | 0.8636364 score on a scale | Standard Deviation 1.1252705 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you start doing one thing at home and get distracted into doing something else (unintentionally)? | 1.5454545 score on a scale | Standard Deviation 1.1843131 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget people's names? | 1.8636364 score on a scale | Standard Deviation 1.355604 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you confuse right and left when giving directions? | 0.4545455 score on a scale | Standard Deviation 0.9116846 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you daydream when you out to be listening to something? | 1.1818182 score on a scale | Standard Deviation 1.0064726 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you bump into people? | 0.3636364 score on a scale | Standard Deviation 0.6579517 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you accidentally throw away the thing you want and keep what you meant to throw away? | 0.5454545 score on a scale | Standard Deviation 1.0107646 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget whether you've turned off a light or a fire or locked the door? | 0.8636364 score on a scale | Standard Deviation 1.1252705 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you drop things? | 0.8181818 score on a scale | Standard Deviation 1.0527227 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you forget where you put something like a newspaper or a book? | 1.1363636 score on a scale | Standard Deviation 1.0371873 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to listen to people's names when you are meeting them? | 1.8181818 score on a scale | Standard Deviation 1.0970247 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget appointments? | 0.7727273 score on a scale | Standard Deviation 1.1097755 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you have trouble making up your mind? | 1.0000000 score on a scale | Standard Deviation 1.1126973 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you say something and realize afterwards that it might be taken as insulting? | 1.0000000 score on a scale | Standard Deviation 1.1126973 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to see what you want in a supermarket (although it's there)? | 0.9090909 score on a scale | Standard Deviation 1.0649879 |
| 1 Month - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to hear people speaking to you when you are doing something else? | 1.4090909 score on a scale | Standard Deviation 1.0980108 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't quite remember something although it's on the tip of your tongue? | 1.2727273 score on a scale | Standard Deviation 0.904534 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find yourself suddenly wondering whether you've used a word correctly? | 0.6363636 score on a scale | Standard Deviation 0.8090398 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you read something and find you haven't been thinking about it and must read it again? | 1.2727273 score on a scale | Standard Deviation 0.7862454 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget why you went from one part of the house to the other? | 1.0000000 score on a scale | Standard Deviation 1 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to notice signposts on the road? | 0.5454545 score on a scale | Standard Deviation 0.6875517 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you confuse right and left when giving directions? | 0.2727273 score on a scale | Standard Deviation 0.6466698 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you bump into people? | 0.1818182 score on a scale | Standard Deviation 0.6030227 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget whether you've turned off a light or a fire or locked the door? | 0.6363636 score on a scale | Standard Deviation 0.6741999 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to listen to people's names when you are meeting them? | 1.0909091 score on a scale | Standard Deviation 1.0444659 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you say something and realize afterwards that it might be taken as insulting? | 0.8181818 score on a scale | Standard Deviation 0.6030227 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to hear people speaking to you when you are doing something else? | 1.0909091 score on a scale | Standard Deviation 0.700649 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you lose your temper and regret it? | 0.8181818 score on a scale | Standard Deviation 0.6030227 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you leave important letters unanswered for days? | 0.4545455 score on a scale | Standard Deviation 0.9341987 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget which way to turn on a road you know well but rarely use? | 0.5454545 score on a scale | Standard Deviation 0.9341987 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to see what you want in a supermarket (although it's there)? | 0.5454545 score on a scale | Standard Deviation 0.6875517 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you have trouble making up your mind? | 0.9090909 score on a scale | Standard Deviation 0.9438798 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget appointments? | 0.6363636 score on a scale | Standard Deviation 0.6741999 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you forget where you put something like a newspaper or a book? | 0.8181818 score on a scale | Standard Deviation 0.7507572 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you accidentally throw away the thing you want and keep what you meant to throw away? | 0.1818182 score on a scale | Standard Deviation 0.6030227 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you daydream when you out to be listening to something? | 0.9090909 score on a scale | Standard Deviation 0.8312094 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget people's names? | 1.6363636 score on a scale | Standard Deviation 1.1200649 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you start doing one thing at home and get distracted into doing something else (unintentionally)? | 1.0000000 score on a scale | Standard Deviation 0.7745967 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget what you came to the shops to buy? | 0.3636364 score on a scale | Standard Deviation 0.6741999 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you drop things? | 0.6363636 score on a scale | Standard Deviation 0.6741999 |
| 1 Month - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't think of anything to say? | 0.9090909 score on a scale | Standard Deviation 0.700649 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you daydream when you out to be listening to something? | 1.0000000 score on a scale | Standard Deviation 0.9258201 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to listen to people's names when you are meeting them? | 2.0000000 score on a scale | Standard Deviation 1.1952286 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you drop things? | 0.6666667 score on a scale | Standard Deviation 0.6172134 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget appointments? | 0.5333333 score on a scale | Standard Deviation 0.8338094 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you accidentally throw away the thing you want and keep what you meant to throw away? | 0.6666667 score on a scale | Standard Deviation 0.7237469 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to see what you want in a supermarket (although it's there)? | 1.0666667 score on a scale | Standard Deviation 1.0997835 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to notice signposts on the road? | 0.6666667 score on a scale | Standard Deviation 0.6172134 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you say something and realize afterwards that it might be taken as insulting? | 1.0666667 score on a scale | Standard Deviation 0.7988086 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget people's names? | 2.0666667 score on a scale | Standard Deviation 1.3345233 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget whether you've turned off a light or a fire or locked the door? | 1.1333333 score on a scale | Standard Deviation 1.0600988 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you leave important letters unanswered for days? | 0.7857143 score on a scale | Standard Deviation 0.9749613 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you forget where you put something like a newspaper or a book? | 1.4000000 score on a scale | Standard Deviation 0.910259 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you confuse right and left when giving directions? | 0.2666667 score on a scale | Standard Deviation 0.5936168 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you have trouble making up your mind? | 0.9333333 score on a scale | Standard Deviation 0.9611501 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget what you came to the shops to buy? | 1.2666667 score on a scale | Standard Deviation 1.3345233 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't think of anything to say? | 0.8000000 score on a scale | Standard Deviation 0.8618916 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you lose your temper and regret it? | 0.8666667 score on a scale | Standard Deviation 0.8338094 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to hear people speaking to you when you are doing something else? | 1.4000000 score on a scale | Standard Deviation 0.910259 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't quite remember something although it's on the tip of your tongue? | 1.7333333 score on a scale | Standard Deviation 1.0327956 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget which way to turn on a road you know well but rarely use? | 0.3333333 score on a scale | Standard Deviation 0.6172134 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you start doing one thing at home and get distracted into doing something else (unintentionally)? | 1.3333333 score on a scale | Standard Deviation 1.1126973 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget why you went from one part of the house to the other? | 1.333333 score on a scale | Standard Deviation 1.3451854 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you bump into people? | 0.4666667 score on a scale | Standard Deviation 0.7432234 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you read something and find you haven't been thinking about it and must read it again? | 1.4666667 score on a scale | Standard Deviation 0.9154754 |
| 6 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find yourself suddenly wondering whether you've used a word correctly? | 0.8000000 score on a scale | Standard Deviation 0.8618916 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to hear people speaking to you when you are doing something else? | 1.8333333 score on a scale | Standard Deviation 0.9831921 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you daydream when you out to be listening to something? | 0.8333333 score on a scale | Standard Deviation 1.1690452 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find yourself suddenly wondering whether you've used a word correctly? | 0.6666667 score on a scale | Standard Deviation 1.2110601 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget why you went from one part of the house to the other? | 1.5000000 score on a scale | Standard Deviation 0.83666 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you confuse right and left when giving directions? | 0.3333333 score on a scale | Standard Deviation 0.5163978 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you start doing one thing at home and get distracted into doing something else (unintentionally)? | 2.3333333 score on a scale | Standard Deviation 1.2110601 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget people's names? | 1.6666667 score on a scale | Standard Deviation 1.0327956 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you leave important letters unanswered for days? | 0.8333333 score on a scale | Standard Deviation 0.7527727 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to notice signposts on the road? | 0.8333333 score on a scale | Standard Deviation 0.7527727 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you lose your temper and regret it? | 0.8333333 score on a scale | Standard Deviation 0.7527727 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't think of anything to say? | 1.1666667 score on a scale | Standard Deviation 0.7527727 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you have trouble making up your mind? | 1.0000000 score on a scale | Standard Deviation 1.0954451 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you read something and find you haven't been thinking about it and must read it again? | 2.1666667 score on a scale | Standard Deviation 1.1690452 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to listen to people's names when you are meeting them? | 1.3333333 score on a scale | Standard Deviation 1.0327959 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget appointments? | 0.8333333 score on a scale | Standard Deviation 0.7527727 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget what you came to the shops to buy? | 1.1666667 score on a scale | Standard Deviation 0.9831921 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to see what you want in a supermarket (although it's there)? | 1.0000000 score on a scale | Standard Deviation 0.6324555 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget whether you've turned off a light or a fire or locked the door? | 1.3333333 score on a scale | Standard Deviation 0.5163978 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you drop things? | 1.3333333 score on a scale | Standard Deviation 1.0327956 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you forget where you put something like a newspaper or a book? | 1.3333333 score on a scale | Standard Deviation 0.5163978 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget which way to turn on a road you know well but rarely use? | 0.5000000 score on a scale | Standard Deviation 0.83666 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you bump into people? | 0.8333333 score on a scale | Standard Deviation 1.3291601 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you accidentally throw away the thing you want and keep what you meant to throw away? | 0.3333333 score on a scale | Standard Deviation 0.5163978 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you say something and realize afterwards that it might be taken as insulting? | 1.0000000 score on a scale | Standard Deviation 0.6324555 |
| 6 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't quite remember something although it's on the tip of your tongue? | 2.0000000 score on a scale | Standard Deviation 0.6324555 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to listen to people's names when you are meeting them? | 1.6250000 score on a scale | Standard Deviation 1.0246951 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to see what you want in a supermarket (although it's there)? | 0.8750000 score on a scale | Standard Deviation 0.7187953 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you say something and realize afterwards that it might be taken as insulting? | 1.2500000 score on a scale | Standard Deviation 1 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find yourself suddenly wondering whether you've used a word correctly? | 0.7500000 score on a scale | Standard Deviation 0.6831301 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you have trouble making up your mind? | 1.0625000 score on a scale | Standard Deviation 0.9287088 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget which way to turn on a road you know well but rarely use? | 0.3125000 score on a scale | Standard Deviation 0.4787136 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget appointments? | 0.6250000 score on a scale | Standard Deviation 0.6191392 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget whether you've turned off a light or a fire or locked the door? | 0.7333333 score on a scale | Standard Deviation 0.7037316 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you forget where you put something like a newspaper or a book? | 1.1250000 score on a scale | Standard Deviation 0.7187953 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you bump into people? | 0.3125000 score on a scale | Standard Deviation 0.4787136 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you drop things? | 1.0000000 score on a scale | Standard Deviation 0.8944272 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you accidentally throw away the thing you want and keep what you meant to throw away? | 0.6250000 score on a scale | Standard Deviation 0.7187953 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you confuse right and left when giving directions? | 0.3750000 score on a scale | Standard Deviation 0.6191392 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you daydream when you out to be listening to something? | 1.0000000 score on a scale | Standard Deviation 0.7302967 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget people's names? | 1.8125000 score on a scale | Standard Deviation 0.9105859 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to notice signposts on the road? | 0.6250000 score on a scale | Standard Deviation 0.6191392 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't think of anything to say? | 1.0000000 score on a scale | Standard Deviation 0.9660918 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you start doing one thing at home and get distracted into doing something else (unintentionally)? | 1.3125000 score on a scale | Standard Deviation 0.9464847 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget why you went from one part of the house to the other? | 1.4375000 score on a scale | Standard Deviation 0.8920949 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't quite remember something although it's on the tip of your tongue? | 1.6250000 score on a scale | Standard Deviation 0.6191392 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you read something and find you haven't been thinking about it and must read it again? | 1.5625000 score on a scale | Standard Deviation 0.7274384 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget what you came to the shops to buy? | 0.7500000 score on a scale | Standard Deviation 0.8563488 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you lose your temper and regret it? | 0.8125000 score on a scale | Standard Deviation 0.75 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you leave important letters unanswered for days? | 0.8125000 score on a scale | Standard Deviation 0.75 |
