Grass Sensitisation and Allergic Rhinitis in Thai Patients

The Study of Allergens From Grass and Weed Which Are Causes of Allergic Rhinitis in Thai Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01686022

Enrollment

Registered

2012-09-17

Start date

2012-10-31

Completion date

2015-10-31

Last updated

2016-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic Rhinitis Due to Weed Pollens, Allergy to Grass Pollen

Keywords

Grass, Major allergen, cross-reactivity

Brief summary

Allergic rhinitis patients are the patients who have nasal symptoms when triggered by indoor or outdoor allergens. Outdoor allergen can be divided into grass, tree, or weed. The type of grass or weed are different in various part of the world. The allergens from grass and weed has never been studied in Thailand. This study will find the major allergen from Bermuda grass, Johnson grass, Para grass, sedge, and ragweed, which are very common in Thailand. In addition, the investigators will study about the cross-reactivity among these group of allergen.

Detailed description

To find the major allergen of grass and weed, the serum of patients will be used to bind with the allergen extract by immunoblot study. The ELISA-inhibition will be used to study about cross-reactivity among various kinds of grass and weed.

Interventions

OTHERImmunoblot

serum specific IgE binds to grass extract by immunoblot

Eligibility

Sex/Gender

ALL

Age

10 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Allergic rhinitis patients age 10-50 years old * Control: healthy volunteer age 18-50 years old

Exclusion criteria

* Chronic illness such as cardiovascular diseases, liver diseases * History of anaphylaxis * Pregnancy

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026