CT-angiographic Follow up of Patients That Underwent Coronary Bypass Surgery Between 1993-1997

CT-angiographic Follow Upp of Patients That Underwent Coronary Bypass Surgery Between 1993-1997. A Randomized Longitudinal Trial.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01686100

Enrollment

Registered

2012-09-17

Start date

2010-06-30

Completion date

2011-11-30

Last updated

2012-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

Coronary artery bypass grafting, Saphenous vein grafts

Brief summary

Coronary artery surgery (CABG) is necessary to improve blood circulation in many patients with coronary artery disease. This is done by using alternative blood vessels (grafts) to bypass the stenosed coronary arteries. In CABG, vein grafts are traditionally used where surrounding tissue is removed, this may damage the vessel and influence its patency. The no-touch technique was developed by Professor Domingos Souza at the Department of Cardiovascular and Thoracic Surgery, Örebro University Hospital. This technique includes taking out the vein with its surrounding tissue and by this way the vessel is less damaged. The first two follow ups have shown that no-touch grafts had better patency than conventionally extracted graft at 18 months and 8.5 years. This long term follow up is a continuation of the randomized trial started in 1993 where the patency and incidence of stenoses in the no touch and conventional vein grafts has been studied.

Interventions

PROCEDURENo touch technique

The vein graft is harvested with its surronding tissues.

PROCEDUREConventional technique

The vein graft is stripped from its surrounding tissues.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Investigator)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

1. First time coronary artery bypass grafting with either conventional or no touch vein grafts performed by Dr.Souza between 1993-1997. 2. Included in the previous follow up studies 3. Signed and dated consent.

Exclusion criteria

1. Allergy to contrast 2. Renal failure 3. Uncontrolled diabetes 4. Unable to implement the study according to protocol -

Design outcomes

Primary

Measure	Time frame
Patency of the grafts	Mean time of 15 years.

Secondary

Measure	Time frame
Stenosis in the grafts.	Mean time of 15 years.

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 5, 2026