| 12 Months - Radiotherapy | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to hear people speaking to you when you are doing something else? | 1.4375000 score on a scale | Standard Deviation 1.0307764 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you drop things? | 0.8571429 score on a scale | Standard Deviation 0.6900656 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you confuse right and left when giving directions? | 0.5714286 score on a scale | Standard Deviation 0.7867958 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to see what you want in a supermarket (although it's there)? | 0.7142857 score on a scale | Standard Deviation 0.48795 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't quite remember something although it's on the tip of your tongue? | 1.5714286 score on a scale | Standard Deviation 1.3972763 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you accidentally throw away the thing you want and keep what you meant to throw away? | 0.5714286 score on a scale | Standard Deviation 0.7867958 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you read something and find you haven't been thinking about it and must read it again? | 1.5714286 score on a scale | Standard Deviation 1.1338934 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to hear people speaking to you when you are doing something else? | 1.5714286 score on a scale | Standard Deviation 0.9759001 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you bump into people? | 0.5714286 score on a scale | Standard Deviation 0.9759001 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you forget where you put something like a newspaper or a book? | 1.5714286 score on a scale | Standard Deviation 1.3972763 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget appointments? | 1.0000000 score on a scale | Standard Deviation 1.1547005 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget which way to turn on a road you know well but rarely use? | 0.2857143 score on a scale | Standard Deviation 0.48795 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget what you came to the shops to buy? | 0.7142857 score on a scale | Standard Deviation 0.48795 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you lose your temper and regret it? | 1.4285714 score on a scale | Standard Deviation 1.272418 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you can't think of anything to say? | 1.0000000 score on a scale | Standard Deviation 1 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you have trouble making up your mind? | 1.1428571 score on a scale | Standard Deviation 1.2149858 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to listen to people's names when you are meeting them? | 1.4285714 score on a scale | Standard Deviation 1.272418 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find yourself suddenly wondering whether you've used a word correctly? | 0.8571429 score on a scale | Standard Deviation 0.8997354 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget people's names? | 1.8571429 score on a scale | Standard Deviation 1.3451854 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you fail to notice signposts on the road? | 0.8571429 score on a scale | Standard Deviation 1.069045 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you say something and realize afterwards that it might be taken as insulting? | 0.8571429 score on a scale | Standard Deviation 1.4638501 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you start doing one thing at home and get distracted into doing something else (unintentionally)? | 1.4285714 score on a scale | Standard Deviation 1.5118579 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget why you went from one part of the house to the other? | 1.4285714 score on a scale | Standard Deviation 1.272418 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you leave important letters unanswered for days? | 1.0000000 score on a scale | Standard Deviation 1.1547005 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you daydream when you out to be listening to something? | 0.8571429 score on a scale | Standard Deviation 1.069045 |
| 12 Months - Radiotherapy + Cisplatin | Change in Cognitive Function as Measured by Cognitive Failures Questionnaire | Do you find you forget whether you've turned off a light or a fire or locked the door? | 1.2857143 score on a scale | Standard Deviation 0.9511897 |
Secondary
Change in Hearing as Measured by Hearing Handicap Inventory - Adult
* 11 item questionnaire to identify issues with hearing * Answers are yes = 4, sometimes = 2, and no = 0 * The higher the score the more issues the participant has with hearing
Time frame: Baseline, 1 month, and 12 months
Population: Some participants were not analyzed as the participants did not complete the questionnaires.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you feel handicapped by a hearing problem? | 0.1250000 score on a scale | Standard Deviation 0.4484272 |
| Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to have argments with family members? | 0.2500000 score on a scale | Standard Deviation 0.6756639 |
| Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when listening to TV or radio? | 0.3750000 score on a scale | Standard Deviation 0.7109364 |
| Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to feel frustrated when talking to members of your family? | 0.1250000 score on a scale | Standard Deviation 0.4484272 |
| Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to attend religious services less often than you would like? | 0.0416667 score on a scale | Standard Deviation 0.2041241 |
| Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to feel embarrassed when you meet new people? | 0.2500000 score on a scale | Standard Deviation 0.6079188 |
| Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when in a restaurant with relatives or friends? | 0.2173913 score on a scale | Standard Deviation 0.5997364 |
| Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you have difficulty hearing or understanding co-workers or clients or customers? | 0.5000000 score on a scale | Standard Deviation 0.8340577 |
| Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty in the movies or in the theater? | 0.1666667 score on a scale | Standard Deviation 0.4815434 |
| Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when visiting friends or relatives or neighbors? | 0.3333333 score on a scale | Standard Deviation 0.7019641 |
| Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you feel that any difficulty with your hearing limits or hampers your personal or social life? | 0.1666667 score on a scale | Standard Deviation 0.4815434 |
| Radiotherapy, Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty in the movies or in the theater? | 0.4545455 score on a scale | Standard Deviation 0.8201995 |
| Radiotherapy, Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you feel that any difficulty with your hearing limits or hampers your personal or social life? | 0.6363636 score on a scale | Standard Deviation 0.9244163 |
| Radiotherapy, Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you feel handicapped by a hearing problem? | 0.5454545 score on a scale | Standard Deviation 0.9341987 |
| Radiotherapy, Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to feel frustrated when talking to members of your family? | 0.1818182 score on a scale | Standard Deviation 0.6030227 |
| Radiotherapy, Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when listening to TV or radio? | 0.4545455 score on a scale | Standard Deviation 0.8201995 |
| Radiotherapy, Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to feel embarrassed when you meet new people? | 0.5454545 score on a scale | Standard Deviation 0.9341987 |
| Radiotherapy, Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to have argments with family members? | 0.1818182 score on a scale | Standard Deviation 0.6030227 |
| Radiotherapy, Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to attend religious services less often than you would like? | 0.1818182 score on a scale | Standard Deviation 0.6030227 |
| Radiotherapy, Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when in a restaurant with relatives or friends? | 0.7272727 score on a scale | Standard Deviation 0.904534 |
| Radiotherapy, Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you have difficulty hearing or understanding co-workers or clients or customers? | 1.0909091 score on a scale | Standard Deviation 1.0444659 |
| Radiotherapy, Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when visiting friends or relatives or neighbors? | 0.6363636 score on a scale | Standard Deviation 0.9244163 |
| 1 Month - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when listening to TV or radio? | 0.8571429 score on a scale | Standard Deviation 0.9636241 |
| 1 Month - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to feel frustrated when talking to members of your family? | 0.5238095 score on a scale | Standard Deviation 0.8728716 |
| 1 Month - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you feel that any difficulty with your hearing limits or hampers your personal or social life? | 0.3809524 score on a scale | Standard Deviation 0.7400129 |
| 1 Month - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to feel embarrassed when you meet new people? | 0.2380952 score on a scale | Standard Deviation 0.6248809 |
| 1 Month - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you have difficulty hearing or understanding co-workers or clients or customers? | 0.6666667 score on a scale | Standard Deviation 0.9128709 |
| 1 Month - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you feel handicapped by a hearing problem? | 0.1428571 score on a scale | Standard Deviation 0.4780914 |
| 1 Month - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty in the movies or in the theater? | 0.5238095 score on a scale | Standard Deviation 0.8728716 |
| 1 Month - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when in a restaurant with relatives or friends? | 0.6190476 score on a scale | Standard Deviation 0.8646497 |
| 1 Month - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to attend religious services less often than you would like? | 0.0000000 score on a scale | Standard Deviation 0 |
| 1 Month - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to have argments with family members? | 0.1000000 score on a scale | Standard Deviation 0.4472136 |
| 1 Month - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when visiting friends or relatives or neighbors? | 0.1904762 score on a scale | Standard Deviation 0.5117663 |
| 1 Month - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to have argments with family members? | 0.1818182 score on a scale | Standard Deviation 0.6030227 |
| 1 Month - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when visiting friends or relatives or neighbors? | 0.4545455 score on a scale | Standard Deviation 0.8201995 |
| 1 Month - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to attend religious services less often than you would like? | 0.0000000 score on a scale | Standard Deviation 0 |
| 1 Month - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you feel that any difficulty with your hearing limits or hampers your personal or social life? | 0.7272727 score on a scale | Standard Deviation 1.00905 |
| 1 Month - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to feel embarrassed when you meet new people? | 0.1818182 score on a scale | Standard Deviation 0.6030227 |
| 1 Month - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty in the movies or in the theater? | 0.2727273 score on a scale | Standard Deviation 0.6466698 |
| 1 Month - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you feel handicapped by a hearing problem? | 0.3636364 score on a scale | Standard Deviation 0.8090398 |
| 1 Month - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when in a restaurant with relatives or friends? | 0.8181818 score on a scale | Standard Deviation 0.9816498 |
| 1 Month - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you have difficulty hearing or understanding co-workers or clients or customers? | 1.0909091 score on a scale | Standard Deviation 1.0444659 |
| 1 Month - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when listening to TV or radio? | 0.4545455 score on a scale | Standard Deviation 0.8201995 |
| 1 Month - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to feel frustrated when talking to members of your family? | 0.3636364 score on a scale | Standard Deviation 0.8090398 |
| 6 Months - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to feel embarrassed when you meet new people? | 0.1333333 score on a scale | Standard Deviation 0.3518658 |
| 6 Months - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty in the movies or in the theater? | 0.1333333 score on a scale | Standard Deviation 0.5163978 |
| 6 Months - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to feel frustrated when talking to members of your family? | 0.1333333 score on a scale | Standard Deviation 0.3518658 |
| 6 Months - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when in a restaurant with relatives or friends? | 0.2666667 score on a scale | Standard Deviation 0.5936168 |
| 6 Months - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to attend religious services less often than you would like? | 0.0000000 score on a scale | Standard Deviation 0 |
| 6 Months - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you have difficulty hearing or understanding co-workers or clients or customers? | 0.1333333 score on a scale | Standard Deviation 0.3518658 |
| 6 Months - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when visiting friends or relatives or neighbors? | 0.1333333 score on a scale | Standard Deviation 0.3518658 |
| 6 Months - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to have argments with family members? | 0.2666667 score on a scale | Standard Deviation 0.7037316 |
| 6 Months - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when listening to TV or radio? | 0.4000000 score on a scale | Standard Deviation 0.7367884 |
| 6 Months - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you feel handicapped by a hearing problem? | 0.0666667 score on a scale | Standard Deviation 0.2581989 |
| 6 Months - Radiotherapy | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you feel that any difficulty with your hearing limits or hampers your personal or social life? | 0.2000000 score on a scale | Standard Deviation 0.5606119 |
| 6 Months - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when visiting friends or relatives or neighbors? | 0.7142857 score on a scale | Standard Deviation 0.9511897 |
| 6 Months - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you feel handicapped by a hearing problem? | 0.7142857 score on a scale | Standard Deviation 0.9511897 |
| 6 Months - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to feel frustrated when talking to members of your family? | 0.7142857 score on a scale | Standard Deviation 0.9511897 |
| 6 Months - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when in a restaurant with relatives or friends? | 1.5714286 score on a scale | Standard Deviation 0.7867958 |
| 6 Months - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty when listening to TV or radio? | 0.7142857 score on a scale | Standard Deviation 0.9511897 |
| 6 Months - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you feel that any difficulty with your hearing limits or hampers your personal or social life? | 0.7142857 score on a scale | Standard Deviation 0.9511897 |
| 6 Months - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to attend religious services less often than you would like? | 0.0000000 score on a scale | Standard Deviation 0 |
| 6 Months - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you difficulty in the movies or in the theater? | 0.4285714 score on a scale | Standard Deviation 0.7867958 |
| 6 Months - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to feel embarrassed when you meet new people? | 1.0000000 score on a scale | Standard Deviation 1 |
| 6 Months - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Do you have difficulty hearing or understanding co-workers or clients or customers? | 1.7142857 score on a scale | Standard Deviation 0.48795 |
| 6 Months - Radiotherapy + Cisplatin | Change in Hearing as Measured by Hearing Handicap Inventory - Adult | Does a hearing problem cause you to have argments with family members? | 0.1428571 score on a scale | Standard Deviation 0.3779645 |
Secondary
Change in Quality of Life as Measured by EORTC QLQ-C30
* 30 questions designed to assess the quality of life of cancer patients * The first 28 questions have answers that range from 1=not at all to 4 = very much. The higher score indicates a worse quality of life * The last 2 questions have answers that range from 1 = very poor to 7 = excellent. The higher score indicates a better quality of life
Time frame: Baseline, 1 month, 6 months, 12 months, and 24 months
Population: Some participants were not analyzed as the participants did not complete the questionnaires.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment caused you financial difficulties? | 1.5416667 score on a scale | Standard Deviation 1.0206207 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you worry? | 1.9166667 score on a scale | Standard Deviation 0.7755316 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have trouble doing strenuous activities, like carrying a heavy shopping bag or a suitcase? | 2.0000000 score on a scale | Standard Deviation 0.9534626 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in pursuing your hobbies or other leisure time activities? | 2.0000000 score on a scale | Standard Deviation 1.0215078 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in doing either your work or other daily activities? | 2.0833333 score on a scale | Standard Deviation 1.0179548 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall health during the past week? | 5.2083333 score on a scale | Standard Deviation 1.2846643 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need help with eating, dressing, washing yourself or using the toilet? | 1.0833333 score on a scale | Standard Deviation 0.2823299 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did pain interfere with your daily activities? | 1.6666667 score on a scale | Standard Deviation 0.8164966 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you vomited? | 1.0833333 score on a scale | Standard Deviation 0.4082483 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you tired? | 2.0000000 score on a scale | Standard Deviation 0.8846517 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt nauseated? | 1.1666667 score on a scale | Standard Deviation 0.6370221 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel tense? | 1.3750000 score on a scale | Standard Deviation 0.646899 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty in concentrating on things, like reading a newspaper or watching television | 1.4583333 score on a scale | Standard Deviation 0.7790276 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had diarrhea? | 1.0416667 score on a scale | Standard Deviation 0.2041241 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty remembering things? | 1.4166667 score on a scale | Standard Deviation 0.7172815 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you lacked appetite? | 1.6956522 score on a scale | Standard Deviation 0.8756703 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel irritable? | 1.4166667 score on a scale | Standard Deviation 0.8297022 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel depressed? | 1.5416667 score on a scale | Standard Deviation 0.8836272 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had trouble sleeping? | 1.8333333 score on a scale | Standard Deviation 0.8681147 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your family life? | 1.7916667 score on a scale | Standard Deviation 0.8836272 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you need to rest? | 1.9166667 score on a scale | Standard Deviation 0.8805466 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your social activities? | 2.0416667 score on a scale | Standard Deviation 0.9990938 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had pain? | 2.0000000 score on a scale | Standard Deviation 0.7801895 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt weak? | 1.9166667 score on a scale | Standard Deviation 0.9743076 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you short of breath? | 1.2916667 score on a scale | Standard Deviation 0.6240935 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a short walk outside of the house? | 1.0833333 score on a scale | Standard Deviation 0.2823299 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need to stay in bed or a chair during the day? | 1.4583333 score on a scale | Standard Deviation 0.8329709 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall quality of life during the past week? | 5.0416667 score on a scale | Standard Deviation 1.3666578 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a long walk? | 1.7500000 score on a scale | Standard Deviation 0.9440892 |
| Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you been constipated? | 1.5000000 score on a scale | Standard Deviation 0.7801895 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you vomited? | 1.0000000 score on a scale | Standard Deviation 0 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did pain interfere with your daily activities? | 1.7272727 score on a scale | Standard Deviation 0.6466698 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall quality of life during the past week? | 5.1818182 score on a scale | Standard Deviation 0.7507572 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty in concentrating on things, like reading a newspaper or watching television | 1.2727273 score on a scale | Standard Deviation 0.6466698 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel irritable? | 1.5454545 score on a scale | Standard Deviation 0.522233 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need to stay in bed or a chair during the day? | 1.0000000 score on a scale | Standard Deviation 0 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel tense? | 1.5454545 score on a scale | Standard Deviation 0.6875517 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall health during the past week? | 5.2727273 score on a scale | Standard Deviation 0.7862454 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need help with eating, dressing, washing yourself or using the toilet? | 1.0909091 score on a scale | Standard Deviation 0.3015113 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in doing either your work or other daily activities? | 1.6363636 score on a scale | Standard Deviation 1.0269106 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in pursuing your hobbies or other leisure time activities? | 1.6363636 score on a scale | Standard Deviation 1.0269106 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have trouble doing strenuous activities, like carrying a heavy shopping bag or a suitcase? | 2.0000000 score on a scale | Standard Deviation 0.6324555 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment caused you financial difficulties? | 2.3636364 score on a scale | Standard Deviation 1.2060454 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a long walk? | 1.0909091 score on a scale | Standard Deviation 0.6015113 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a short walk outside of the house? | 1.0000000 score on a scale | Standard Deviation 0 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you short of breath? | 1.0000000 score on a scale | Standard Deviation 0 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your social activities? | 1.9090909 score on a scale | Standard Deviation 1.0444659 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had pain? | 1.7272727 score on a scale | Standard Deviation 0.7862454 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you lacked appetite? | 1.6363636 score on a scale | Standard Deviation 0.9244163 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you need to rest? | 1.5454545 score on a scale | Standard Deviation 0.522233 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had trouble sleeping? | 2.2727273 score on a scale | Standard Deviation 1.1908744 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt weak? | 1.8181818 score on a scale | Standard Deviation 0.7507572 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt nauseated? | 1.3636364 score on a scale | Standard Deviation 0.504525 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty remembering things? | 1.2727273 score on a scale | Standard Deviation 0.4670994 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your family life? | 1.5454545 score on a scale | Standard Deviation 0.8201995 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you been constipated? | 1.8181818 score on a scale | Standard Deviation 1.0787198 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel depressed? | 1.4545455 score on a scale | Standard Deviation 0.6875517 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had diarrhea? | 1.1818182 score on a scale | Standard Deviation 0.4045199 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you tired? | 2.0000000 score on a scale | Standard Deviation 0.7745967 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you worry? | 2.0000000 score on a scale | Standard Deviation 0.6324555 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty remembering things? | 1.5454545 score on a scale | Standard Deviation 0.8004328 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had trouble sleeping? | 1.5454545 score on a scale | Standard Deviation 0.6709817 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt nauseated? | 1.1818182 score on a scale | Standard Deviation 0.5010811 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel tense? | 1.4090909 score on a scale | Standard Deviation 0.5903262 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a long walk? | 1.3636364 score on a scale | Standard Deviation 0.5810872 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt weak? | 1.6818182 score on a scale | Standard Deviation 0.8387271 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you lacked appetite? | 1.6363636 score on a scale | Standard Deviation 0.7267314 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in pursuing your hobbies or other leisure time activities? | 1.4545455 score on a scale | Standard Deviation 0.7385489 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need help with eating, dressing, washing yourself or using the toilet? | 1.0909091 score on a scale | Standard Deviation 0.4264014 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall health during the past week? | 5.4090909 score on a scale | Standard Deviation 1.1815684 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had diarrhea? | 1.1363636 score on a scale | Standard Deviation 0.3512501 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did pain interfere with your daily activities? | 1.2380952 score on a scale | Standard Deviation 0.6248809 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a short walk outside of the house? | 1.0454545 score on a scale | Standard Deviation 0.2132007 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have trouble doing strenuous activities, like carrying a heavy shopping bag or a suitcase? | 1.7727273 score on a scale | Standard Deviation 0.9223065 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you worry? | 1.4545455 score on a scale | Standard Deviation 0.5958006 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment caused you financial difficulties? | 1.5909091 score on a scale | Standard Deviation 0.9591212 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you short of breath? | 1.1363636 score on a scale | Standard Deviation 0.3512501 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you been constipated? | 1.6363636 score on a scale | Standard Deviation 0.789542 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel depressed? | 1.3181818 score on a scale | Standard Deviation 0.5679004 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your social activities? | 1.5909091 score on a scale | Standard Deviation 0.7963662 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you tired? | 1.181818 score on a scale | Standard Deviation 0.7950061 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had pain? | 1.5000000 score on a scale | Standard Deviation 0.5976143 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel irritable? | 1.4090909 score on a scale | Standard Deviation 0.6661253 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need to stay in bed or a chair during the day? | 1.2272727 score on a scale | Standard Deviation 0.5284135 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in doing either your work or other daily activities? | 1.4090909 score on a scale | Standard Deviation 0.7341397 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you need to rest? | 1.5909091 score on a scale | Standard Deviation 0.7341397 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you vomited? | 1.0454545 score on a scale | Standard Deviation 0.2132007 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall quality of life during the past week? | 5.6363636 score on a scale | Standard Deviation 1.216766 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your family life? | 1.3181818 score on a scale | Standard Deviation 0.7162311 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty in concentrating on things, like reading a newspaper or watching television | 1.2857143 score on a scale | Standard Deviation 0.5606119 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have trouble doing strenuous activities, like carrying a heavy shopping bag or a suitcase? | 1.4545455 score on a scale | Standard Deviation 0.6875517 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in pursuing your hobbies or other leisure time activities? | 1.4545455 score on a scale | Standard Deviation 0.6875517 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had trouble sleeping? | 1.6363636 score on a scale | Standard Deviation 0.6741999 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment caused you financial difficulties? | 1.9090909 score on a scale | Standard Deviation 1.0444659 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your social activities? | 1.7272727 score on a scale | Standard Deviation 0.904534 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel irritable? | 1.2727273 score on a scale | Standard Deviation 0.6466698 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall quality of life during the past week? | 5.6363636 score on a scale | Standard Deviation 0.8090398 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you been constipated? | 1.0909091 score on a scale | Standard Deviation 0.3015113 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you vomited? | 1.0000000 score on a scale | Standard Deviation 0 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you lacked appetite? | 1.3636364 score on a scale | Standard Deviation 0.504525 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel depressed? | 1.1818182 score on a scale | Standard Deviation 0.4045199 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt weak? | 1.4545455 score on a scale | Standard Deviation 0.522233 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a long walk? | 1.2727273 score on a scale | Standard Deviation 0.4670994 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you short of breath? | 1.3636364 score on a scale | Standard Deviation 0.504525 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt nauseated? | 1.1818182 score on a scale | Standard Deviation 0.4045199 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had pain? | 1.7272727 score on a scale | Standard Deviation 0.904534 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty remembering things? | 1.6363636 score on a scale | Standard Deviation 0.504525 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need help with eating, dressing, washing yourself or using the toilet? | 1.0000000 score on a scale | Standard Deviation 0 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in doing either your work or other daily activities? | 1.2727273 score on a scale | Standard Deviation 0.6466698 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had diarrhea? | 1.0000000 score on a scale | Standard Deviation 0 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel tense? | 1.2727273 score on a scale | Standard Deviation 0.4670994 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need to stay in bed or a chair during the day? | 1.0909091 score on a scale | Standard Deviation 0.3015113 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you worry? | 1.2727273 score on a scale | Standard Deviation 0.4670994 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you need to rest? | 1.6363636 score on a scale | Standard Deviation 0.6741999 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty in concentrating on things, like reading a newspaper or watching television | 1.2727273 score on a scale | Standard Deviation 0.6466698 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a short walk outside of the house? | 1.0000000 score on a scale | Standard Deviation 0 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall health during the past week? | 5.5454545 score on a scale | Standard Deviation 0.8201995 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did pain interfere with your daily activities? | 1.3000000 score on a scale | Standard Deviation 0.4830459 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you tired? | 1.7272727 score on a scale | Standard Deviation 0.6466698 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your family life? | 1.3636364 score on a scale | Standard Deviation 0.504525 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall quality of life during the past week? | 6.1428571 score on a scale | Standard Deviation 1.3506205 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have trouble doing strenuous activities, like carrying a heavy shopping bag or a suitcase? | 1.3571429 score on a scale | Standard Deviation 0.6333237 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had pain? | 1.7142857 score on a scale | Standard Deviation 0.8254203 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a long walk? | 1.2142857 score on a scale | Standard Deviation 0.4258153 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a short walk outside of the house? | 1.0714286 score on a scale | Standard Deviation 0.2672612 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you need to rest? | 1.5000000 score on a scale | Standard Deviation 0.7595545 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your social activities? | 1.1428571 score on a scale | Standard Deviation 0.3631365 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you worry? | 1.3571429 score on a scale | Standard Deviation 0.4972452 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you short of breath? | 1.1428571 score on a scale | Standard Deviation 0.3631365 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall health during the past week? | 5.9285714 score on a scale | Standard Deviation 1.2688145 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you tired? | 1.6428571 score on a scale | Standard Deviation 0.8418974 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your family life? | 1.2142857 score on a scale | Standard Deviation 0.4258153 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty in concentrating on things, like reading a newspaper or watching television | 1.3571429 score on a scale | Standard Deviation 0.7449463 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had trouble sleeping? | 1.3571429 score on a scale | Standard Deviation 0.6333237 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty remembering things? | 1.7142857 score on a scale | Standard Deviation 0.8254203 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt weak? | 1.5384615 score on a scale | Standard Deviation 0.877058 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in pursuing your hobbies or other leisure time activities? | 1.2857143 score on a scale | Standard Deviation 0.6112498 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you lacked appetite? | 1.3571429 score on a scale | Standard Deviation 0.6333237 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel irritable? | 1.1428571 score on a scale | Standard Deviation 0.5345225 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment caused you financial difficulties? | 1.7142857 score on a scale | Standard Deviation 0.9944903 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt nauseated? | 1.2142857 score on a scale | Standard Deviation 0.4258153 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel tense? | 1.2857143 score on a scale | Standard Deviation 0.4688072 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel depressed? | 1.2142857 score on a scale | Standard Deviation 0.4258153 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you vomited? | 1.0714286 score on a scale | Standard Deviation 0.2672612 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you been constipated? | 1.2142857 score on a scale | Standard Deviation 0.4258153 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did pain interfere with your daily activities? | 1.2857143 score on a scale | Standard Deviation 0.6112498 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had diarrhea? | 1.1428571 score on a scale | Standard Deviation 0.3631365 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need help with eating, dressing, washing yourself or using the toilet? | 1.0714286 score on a scale | Standard Deviation 0.2672612 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in doing either your work or other daily activities? | 1.4285714 score on a scale | Standard Deviation 0.6462062 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need to stay in bed or a chair during the day? | 1.1428571 score on a scale | Standard Deviation 0.3631365 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment caused you financial difficulties? | 2.1428571 score on a scale | Standard Deviation 1.069045 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt nauseated? | 1.1428571 score on a scale | Standard Deviation 0.3779645 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you need to rest? | 1.7142857 score on a scale | Standard Deviation 0.7559289 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have trouble doing strenuous activities, like carrying a heavy shopping bag or a suitcase? | 1.7142857 score on a scale | Standard Deviation 0.7559289 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a short walk outside of the house? | 1.1428571 score on a scale | Standard Deviation 0.3779645 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in doing either your work or other daily activities? | 1.1428571 score on a scale | Standard Deviation 0.3779645 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your social activities? | 1.7142857 score on a scale | Standard Deviation 0.7559289 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you tired? | 1.8571429 score on a scale | Standard Deviation 0.6900656 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your family life? | 1.4285714 score on a scale | Standard Deviation 0.7867958 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you vomited? | 1.0000000 score on a scale | Standard Deviation 0 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in pursuing your hobbies or other leisure time activities? | 1.4285714 score on a scale | Standard Deviation 0.7867958 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel tense? | 1.5714286 score on a scale | Standard Deviation 0.7867958 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a long walk? | 1.1428571 score on a scale | Standard Deviation 0.3779645 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you lacked appetite? | 1.2857143 score on a