Influence of Inspiratory Flow Pattern on Exchange of Carbon Dioxide in Humans Without Primary Lung Disease

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01686984

Enrollment

Registered

2012-09-18

Start date

2012-09-30

Completion date

2015-05-31

Last updated

2015-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carbon Dioxide, Pulmonary Gas Exchange

Brief summary

The purpose of this study is to investigate how inspiratory flow pattern influences CO2 elimination in people without primary lung disease. The hypothesis is that a long mean distribution time, caused by a long postinspiratory pause and high end-inspiratory flow, will promote CO2 exchange in the alveoli.

Interventions

OTHERAltered breath

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* No known primary lung disease

Exclusion criteria

* Primary lung disease

Design outcomes

Primary

Measure	Time frame
Carbon dioxide elimination in a ventilator assisted breath.	30 minutes

Secondary

Measure	Time frame
Blood CO2 concentration.	30 minutes

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 12, 2026