Hypogeusia
Conditions
Keywords
Taste, Fat Taste, Threshold Testing
Brief summary
This study will examine whether or not short, daily exposures change a person's ability to detect free fatty acids in a solution by its taste. Repeated exposure should improve a person's ability to detect free fatty acids.
Detailed description
The possibility that humans can taste non-esterified fatty acids (NEFA) - so-called fat taste - is a relatively new area of research. Previous work suggests that subjects require an average of between two and three testing sessions of approximately an hour each before they can reliably detect NEFA, and the average number of visits to get the lowest threshold is six. Streamlining this process is of great interest to researchers who wish to test many people as quickly as possible. Other taste qualities, including umami and sweet, have shown improvement in detection sensitivity in subjects that have undergone ten second exposures to these taste qualities for 10 days upon subsequent re-testing. We seek to determine if the same improvements can be seen with fat taste.
Interventions
OTHERNEFA
OTHERSucrose
Sponsors
Purdue University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* good health * available for multiple testing visits
Exclusion criteria
* have participated in a fat taste study in the past 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NEFA detection threshold | 10 days |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hunger | 2 days | Visual analog scale assessment of hunger level prior to testing |
| BMI | 1 day | — |
| Taste descriptor | 10 days | Description of NEFA taste by participant, e.g., sour, bitter, etc. |
Countries
United States
Outcome results
None listed