scale | Standard Deviation 0.48795 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need help with eating, dressing, washing yourself or using the toilet? | 1.1428571 score on a scale | Standard Deviation 0.3779645 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had pain? | 1.8571429 score on a scale | Standard Deviation 0.8997354 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had diarrhea? | 1.1428571 score on a scale | Standard Deviation 0.3779645 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did pain interfere with your daily activities? | 1.4285714 score on a scale | Standard Deviation 0.7867958 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty in concentrating on things, like reading a newspaper or watching television | 1.5714286 score on a scale | Standard Deviation 0.7867958 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt weak? | 1.4285714 score on a scale | Standard Deviation 0.7867958 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you worry? | 2.0000000 score on a scale | Standard Deviation 0.8164966 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you short of breath? | 1.4285714 score on a scale | Standard Deviation 0.7867958 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall health during the past week? | 5.2857143 score on a scale | Standard Deviation 1.1126973 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty remembering things? | 1.8571429 score on a scale | Standard Deviation 0.8997354 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall quality of life during the past week? | 5.4285714 score on a scale | Standard Deviation 0.7867958 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel depressed? | 1.5714286 score on a scale | Standard Deviation 0.9759001 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you been constipated? | 1.1428571 score on a scale | Standard Deviation 0.3779645 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel irritable? | 1.7142857 score on a scale | Standard Deviation 0.9511897 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need to stay in bed or a chair during the day? | 1.2857143 score on a scale | Standard Deviation 0.48795 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had trouble sleeping? | 2.4285714 score on a scale | Standard Deviation 0.9759001 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you lacked appetite? | 1.2000000 score on a scale | Standard Deviation 0.5606119 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt nauseated? | 1.1333333 score on a scale | Standard Deviation 0.5163978 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel depressed? | 1.3333333 score on a scale | Standard Deviation 0.8164966 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you worry? | 1.4000000 score on a scale | Standard Deviation 0.8280787 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you need to rest? | 1.6000000 score on a scale | Standard Deviation 0.7367884 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall health during the past week? | 6.0666667 score on a scale | Standard Deviation 1.0327956 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel tense? | 1.4000000 score on a scale | Standard Deviation 0.8280787 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty remembering things? | 1.6000000 score on a scale | Standard Deviation 0.6324555 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel irritable? | 1.3333333 score on a scale | Standard Deviation 0.8164966 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did pain interfere with your daily activities? | 1.3333333 score on a scale | Standard Deviation 0.6172134 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you vomited? | 1.0000000 score on a scale | Standard Deviation 0 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment caused you financial difficulties? | 1.4666667 score on a scale | Standard Deviation 1.0600988 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you short of breath? | 1.2666667 score on a scale | Standard Deviation 0.5936168 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have trouble doing strenuous activities, like carrying a heavy shopping bag or a suitcase? | 1.2666667 score on a scale | Standard Deviation 0.5936168 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you been constipated? | 1.1333333 score on a scale | Standard Deviation 0.3518658 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in pursuing your hobbies or other leisure time activities? | 1.1333333 score on a scale | Standard Deviation 0.5163978 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a short walk outside of the house? | 1.0000000 score on a scale | Standard Deviation 0 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your social activities? | 1.3333333 score on a scale | Standard Deviation 0.6172134 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had pain? | 1.6000000 score on a scale | Standard Deviation 0.7367884 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in doing either your work or other daily activities? | 1.2000000 score on a scale | Standard Deviation 0.5606119 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a long walk? | 1.2666667 score on a scale | Standard Deviation 0.4577377 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had diarrhea? | 1.2000000 score on a scale | Standard Deviation 0.4140393 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need help with eating, dressing, washing yourself or using the toilet? | 1.0000000 score on a scale | Standard Deviation 0 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall quality of life during the past week? | 6.1333333 score on a scale | Standard Deviation 1.0600988 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt weak? | 1.3333333 score on a scale | Standard Deviation 0.6172134 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your family life? | 1.2000000 score on a scale | Standard Deviation 0.4140393 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need to stay in bed or a chair during the day? | 1.2666667 score on a scale | Standard Deviation 0.4577377 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you tired? | 1.7333333 score on a scale | Standard Deviation 0.8837151 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had trouble sleeping? | 1.9333333 score on a scale | Standard Deviation 0.9611501 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty in concentrating on things, like reading a newspaper or watching television | 1.4000000 score on a scale | Standard Deviation 0.910259 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a short walk outside of the house? | 1.1428571 score on a scale | Standard Deviation 0.3779645 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall health during the past week? | 5.5714286 score on a scale | Standard Deviation 1.1338934 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need to stay in bed or a chair during the day? | 1.2857143 score on a scale | Standard Deviation 0.48795 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need help with eating, dressing, washing yourself or using the toilet? | 1.2857143 score on a scale | Standard Deviation 0.48795 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in doing either your work or other daily activities? | 1.2857143 score on a scale | Standard Deviation 0.48795 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have trouble doing strenuous activities, like carrying a heavy shopping bag or a suitcase? | 1.5714286 score on a scale | Standard Deviation 0.7867958 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a long walk? | 1.1428571 score on a scale | Standard Deviation 0.3779645 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in pursuing your hobbies or other leisure time activities? | 1.4285714 score on a scale | Standard Deviation 0.7867958 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you short of breath? | 1.4285714 score on a scale | Standard Deviation 0.7867958 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had pain? | 1.8571429 score on a scale | Standard Deviation 0.8997354 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you need to rest? | 1.8571429 score on a scale | Standard Deviation 0.6900656 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had trouble sleeping? | 2.0000000 score on a scale | Standard Deviation 0.8164966 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt weak? | 1.5714286 score on a scale | Standard Deviation 0.7867958 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you lacked appetite? | 1.2857143 score on a scale | Standard Deviation 0.7559289 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt nauseated? | 1.0000000 score on a scale | Standard Deviation 0 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel tense? | 1.4285714 score on a scale | Standard Deviation 0.7867958 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you vomited? | 1.0000000 score on a scale | Standard Deviation 0 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you been constipated? | 1.5714286 score on a scale | Standard Deviation 0.9759001 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had diarrhea? | 1.1428571 score on a scale | Standard Deviation 0.3779645 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you tired? | 2.1428571 score on a scale | Standard Deviation 0.6900656 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you worry? | 2.0000000 score on a scale | Standard Deviation 0.8164966 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did pain interfere with your daily activities? | 1.5714286 score on a scale | Standard Deviation 0.7867958 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty in concentrating on things, like reading a newspaper or watching television | 1.5714286 score on a scale | Standard Deviation 0.7867958 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel irritable? | 1.8571429 score on a scale | Standard Deviation 0.6900656 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel depressed? | 1.7142857 score on a scale | Standard Deviation 0.7559289 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty remembering things? | 2.1428571 score on a scale | Standard Deviation 0.8997354 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your family life? | 1.5714286 score on a scale | Standard Deviation 0.7867958 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your social activities? | 1.5714286 score on a scale | Standard Deviation 0.7867958 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment caused you financial difficulties? | 1.8571429 score on a scale | Standard Deviation 0.8997354 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall quality of life during the past week? | 5.7142857 score on a scale | Standard Deviation 1.1126973 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you short of breath? | 1.1875000 score on a scale | Standard Deviation 0.5439056 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty in concentrating on things, like reading a newspaper or watching television | 1.3125000 score on a scale | Standard Deviation 0.6020797 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in pursuing your hobbies or other leisure time activities? | 1.2500000 score on a scale | Standard Deviation 0.5773503 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt weak? | 1.5625000 score on a scale | Standard Deviation 0.7274384 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a long walk? | 1.2500000 score on a scale | Standard Deviation 0.4472136 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you tired? | 1.4375000 score on a scale | Standard Deviation 0.6291529 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your social activities? | 1.1250000 score on a scale | Standard Deviation 0.341565 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had trouble sleeping? | 1.3750000 score on a scale | Standard Deviation 0.6191392 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt nauseated? | 1.1875000 score on a scale | Standard Deviation 0.4031129 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have trouble doing strenuous activities, like carrying a heavy shopping bag or a suitcase? | 1.4375000 score on a scale | Standard Deviation 0.6291529 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty remembering things? | 1.4375000 score on a scale | Standard Deviation 0.5123475 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel depressed? | 1.3125000 score on a scale | Standard Deviation 0.6020797 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall quality of life during the past week? | 6.0000000 score on a scale | Standard Deviation 1.0954451 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment caused you financial difficulties? | 1.4375000 score on a scale | Standard Deviation 0.813941 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need help with eating, dressing, washing yourself or using the toilet? | 1.0000000 score on a scale | Standard Deviation 0 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you vomited? | 1.0000000 score on a scale | Standard Deviation 0 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need to stay in bed or a chair during the day? | 1.1875000 score on a scale | Standard Deviation 0.5439056 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you need to rest? | 1.6875000 score on a scale | Standard Deviation 0.7041543 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall health during the past week? | 5.7500000 score on a scale | Standard Deviation 1.183216 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you been constipated? | 1.4000000 score on a scale | Standard Deviation 0.8280787 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a short walk outside of the house? | 1.0000000 score on a scale | Standard Deviation 0 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in doing either your work or other daily activities? | 1.3750000 score on a scale | Standard Deviation 0.8062258 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel tense? | 1.1875000 score on a scale | Standard Deviation 0.4031129 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you worry? | 1.4375000 score on a scale | Standard Deviation 0.7274384 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had pain? | 1.6875000 score on a scale | Standard Deviation 0.7932003 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your family life? | 1.0625000 score on a scale | Standard Deviation 0.25 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did pain interfere with your daily activities? | 1.1333333 score on a scale | Standard Deviation 0.3518658 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you lacked appetite? | 1.5000000 score on a scale | Standard Deviation 0.8944272 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had diarrhea? | 1.0666667 score on a scale | Standard Deviation 0.2581989 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel irritable? | 1.3125000 score on a scale | Standard Deviation 0.6020797 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you tired? | 1.7500000 score on a scale | Standard Deviation 0.46291 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel irritable? | 1.6250000 score on a scale | Standard Deviation 0.9161254 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you been constipated? | 1.7500000 score on a scale | Standard Deviation 1.1649647 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you vomited? | 1.0000000 score on a scale | Standard Deviation 0 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel tense? | 1.7500000 score on a scale | Standard Deviation 1.0350983 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt nauseated? | 1.0000000 score on a scale | Standard Deviation 0 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty in concentrating on things, like reading a newspaper or watching television | 1.2500000 score on a scale | Standard Deviation 0.46291 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you lacked appetite? | 1.1250000 score on a scale | Standard Deviation 0.3535534 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you feel depressed? | 1.5000000 score on a scale | Standard Deviation 0.7559289 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you felt weak? | 1.3750000 score on a scale | Standard Deviation 0.5175492 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had trouble sleeping? | 2.1250000 score on a scale | Standard Deviation 0.6408699 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had difficulty remembering things? | 1.8750000 score on a scale | Standard Deviation 0.6408699 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you need to rest? | 1.6250000 score on a scale | Standard Deviation 0.7440238 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had pain? | 2.0000000 score on a scale | Standard Deviation 0.7559289 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your family life? | 1.1250000 score on a scale | Standard Deviation 0.3535534 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you short of breath? | 1.3750000 score on a scale | Standard Deviation 0.5175492 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in pursuing your hobbies or other leisure time activities? | 1.3750000 score on a scale | Standard Deviation 0.7440238 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a long walk? | 1.2500000 score on a scale | Standard Deviation 0.46291 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall quality of life during the past week? | 6.0000000 score on a scale | Standard Deviation 0.5345225 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment interfered with your social activities? | 1.3750000 score on a scale | Standard Deviation 0.5175492 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have trouble doing strenuous activities, like carrying a heavy shopping bag or a suitcase? | 1.6250000 score on a scale | Standard Deviation 0.5175492 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Were you limited in doing either your work or other daily activities? | 1.0000000 score on a scale | Standard Deviation 0 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need help with eating, dressing, washing yourself or using the toilet? | 1.0000000 score on a scale | Standard Deviation 0 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you need to stay in bed or a chair during the day? | 1.0000000 score on a scale | Standard Deviation 0 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Do you have any trouble taking a short walk outside of the house? | 1.1250000 score on a scale | Standard Deviation 0.3535534 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | How would you rate your overall health during the past week? | 5.7500000 score on a scale | Standard Deviation 0.7071068 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Has your physical condition or medical treatment caused you financial difficulties? | 1.8750000 score on a scale | Standard Deviation 0.9910312 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did you worry? | 2.0000000 score on a scale | Standard Deviation 0.7559289 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Did pain interfere with your daily activities? | 1.0000000 score on a scale | Standard Deviation 0 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by EORTC QLQ-C30 | Have you had diarrhea? | 1.1250000 score on a scale | Standard Deviation 0.3535534 |
Secondary
Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII)
-The NDII consists of 10 questions; each with a 5 level ordinally scaled response option ranging from not at all to a lot. The response for each item is then scored from 1 to 5, with 5 denoting higher quality of life (Not at all) and 1 being the least (A lot).
Time frame: Baseline, 12 months, and 24 months
Population: Some participants were not analyzed as the participants did not complete the questionnaires.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Neck or shoulder pain or discomfort | 1.6086957 score on a scale | Standard Deviation 1.117592 |
| Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to reach for objects because of your shoulder or neck | 1.2173913 score on a scale | Standard Deviation 1.3802675 |
| Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Overall activity level because of your shoulder or neck | 1.0000000 score on a scale | Standard Deviation 1.2431631 |
| Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited in ability to do work including work at home because of neck or shoulder discomfort or pain? | 1.1304348 score on a scale | Standard Deviation 1.3916749 |
| Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Neck or shoulder stiffness | 1.4545455 score on a scale | Standard Deviation 1.1433981 |
| Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited in ability to do leisure or recreational activities because of your neck or shoulder? | 1.0869565 score on a scale | Standard Deviation 1.3788349 |
| Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Difficulty with self-care activities because of neck or shoulder | 0.8695652 score on a scale | Standard Deviation 0.9197009 |
| Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to life light objects because of your shoulder or neck | 0.6521739 score on a scale | Standard Deviation 0.8846517 |
| Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Has the treatment of your neck affected your participation in social activities? | 0.7391304 score on a scale | Standard Deviation 1.1368774 |
| Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to lift heavy objects because of your shoulder or neck | 1.6086957 score on a scale | Standard Deviation 1.3395769 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Neck or shoulder pain or discomfort | 2.0909091 score on a scale | Standard Deviation 1.2210279 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited in ability to do work including work at home because of neck or shoulder discomfort or pain? | 1.7272727 score on a scale | Standard Deviation 1.6180797 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited in ability to do leisure or recreational activities because of your neck or shoulder? | 1.7272727 score on a scale | Standard Deviation 1.4893562 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to lift heavy objects because of your shoulder or neck | 2.2727273 score on a scale | Standard Deviation 1.4206273 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Difficulty with self-care activities because of neck or shoulder | 1.2727273 score on a scale | Standard Deviation 1.1037127 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Has the treatment of your neck affected your participation in social activities? | 0.9090909 score on a scale | Standard Deviation 1.2210279 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Overall activity level because of your shoulder or neck | 1.9090909 score on a scale | Standard Deviation 1.5782614 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to reach for objects because of your shoulder or neck | 2.0909091 score on a scale | Standard Deviation 1.5135749 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to life light objects because of your shoulder or neck | 1.6363636 score on a scale | Standard Deviation 1.4333686 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Neck or shoulder stiffness | 2.0000000 score on a scale | Standard Deviation 1.2649111 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Neck or shoulder pain or discomfort | 1.4666667 score on a scale | Standard Deviation 0.9904304 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Neck or shoulder stiffness | 1.0000000 score on a scale | Standard Deviation 0.8451543 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited in ability to do leisure or recreational activities because of your neck or shoulder? | 0.2000000 score on a scale | Standard Deviation 0.5606119 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to reach for objects because of your shoulder or neck | 0.5333333 score on a scale | Standard Deviation 0.8338094 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to lift heavy objects because of your shoulder or neck | 0.5333333 score on a scale | Standard Deviation 0.9904304 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Overall activity level because of your shoulder or neck | 0.5333333 score on a scale | Standard Deviation 0.8338094 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to life light objects because of your shoulder or neck | 0.4000000 score on a scale | Standard Deviation 0.7367884 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Difficulty with self-care activities because of neck or shoulder | 0.3333333 score on a scale | Standard Deviation 0.8164966 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited in ability to do work including work at home because of neck or shoulder discomfort or pain? | 0.2666667 score on a scale | Standard Deviation 0.5936168 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Has the treatment of your neck affected your participation in social activities? | 0.0666667 score on a scale | Standard Deviation 0.2581989 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to lift heavy objects because of your shoulder or neck | 1.5714286 score on a scale | Standard Deviation 1.7182494 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Neck or shoulder pain or discomfort | 2.4285714 score on a scale | Standard Deviation 1.5118579 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Neck or shoulder stiffness | 2.4285714 score on a scale | Standard Deviation 1.5118579 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Difficulty with self-care activities because of neck or shoulder | 1.0000000 score on a scale | Standard Deviation 1 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to life light objects because of your shoulder or neck | 0.8571429 score on a scale | Standard Deviation 1.069045 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to reach for objects because of your shoulder or neck | 1.7142857 score on a scale | Standard Deviation 1.6035675 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Overall activity level because of your shoulder or neck | 1.5714286 score on a scale | Standard Deviation 1.5118579 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Has the treatment of your neck affected your participation in social activities? | 0.8571429 score on a scale | Standard Deviation 0.8997354 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited in ability to do leisure or recreational activities because of your neck or shoulder? | 1.4285714 score on a scale | Standard Deviation 1.272418 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited in ability to do work including work at home because of neck or shoulder discomfort or pain? | 1.2857143 score on a scale | Standard Deviation 1.1126973 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Overall activity level because of your shoulder or neck | 0.3750000 score on a scale | Standard Deviation 0.6191392 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Neck or shoulder stiffness | 1.1875000 score on a scale | Standard Deviation 1.0468206 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Difficulty with self-care activities because of neck or shoulder | 0.2500000 score on a scale | Standard Deviation 0.5773503 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited in ability to do work including work at home because of neck or shoulder discomfort or pain? | 0.1250000 score on a scale | Standard Deviation 0.341565 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited in ability to do leisure or recreational activities because of your neck or shoulder? | 0.2500000 score on a scale | Standard Deviation 0.4472136 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Neck or shoulder pain or discomfort | 1.3125000 score on a scale | Standard Deviation 0.8732125 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Has the treatment of your neck affected your participation in social activities? | 0.1875000 score on a scale | Standard Deviation 0.4031129 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to reach for objects because of your shoulder or neck | 0.5625000 score on a scale | Standard Deviation 0.9639329 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to life light objects because of your shoulder or neck | 0.2500000 score on a scale | Standard Deviation 0.5773503 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to lift heavy objects because of your shoulder or neck | 0.4666667 score on a scale | Standard Deviation 0.8338094 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Neck or shoulder stiffness | 1.7500000 score on a scale | Standard Deviation 1.3887301 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Overall activity level because of your shoulder or neck | 0.6250000 score on a scale | Standard Deviation 0.7440238 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Difficulty with self-care activities because of neck or shoulder | 0.5000000 score on a scale | Standard Deviation 1.4142136 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited in ability to do work including work at home because of neck or shoulder discomfort or pain? | 0.5000000 score on a scale | Standard Deviation 1.069045 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Has the treatment of your neck affected your participation in social activities? | 0.5000000 score on a scale | Standard Deviation 1.069045 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to life light objects because of your shoulder or neck | 0.5000000 score on a scale | Standard Deviation 0.7559289 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Neck or shoulder pain or discomfort | 1.7500000 score on a scale | Standard Deviation 1.2817399 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to lift heavy objects because of your shoulder or neck | 0.8750000 score on a scale | Standard Deviation 0.9910312 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited in ability to do leisure or recreational activities because of your neck or shoulder? | 0.7500000 score on a scale | Standard Deviation 1.1649647 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Neck Dissection Impairment Index (NDII) | Limited ability to reach for objects because of your shoulder or neck | 0.7500000 score on a scale | Standard Deviation 1.0350983 |
Secondary
Change in Quality of Life as Measured by Scale of Subjective Total Taste Acuity
* 1 question that asks about taste acuity * Answers are 0 = same taste acuity as before treatment; 1 = mild loss of taste acuity, but not inconvenient in daily life; moderate loss of taste acuity, and sometimes inconvenient in daily life; severe loss of taste acuity, and frequently inconvenient in daily life; and 4 = almost complete or complete loss of taste acuity * The higher the score the worse the participant's taste acuity
Time frame: Baseline, 1 month, 6 months, and 12 months
Population: Some participants were not analyzed as the participants did not complete the questionnaires.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Radiotherapy | Change in Quality of Life as Measured by Scale of Subjective Total Taste Acuity | 1.0833333 score on a scale | Standard Deviation 1.1000659 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Scale of Subjective Total Taste Acuity | 0.9090909 score on a scale | Standard Deviation 0.8312094 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Scale of Subjective Total Taste Acuity | 2.1363636 score on a scale | Standard Deviation 1.0821255 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Scale of Subjective Total Taste Acuity | 2.9090909 score on a scale | Standard Deviation 1.0444659 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by Scale of Subjective Total Taste Acuity | 0.9285714 score on a scale | Standard Deviation 0.7300459 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Scale of Subjective Total Taste Acuity | 2.4285714 score on a scale | Standard Deviation 0.9759001 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by Scale of Subjective Total Taste Acuity | 1.0000000 score on a scale | Standard Deviation 0.7559289 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Scale of Subjective Total Taste Acuity | 1.5714286 score on a scale | Standard Deviation 0.7867958 |
Secondary
Change in Quality of Life as Measured by Speech Handicap Index
* 31 questions regarding participant's speech and the effects of speech on his/her life * The answers for the first 30 questions range from 0 = never to 4 = always and the answers for the 31st question ranges from 0 = excellent to bad = 4 * The higher the score the worse the participant's speech is affecting his/her life
Time frame: Baseline and 12 months
Population: Some participants were not analyzed as the participants did not complete the questionnaires.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My speaking difficulties restrict my person and social life | 1.3750000 score on a scale | Standard Deviation 0.646899 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I find other people don't understand my speaking problem | 1.1666667 score on a scale | Standard Deviation 0.3806935 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My articulation is unclear | 1.8333333 score on a scale | Standard Deviation 0.9630868 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | The intelligibility of my speech varies throughout the day | 2.0000000 score on a scale | Standard Deviation 1.0632191 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I feel ask though I have to strain to speak | 1.833333 score on a scale | Standard Deviation 0.9630868 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I speak with friends and neighbors and relatives less often because of my speech | 1.4166667 score on a scale | Standard Deviation 0.7172815 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | People have difficulty understanding me in a noisy room | 1.8750000 score on a scale | Standard Deviation 1.0347232 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | The intelligibility is unpredictable | 1.5833333 score on a scale | Standard Deviation 0.8805466 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | People ask me to repeat myself when speaking face-to-face | 1.5416667 score on a scale | Standard Deviation 0.7790276 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | People seem irritated with my speech | 1.1250000 score on a scale | Standard Deviation 0.337832 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I tend to avoid groups of people because of my speech | 1.2500000 score on a scale | Standard Deviation 0.6079188 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My speech makes me feel handicapped | 1.3333333 score on a scale | Standard Deviation 0.7019641 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My family has difficulty understanding me when I call them throughout the house | 1.5000000 score on a scale | Standard Deviation 0.7801895 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My speech makes me feel incompetent | 1.3750000 score on a scale | Standard Deviation 0.646899 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My speech makes it difficult for people to understand me | 1.9565217 score on a scale | Standard Deviation 1.0215078 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I am less outgoing because of my speech problem | 1.2500000 score on a scale | Standard Deviation 0.5316095 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I run out of air when I speak | 1.5000000 score on a scale | Standard Deviation 0.7223151 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | People ask me why I'm hard to understand | 1.2916667 score on a scale | Standard Deviation 0.6240935 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | How do you rate your own speech at this moment? | 2.1304348 score on a scale | Standard Deviation 0.9678631 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My speech problem upsets me | 1.2083333 score on a scale | Standard Deviation 0.4148511 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I try to change my speech to sound different | 1.2916667 score on a scale | Standard Deviation 0.8064504 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I feel annoyed when people ask me to repeat | 1.3750000 score on a scale | Standard Deviation 0.8242256 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I'm ashamed of my speech problem | 1.0833333 score on a scale | Standard Deviation 0.2823299 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My speech problem causes me to lose income | 1.2916667 score on a scale | Standard Deviation 0.6902531 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My speech is worse in the evening | 1.6250000 score on a scale | Standard Deviation 0.8753881 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I avoid using the phone | 1.6250000 score on a scale | Standard Deviation 1.2091139 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I feel embarrassed when people ask me to repeat | 1.2083333 score on a scale | Standard Deviation 0.5089774 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I use a great deal of effort to speak | 1.8750000 score on a scale | Standard Deviation 0.9469631 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I feel left out of conversations because of my speech | 1.2083333 score on a scale | Standard Deviation 0.4148511 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I'm tense when talking to others because of my speech | 1.4166667 score on a scale | Standard Deviation 0.7172815 |
| Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I have difficulties to continue a conversation because of my speech | 1.5000000 score on a scale | Standard Deviation 0.7801895 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My speech problem upsets me | 1.5454545 score on a scale | Standard Deviation 0.8201995 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I run out of air when I speak | 1.4545455 score on a scale | Standard Deviation 0.6875517 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My speech makes it difficult for people to understand me | 1.7272727 score on a scale | Standard Deviation 0.904534 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | The intelligibility of my speech varies throughout the day | 1.5454545 score on a scale | Standard Deviation 0.8201995 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My speech makes me feel incompetent | 1.2727273 score on a scale | Standard Deviation 0.6466698 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | People ask me why I'm hard to understand | 1.1818182 score on a scale | Standard Deviation 0.4045199 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I feel annoyed when people ask me to repeat | 1.2727273 score on a scale | Standard Deviation 0.6466698 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I avoid using the phone | 1.5454545 score on a scale | Standard Deviation 0.9341987 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I'm tense when talking to others because of my speech | 1.5454545 score on a scale | Standard Deviation 0.8201995 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My articulation is unclear | 1.8181818 score on a scale | Standard Deviation 1.3506205 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | People have difficulty understanding me in a noisy room | 1.8181818 score on a scale | Standard Deviation 0.9816498 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I tend to avoid groups of people because of my speech | 1.727277 score on a scale | Standard Deviation 0.904534 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | People seem irritated with my speech | 1.3636364 score on a scale | Standard Deviation 0.504525 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | People ask me to repeat myself when speaking face-to-face | 1.7272727 score on a scale | Standard Deviation 0.904534 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I speak with friends and neighbors and relatives less often because of my speech | 1.2727273 score on a scale | Standard Deviation 0.6466698 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I feel ask though I have to strain to speak | 1.9090909 score on a scale | Standard Deviation 1.1361818 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I find other people don't understand my speaking problem | 1.2727273 score on a scale | Standard Deviation 0.6466698 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My speaking difficulties restrict my person and social life | 1.2727273 score on a scale | Standard Deviation 0.6466698 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | The intelligibility is unpredictable | 1.3636364 score on a scale | Standard Deviation 0.8090398 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I feel left out of conversations because of my speech | 1.3636364 score on a scale | Standard Deviation 0.6741999 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I use a great deal of effort to speak | 1.6363636 score on a scale | Standard Deviation 0.9244163 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My speech is worse in the evening | 1.6363636 score on a scale | Standard Deviation 0.9244163 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My speech problem causes me to lose income | 1.8181818 score on a scale | Standard Deviation 1.2504545 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I try to change my speech to sound different | 1.0909091 score on a scale | Standard Deviation 0.3015113 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I am less outgoing because of my speech problem | 1.4545455 score on a scale | Standard Deviation 0.6875517 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My family has difficulty understanding me when I call them throughout the house | 1.6363636 score on a scale | Standard Deviation 0.8090398 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My speech makes me feel handicapped | 1.4545455 score on a scale | Standard Deviation 0.6875517 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I have difficulties to continue a conversation because of my speech | 1.5454545 score on a scale | Standard Deviation 0.8201995 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I feel embarrassed when people ask me to repeat | 1.3636364 score on a scale | Standard Deviation 0.9244163 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I'm ashamed of my speech problem | 1.2727273 score on a scale | Standard Deviation 0.904534 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | How do you rate your own speech at this moment? | 1.4545455 score on a scale | Standard Deviation 0.522233 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I use a great deal of effort to speak | 1.2666667 score on a scale | Standard Deviation 0.4577377 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My speech problem upsets me | 1.2666667 score on a scale | Standard Deviation 0.4577377 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I have difficulties to continue a conversation because of my speech | 1.1333333 score on a scale | Standard Deviation 0.3518658 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My speech makes me feel incompetent | 1.1333333 score on a scale | Standard Deviation 0.3518658 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | How do you rate your own speech at this moment? | 1.3846154 score on a scale | Standard Deviation 0.6504436 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I am less outgoing because of my speech problem | 1.0666667 score on a scale | Standard Deviation 0.2581989 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My speaking difficulties restrict my person and social life | 1.2000000 score on a scale | Standard Deviation 0.5606119 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I feel embarrassed when people ask me to repeat | 1.0000000 score on a scale | Standard Deviation 0 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I'm ashamed of my speech problem | 1.0000000 score on a scale | Standard Deviation 0 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My family has difficulty understanding me when I call them throughout the house | 1.1333333 score on a scale | Standard Deviation 0.5163978 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My speech is worse in the evening | 1.3333333 score on a scale | Standard Deviation 0.7237469 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | The intelligibility of my speech varies throughout the day | 1.4000000 score on a scale | Standard Deviation 0.7367884 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I tend to avoid groups of people because of my speech | 1.2666667 score on a scale | Standard Deviation 0.7988086 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I find other people don't understand my speaking problem | 1.0666667 score on a scale | Standard Deviation 0.2581989 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I feel annoyed when people ask me to repeat | 1.3333333 score on a scale | Standard Deviation 0.48795 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I feel left out of conversations because of my speech | 1.3333333 score on a scale | Standard Deviation 0.8164966 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | People seem irritated with my speech | 1.1333333 score on a scale | Standard Deviation 0.3518658 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My speech problem causes me to lose income | 1.0000000 score on a scale | Standard Deviation 0 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | People have difficulty understanding me in a noisy room | 1.6000000 score on a scale | Standard Deviation 0.9856108 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My speech makes me feel handicapped | 1.0666667 score on a scale | Standard Deviation 0.2581989 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | People ask me to repeat myself when speaking face-to-face | 1.3333333 score on a scale | Standard Deviation 0.48795 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I'm tense when talking to others because of my speech | 1.0666667 score on a scale | Standard Deviation 0.2581989 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I avoid using the phone | 1.1333333 score on a scale | Standard Deviation 0.3518658 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My speech makes it difficult for people to understand me | 1.3333333 score on a scale | Standard Deviation 0.6172134 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I speak with friends and neighbors and relatives less often because of my speech | 1.2666667 score on a scale | Standard Deviation 0.7988086 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I try to change my speech to sound different | 1.0666667 score on a scale | Standard Deviation 0.2581989 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | My articulation is unclear | 1.4666667 score on a scale | Standard Deviation 0.7432234 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | The intelligibility is unpredictable | 1.1333333 score on a scale | Standard Deviation 0.3518658 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I feel ask though I have to strain to speak | 1.2000000 score on a scale | Standard Deviation 0.5606119 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | People ask me why I'm hard to understand | 1.1333333 score on a scale | Standard Deviation 0.3518658 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by Speech Handicap Index | I run out of air when I speak | 1.2666667 score on a scale | Standard Deviation 0.7037316 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I'm tense when talking to others because of my speech | 1.6666667 score on a scale | Standard Deviation 1.0327956 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I find other people don't understand my speaking problem | 1.3333333 score on a scale | Standard Deviation 0.5163978 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My speaking difficulties restrict my person and social life | 1.5000000 score on a scale | Standard Deviation 0.83666 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I have difficulties to continue a conversation because of my speech | 1.8571429 score on a scale | Standard Deviation 1.069045 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | The intelligibility is unpredictable | 1.5000000 score on a scale | Standard Deviation 0.83666 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I avoid using the phone | 1.6666667 score on a scale | Standard Deviation 1.0327956 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My speech makes it difficult for people to understand me | 1.8333333 score on a scale | Standard Deviation 1.3291601 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I feel left out of conversations because of my speech | 1.4285714 score on a scale | Standard Deviation 0.7867958 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | How do you rate your own speech at this moment? | 1.5714286 score on a scale | Standard Deviation 0.7867958 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I use a great deal of effort to speak | 1.8571429 score on a scale | Standard Deviation 1.069045 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I feel annoyed when people ask me to repeat | 1.6666667 score on a scale | Standard Deviation 1.0327956 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My speech is worse in the evening | 1.8571429 score on a scale | Standard Deviation 0.8997354 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I feel embarrassed when people ask me to repeat | 1.2857143 score on a scale | Standard Deviation 0.48795 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My speech problem causes me to lose income | 1.4285714 score on a scale | Standard Deviation 0.7867958 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | People ask me why I'm hard to understand | 1.3333333 score on a scale | Standard Deviation 0.5163978 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I try to change my speech to sound different | 1.2857143 score on a scale | Standard Deviation 0.7559289 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My speech makes me feel incompetent | 1.5000000 score on a scale | Standard Deviation 0.83666 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My speech problem upsets me | 1.8571429 score on a scale | Standard Deviation 1.069045 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I am less outgoing because of my speech problem | 1.4285714 score on a scale | Standard Deviation 0.7867958 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | The intelligibility of my speech varies throughout the day | 1.8333333 score on a scale | Standard Deviation 1.3291601 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My family has difficulty understanding me when I call them throughout the house | 1.5714286 score on a scale | Standard Deviation 0.9759001 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I tend to avoid groups of people because of my speech | 1.8333333 score on a scale | Standard Deviation 1.3291601 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | People have difficulty understanding me in a noisy room | 1.8333333 score on a scale | Standard Deviation 0.9831921 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I'm ashamed of my speech problem | 1.2857143 score on a scale | Standard Deviation 0.48795 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | People seem irritated with my speech | 1.5000000 score on a scale | Standard Deviation 0.83666 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | People ask me to repeat myself when speaking face-to-face | 1.8333333 score on a scale | Standard Deviation 0.9831921 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My articulation is unclear | 1.8333333 score on a scale | Standard Deviation 1.3291601 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | My speech makes me feel handicapped | 1.5714286 score on a scale | Standard Deviation 0.9759001 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I speak with friends and neighbors and relatives less often because of my speech | 1.5000000 score on a scale | Standard Deviation 0.83666 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I run out of air when I speak | 1.8333333 score on a scale | Standard Deviation 1.3291601 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by Speech Handicap Index | I feel ask though I have to strain to speak | 2.0000000 score on a scale | Standard Deviation 1.2649111 |
Secondary
Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory
* Each item is scored on a 5 point Likert scale (strongly disagree, disagree, no opinion, agree, strongly agree). Strongly agree = 1, Disagree = 2, No opinion = 3, Agree = 4, and Strongly Agree = 5 * The lower the score the lower the quality of life
Time frame: Baseline, 1 month, 6 months, 12 months, and 24 months
Population: Some participants were not analyzed as the participants did not complete the questionnaires.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing ability limits my day to day activities. | 3.2608696 score on a scale | Standard Deviation 1.3888318 |
| Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Other people are irritated by my eating problem. | 4.2608696 score on a scale | Standard Deviation 0.8643122 |
| Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am embarrassed by my eating habits. | 3.5454545 score on a scale | Standard Deviation 1.2993505 |
| Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People ask me, Why can't you eat that? | 4.0869565 score on a scale | Standard Deviation 1.1246431 |
| Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not go out because of my swallowing problem. | 3.9130435 score on a scale | Standard Deviation 0.9960396 |
| Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People have difficulty cooking for me. | 3.2173913 score on a scale | Standard Deviation 1.5062452 |
| Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am upset by my swallowing problem. | 3.2272727 score on a scale | Standard Deviation 1.6599431 |
| Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing difficulty has caused me to lose income. | 4.2608696 score on a scale | Standard Deviation 1.0538842 |
| Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing is more difficult at the end of the day. | 3.3636364 score on a scale | Standard Deviation 1.4974726 |
| Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | It takes me longer to eat because of my swallowing problem. | 2.5909091 score on a scale | Standard Deviation 1.4690162 |
| Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not feel self-conscious when I eat. | 3.3913043 score on a scale | Standard Deviation 1.3395769 |
| Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing takes great effort. | 3.0869565 score on a scale | Standard Deviation 1.5049326 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not feel self-conscious when I eat. | 4.0909091 score on a scale | Standard Deviation 1.2210279 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am upset by my swallowing problem. | 2.0909091 score on a scale | Standard Deviation 1.5135749 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing takes great effort. | 3.4545455 score on a scale | Standard Deviation 1.2135598 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Other people are irritated by my eating problem. | 4.2727273 score on a scale | Standard Deviation 1.00905 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am embarrassed by my eating habits. | 4.4545455 score on a scale | Standard Deviation 0.8201995 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing ability limits my day to day activities. | 4.0000000 score on a scale | Standard Deviation 1.0954451 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People have difficulty cooking for me. | 3.9090909 score on a scale | Standard Deviation 1.2210279 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not go out because of my swallowing problem. | 4.6363636 score on a scale | Standard Deviation 0.504525 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing is more difficult at the end of the day. | 4.5454545 score on a scale | Standard Deviation 0.6875517 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | It takes me longer to eat because of my swallowing problem. | 2.4000000 score on a scale | Standard Deviation 1.4298407 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing difficulty has caused me to lose income. | 3.9090909 score on a scale | Standard Deviation 1.7002674 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People ask me, Why can't you eat that? | 4.0000000 score on a scale | Standard Deviation 1.1547005 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing ability limits my day to day activities. | 4.1818182 score on a scale | Standard Deviation 1.2203186 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not feel self-conscious when I eat. | 3.9090909 score on a scale | Standard Deviation 1.1087999 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing is more difficult at the end of the day. | 3.8095238 score on a scale | Standard Deviation 1.3273676 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing difficulty has caused me to lose income. | 4.5000000 score on a scale | Standard Deviation 0.7400129 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am upset by my swallowing problem. | 2.8636364 score on a scale | Standard Deviation 1.6123173 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am embarrassed by my eating habits. | 4.1818182 score on a scale | Standard Deviation 1.2587357 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Other people are irritated by my eating problem. | 4.5454545 score on a scale | Standard Deviation 0.7385489 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing takes great effort. | 3.9545455 score on a scale | Standard Deviation 1.0455016 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not go out because of my swallowing problem. | 4.3181818 score on a scale | Standard Deviation 0.9454837 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People have difficulty cooking for me. | 3.7727273 score on a scale | Standard Deviation 1.3777766 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | It takes me longer to eat because of my swallowing problem. | 3.1818182 score on a scale | Standard Deviation 1.5625487 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People ask me, Why can't you eat that? | 4.0000000 score on a scale | Standard Deviation 1.2344268 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am upset by my swallowing problem. | 2.6363636 score on a scale | Standard Deviation 1.361817 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not go out because of my swallowing problem. | 4.1818182 score on a scale | Standard Deviation 0.9816498 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing ability limits my day to day activities. | 4.1818182 score on a scale | Standard Deviation 1.1677484 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am embarrassed by my eating habits. | 4.4545455 score on a scale | Standard Deviation 0.522233 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People ask me, Why can't you eat that? | 3.7272727 score on a scale | Standard Deviation 1.3483997 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing is more difficult at the end of the day. | 4.0909091 score on a scale | Standard Deviation 0.9438798 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Other people are irritated by my eating problem. | 4.3636364 score on a scale | Standard Deviation 0.8090398 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not feel self-conscious when I eat. | 4.1818182 score on a scale | Standard Deviation 0.9816498 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | It takes me longer to eat because of my swallowing problem. | 2.9090909 score on a scale | Standard Deviation 1.7002674 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People have difficulty cooking for me. | 4.2727273 score on a scale | Standard Deviation 1.00905 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing takes great effort. | 3.9090909 score on a scale | Standard Deviation 1.2210279 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing difficulty has caused me to lose income. | 4.3636364 score on a scale | Standard Deviation 0.8090398 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am embarrassed by my eating habits. | 4.3846154 score on a scale | Standard Deviation 1.1208971 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People ask me, Why can't you eat that? | 4.1538462 score on a scale | Standard Deviation 1.2810252 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not feel self-conscious when I eat. | 4.3846154 score on a scale | Standard Deviation 0.9607689 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not go out because of my swallowing problem. | 4.5384615 score on a scale | Standard Deviation 0.877058 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing takes great effort. | 3.6923077 score on a scale | Standard Deviation 1.315587 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People have difficulty cooking for me. | 3.7692308 score on a scale | Standard Deviation 1.4806444 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing ability limits my day to day activities. | 4.3076923 score on a scale | Standard Deviation 0.9473309 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing difficulty has caused me to lose income. | 4.6153846 score on a scale | Standard Deviation 0.6504436 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | It takes me longer to eat because of my swallowing problem. | 3.0769231 score on a scale | Standard Deviation 1.4978617 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Other people are irritated by my eating problem. | 4.6923077 score on a scale | Standard Deviation 0.6304252 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am upset by my swallowing problem. | 3.1538462 score on a scale | Standard Deviation 1.675617 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing is more difficult at the end of the day. | 4.6153846 score on a scale | Standard Deviation 0.8697185 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am upset by my swallowing problem. | 2.2857143 score on a scale | Standard Deviation 1.2535663 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing is more difficult at the end of the day. | 3.8571429 score on a scale | Standard Deviation 1.069045 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People ask me, Why can't you eat that? | 3.4285714 score on a scale | Standard Deviation 1.1338934 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People have difficulty cooking for me. | 3.1428571 score on a scale | Standard Deviation 1.2149858 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am embarrassed by my eating habits. | 3.8571429 score on a scale | Standard Deviation 0.6900656 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Other people are irritated by my eating problem. | 3.8571429 score on a scale | Standard Deviation 0.6900656 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing ability limits my day to day activities. | 3.5714286 score on a scale | Standard Deviation 1.5118579 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not go out because of my swallowing problem. | 3.8571429 score on a scale | Standard Deviation 1.069045 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing takes great effort. | 3.0000000 score on a scale | Standard Deviation 1.1547005 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing difficulty has caused me to lose income. | 4.0000000 score on a scale | Standard Deviation 1.1547005 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | It takes me longer to eat because of my swallowing problem. | 2.1428571 score on a scale | Standard Deviation 0.8997354 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not feel self-conscious when I eat. | 3.7142857 score on a scale | Standard Deviation 1.1126973 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing is more difficult at the end of the day. | 4.2857143 score on a scale | Standard Deviation 1.1387288 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing ability limits my day to day activities. | 4.5000000 score on a scale | Standard Deviation 0.6504436 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am embarrassed by my eating habits. | 4.4285714 score on a scale | Standard Deviation 0.7559289 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not feel self-conscious when I eat. | 4.0769231 score on a scale | Standard Deviation 1.3204506 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am upset by my swallowing problem. | 2.7857143 score on a scale | Standard Deviation 1.6723347 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People have difficulty cooking for me. | 4.2142857 score on a scale | Standard Deviation 1.1883131 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing takes great effort. | 3.9285714 score on a scale | Standard Deviation 1.384768 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not go out because of my swallowing problem. | 4.6428571 score on a scale | Standard Deviation 0.6333237 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing difficulty has caused me to lose income. | 4.6428571 score on a scale | Standard Deviation 0.6333237 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | It takes me longer to eat because of my swallowing problem. | 3.5000000 score on a scale | Standard Deviation 1.6052798 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People ask me, Why can't you eat that? | 4.2142857 score on a scale | Standard Deviation 1.1883131 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Other people are irritated by my eating problem. | 4.5714286 score on a scale | Standard Deviation 0.7559289 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Other people are irritated by my eating problem. | 4.1428571 score on a scale | Standard Deviation 0.8997354 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | It takes me longer to eat because of my swallowing problem. | 3.0000000 score on a scale | Standard Deviation 1.9148542 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing takes great effort. | 3.1428571 score on a scale | Standard Deviation 1.5735916 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am embarrassed by my eating habits. | 3.1428571 score on a scale | Standard Deviation 1.2149858 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing is more difficult at the end of the day. | 4.1428571 score on a scale | Standard Deviation 1.069045 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not feel self-conscious when I eat. | 3.7142857 score on a scale | Standard Deviation 1.2535663 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People have difficulty cooking for me. | 3.7142857 score on a scale | Standard Deviation 1.3801311 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing ability limits my day to day activities. | 3.2857143 score on a scale | Standard Deviation 1.6035675 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not go out because of my swallowing problem. | 4.1428571 score on a scale | Standard Deviation 1.069045 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am upset by my swallowing problem. | 3.1428571 score on a scale | Standard Deviation 1.3451854 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People ask me, Why can't you eat that? | 3.0000000 score on a scale | Standard Deviation 1.6329932 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing difficulty has caused me to lose income. | 3.8571429 score on a scale | Standard Deviation 1.2149858 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing takes great effort. | 3.5625000 score on a scale | Standard Deviation 1.263263 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing difficulty has caused me to lose income. | 4.6000000 score on a scale | Standard Deviation 0.6324555 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am upset by my swallowing problem. | 3.0625000 score on a scale | Standard Deviation 1.7308476 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not feel self-conscious when I eat. | 3.6875000 score on a scale | Standard Deviation 1.3022417 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | It takes me longer to eat because of my swallowing problem. | 2.8750000 score on a scale | Standard Deviation 1.5438048 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing is more difficult at the end of the day. | 4.4000000 score on a scale | Standard Deviation 0.910259 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am embarrassed by my eating habits. | 4.1250000 score on a scale | Standard Deviation 1.2041595 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Other people are irritated by my eating problem. | 4.3750000 score on a scale | Standard Deviation 0.8062258 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People ask me, Why can't you eat that? | 4.1875000 score on a scale | Standard Deviation 1.3275918 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing ability limits my day to day activities. | 3.9375000 score on a scale | Standard Deviation 1.3889444 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People have difficulty cooking for me. | 3.9375000 score on a scale | Standard Deviation 1.3400871 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not go out because of my swallowing problem. | 4.1875000 score on a scale | Standard Deviation 1.0468206 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not go out because of my swallowing problem. | 4.2500000 score on a scale | Standard Deviation 0.8864053 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People ask me, Why can't you eat that? | 4.5000000 score on a scale | Standard Deviation 0.9258201 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing ability limits my day to day activities. | 4.6250000 score on a scale | Standard Deviation 0.5175492 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing takes great effort. | 3.3750000 score on a scale | Standard Deviation 1.407886 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am upset by my swallowing problem. | 3.2500000 score on a scale | Standard Deviation 1.4880476 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Other people are irritated by my eating problem. | 4.3750000 score on a scale | Standard Deviation 0.9161254 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | Swallowing is more difficult at the end of the day. | 4.7500000 score on a scale | Standard Deviation 0.46291 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I am embarrassed by my eating habits. | 4.1250000 score on a scale | Standard Deviation 0.6408699 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | People have difficulty cooking for me. | 4.1250000 score on a scale | Standard Deviation 0.6408699 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | It takes me longer to eat because of my swallowing problem. | 3.1250000 score on a scale | Standard Deviation 1.6420806 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | My swallowing difficulty has caused me to lose income. | 4.5000000 score on a scale | Standard Deviation 0.7559289 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by the MD Anderson Dysphagia Inventory | I do not feel self-conscious when I eat. | 4.5000000 score on a scale | Standard Deviation 0.7559289 |
Secondary
Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire
* It contains 8 questions regarding dryness either during feeding or in the unstimulated state. Participants rate each item from 0 to 10, where 10 indicates the maximum dryness or discomfort due to dryness. * The higher the score the worse the participant's xerostomia
Time frame: Baseline, 1 month, 6 months, 12 months, and 24 months
Population: Some participants were not analyzed as the participants did not complete the questionnaires.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness while not eating | 2.1250000 score on a scale | Standard Deviation 2.1931217 |
| Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in swallowing solid food due to dryness | 2.6956522 score on a scale | Standard Deviation 2.6532104 |
| Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids to aid swallowing food | 3.1739130 score on a scale | Standard Deviation 2.7741039 |
| Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in talking due to dryness | 2.3333333 score on a scale | Standard Deviation 2.4788964 |
| Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty chewing due to dryness | 2.3913043 score on a scale | Standard Deviation 2.2711457 |
| Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness when eating food | 2.2173913 score on a scale | Standard Deviation 2.1523037 |
| Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of your sleeping problems due to dryness | 1.7916667 score on a scale | Standard Deviation 1.8876985 |
| Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids for oral comfort when not eating | 2.9565217 score on a scale | Standard Deviation 2.7216015 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness while not eating | 1.5454545 score on a scale | Standard Deviation 2.3393861 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness when eating food | 1.8181818 score on a scale | Standard Deviation 3.0271499 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in swallowing solid food due to dryness | 1.6363636 score on a scale | Standard Deviation 2.8380531 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids to aid swallowing food | 2.2727273 score on a scale | Standard Deviation 3.1013194 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty chewing due to dryness | 1.4545455 score on a scale | Standard Deviation 2.5831623 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of your sleeping problems due to dryness | 1.5454545 score on a scale | Standard Deviation 2.8412545 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids for oral comfort when not eating | 2.0909091 score on a scale | Standard Deviation 2.8090762 |
| Radiotherapy, Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in talking due to dryness | 1.3636364 score on a scale | Standard Deviation 2.2033033 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in swallowing solid food due to dryness | 3.4285714 score on a scale | Standard Deviation 2.5994505 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness while not eating | 3.8571429 score on a scale | Standard Deviation 2.7979584 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness when eating food | 3.8571429 score on a scale | Standard Deviation 2.9203718 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids to aid swallowing food | 5.1428571 score on a scale | Standard Deviation 3.2293299 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of your sleeping problems due to dryness | 3.2857143 score on a scale | Standard Deviation 2.9179249 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in talking due to dryness | 2.8095238 score on a scale | Standard Deviation 2.9089353 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids for oral comfort when not eating | 4.6190476 score on a scale | Standard Deviation 3.338805 |
| 1 Month - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty chewing due to dryness | 3.5238095 score on a scale | Standard Deviation 2.6947922 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness when eating food | 3.7272727 score on a scale | Standard Deviation 3.2277208 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids to aid swallowing food | 4.0000000 score on a scale | Standard Deviation 3.4351128 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids for oral comfort when not eating | 3.3636364 score on a scale | Standard Deviation 2.9076701 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in talking due to dryness | 3.9090909 score on a scale | Standard Deviation 2.3855626 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty chewing due to dryness | 3.1818182 score on a scale | Standard Deviation 2.8219916 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in swallowing solid food due to dryness | 3.9000000 score on a scale | Standard Deviation 2.9608557 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness while not eating | 3.0909091 score on a scale | Standard Deviation 2.1191765 |
| 1 Month - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of your sleeping problems due to dryness | 3.0000000 score on a scale | Standard Deviation 2.8982753 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids for oral comfort when not eating | 3.4285714 score on a scale | Standard Deviation 3.1553199 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in swallowing solid food due to dryness | 3.5000000 score on a scale | Standard Deviation 2.9807072 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness while not eating | 2.6428571 score on a scale | Standard Deviation 2.8177226 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids to aid swallowing food | 5.0000000 score on a scale | Standard Deviation 2.6602487 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty chewing due to dryness | 3.0714286 score on a scale | Standard Deviation 2.4326082 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in talking due to dryness | 3.0000000 score on a scale | Standard Deviation 2.9612887 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of your sleeping problems due to dryness | 1.7142857 score on a scale | Standard Deviation 2.0542104 |
| 6 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness when eating food | 3.5000000 score on a scale | Standard Deviation 2.8216198 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in talking due to dryness | 4.8571429 score on a scale | Standard Deviation 3.2366944 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty chewing due to dryness | 4.5714286 score on a scale | Standard Deviation 3.5523299 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids for oral comfort when not eating | 5.2857143 score on a scale | Standard Deviation 2.7516229 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness while not eating | 4.7142857 score on a scale | Standard Deviation 2.4976179 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in swallowing solid food due to dryness | 5.2857143 score on a scale | Standard Deviation 3.545621 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness when eating food | 5.7142857 score on a scale | Standard Deviation 3.0394235 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids to aid swallowing food | 6.7142857 score on a scale | Standard Deviation 2.6903708 |
| 6 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of your sleeping problems due to dryness | 4.4285714 score on a scale | Standard Deviation 2.8199966 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in swallowing solid food due to dryness | 3.3750000 score on a scale | Standard Deviation 3.0304015 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids to aid swallowing food | 5.0625000 score on a scale | Standard Deviation 3.5864328 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty chewing due to dryness | 2.6250000 score on a scale | Standard Deviation 2.2766935 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness while not eating | 3.2500000 score on a scale | Standard Deviation 2.7446918 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of your sleeping problems due to dryness | 2.2500000 score on a scale | Standard Deviation 2.2656861 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness when eating food | 3.5000000 score on a scale | Standard Deviation 3.0767949 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids for oral comfort when not eating | 3.8750000 score on a scale | Standard Deviation 3.4229617 |
| 12 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in talking due to dryness | 2.5625000 score on a scale | Standard Deviation 2.8276905 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness when eating food | 4.0000000 score on a scale | Standard Deviation 3.6968455 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids for oral comfort when not eating | 3.7142857 score on a scale | Standard Deviation 3.7733401 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in talking due to dryness | 3.5714286 score on a scale | Standard Deviation 3.2071349 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids to aid swallowing food | 5.0000000 score on a scale | Standard Deviation 3.6968455 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in swallowing solid food due to dryness | 4.1428571 score on a scale | Standard Deviation 3.5321651 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness while not eating | 3.4285714 score on a scale | Standard Deviation 3.4572216 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty chewing due to dryness | 3.7142857 score on a scale | Standard Deviation 3.8606686 |
| 12 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of your sleeping problems due to dryness | 3.5714286 score on a scale | Standard Deviation 3.101459 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness when eating food | 3.8750000 score on a scale | Standard Deviation 3.0523215 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids to aid swallowing food | 5.3125000 score on a scale | Standard Deviation 3.2397274 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids for oral comfort when not eating | 4.0000000 score on a scale | Standard Deviation 3.4448028 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in talking due to dryness | 3.6875000 score on a scale | Standard Deviation 2.9825884 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty chewing due to dryness | 3.6250000 score on a scale | Standard Deviation 2.9183329 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in swallowing solid food due to dryness | 4.1250000 score on a scale | Standard Deviation 2.8722813 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of your sleeping problems due to dryness | 2.6000000 score on a scale | Standard Deviation 2.8485585 |
| 24 Months - Radiotherapy | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness while not eating | 3.7500000 score on a scale | Standard Deviation 3.1517191 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty chewing due to dryness | 2.7500000 score on a scale | Standard Deviation 2.6592158 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of your sleeping problems due to dryness | 2.7500000 score on a scale | Standard Deviation 2.4348658 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in swallowing solid food due to dryness | 3.2500000 score on a scale | Standard Deviation 3.0118812 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your difficulty in talking due to dryness | 3.1250000 score on a scale | Standard Deviation 2.7998724 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids to aid swallowing food | 4.1250000 score on a scale | Standard Deviation 3.6815175 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness while not eating | 2.6250000 score on a scale | Standard Deviation 2.7222627 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate the frequency of sipping liquids for oral comfort when not eating | 2.7500000 score on a scale | Standard Deviation 3.3273756 |
| 24 Months - Radiotherapy + Cisplatin | Change in Quality of Life as Measured by University of Michigan Xerostomia Questionnaire | Rate your mouth or throat dryness when eating food | 3.3750000 score on a scale | Standard Deviation 3.0207615 |
Secondary
Disease Specific Survival
Time frame: 1 year
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Radiotherapy | Disease Specific Survival | 24 Participants |
| Radiotherapy, Cisplatin | Disease Specific Survival | 10 Participants |
Secondary
Number of Complications/Acute Toxicity by Organ Class
-Assessed by the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 4.0.
Time frame: Approximately 18 weeks
Population: One participant in each Arm did not have adverse events collected.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | General disorders | 38 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Metabolism and nutrition disorders | 11 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Eye disorders | 2 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Musculoskeletal and connective tissue disorders | 15 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Immune system disorders | 1 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Neoplasms benign, malignant and unspecified (incl cysts and polyps) | 1 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Ear and labyrinth disorders | 11 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Nervous system disorders | 48 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Infections and infestations | 7 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Psychiatric disorders | 16 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Gastrointestinal disorders | 104 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Respiratory, thoracic and mediastinal disorders | 34 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Injury, poisoning and procedureal complications | 31 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Skin and subcutaneous tissue disorders | 32 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Cardiac disorders | 0 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Surgical and medical procedures | 3 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Investigations | 20 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Vascular disorders | 11 number of adverse events |
| Radiotherapy | Number of Complications/Acute Toxicity by Organ Class | Blood and lymphatic system disorders | 5 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Vascular disorders | 6 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Blood and lymphatic system disorders | 12 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Cardiac disorders | 1 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Ear and labyrinth disorders | 4 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Eye disorders | 0 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Gastrointestinal disorders | 61 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | General disorders | 17 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Immune system disorders | 0 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Infections and infestations | 2 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Injury, poisoning and procedureal complications | 9 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Investigations | 60 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Metabolism and nutrition disorders | 26 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Musculoskeletal and connective tissue disorders | 9 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Neoplasms benign, malignant and unspecified (incl cysts and polyps) | 0 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Nervous system disorders | 29 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Psychiatric disorders | 9 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Respiratory, thoracic and mediastinal disorders | 14 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Skin and subcutaneous tissue disorders | 14 number of adverse events |
| Radiotherapy, Cisplatin | Number of Complications/Acute Toxicity by Organ Class | Surgical and medical procedures | 0 number of adverse events |
Secondary
Rate of Distant Metastasis
Assessed by biopsy or imaging-detected recurrent disease at sites away from the original primary and cervical zone.
Time frame: Up to 2 years
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Radiotherapy | Rate of Distant Metastasis | 2 Participants |
| Radiotherapy, Cisplatin | Rate of Distant Metastasis | 0 Participants |