Comparison of Same-day 2 Sachets Picosulfate Versus High Volume PEG for Afternoon Colonoscopy

Comparison of Using the Same-day 2 Sachets Picosulfate Versus High Volume PEG Bowel Preparation for Afternoon Colonoscopy

Status

UNKNOWN

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01685970

Acronym

SP2HP

Enrollment

200

Registered

2012-09-17

Start date

2012-09-30

Completion date

2012-11-30

Last updated

2012-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colonoscopy

Keywords

Bowel preparation, colonoscopy, polyethylene glycol, picosulfate

Brief summary

Comparison of using the same-day 2 sachets picosulfate versus high volume PEG bowel preparation for afternoon colonoscopy Morning only same-day 2 sachets picosulfate may enhance patient tolerability and have similar bowel cleansing efficacy compared to standard method using high volume split-dose PEG. The investigators aimed to evaluate the efficacy and tolerability of bowel preparation protocols with same-day 2 sachets picosulfate compared to conventional high volume (4L) split-dose for afternoon colonoscopy.

Detailed description

Split-dose PEG (4L) regimens is a standard regimen for bowel preparation because it has better preparation quality and tolerability than single dose 4L PEG regimens. However, although patients drink each 2L separately, the total volume of 4 L PEG is still quite burdensome volume to ingest. In addition, in split dose method, night dose of day before the procedure make patient to suffer from sleep disturbance because of frequent diarrhea and abdominal discomfort. The investigators aimed to evaluate the efficacy and tolerability of bowel preparation protocols with same-day 2 sachets picosulfate compared to conventional high volume (4L) split-dose for afternoon colonoscopy.

Interventions

DRUGHigh volume split-dose PEG

High volume split-dose PEG 2L/2L 2 times before the day and at the day of colonoscopy

DRUG2 sachets of picosulfate

2 sachets of picosulfate 2 times for bowel preparation at the day of colonoscopy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

SINGLE (Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Adult outpatients who undergo afternoon colonoscopy for screening, surveillance or with symptoms

Exclusion criteria

* pregnancy, * breast feeding, * prior history of surgical large bowel resection, * severe medical condition such as severe cardiac, * hepatic, or * renal failure (creatinine ≥ 3.0 mg/dL (normal 0.8-1.4 mg/dL)), * significant gastric paresis or gastric outlet obstruction or ileus, * known or suspected bowel obstruction or perforation, * drug addiction or major psychiatric illness, * allergy to PEG and refusal to participate in the study

Design outcomes

Primary

Measure	Time frame	Description
Quality of bowel preparation	3 months	Quality of bowel preparation using Ottawa bowel preparation scale

Secondary

Measure	Time frame	Description
Tolerability	3 months	Tolerability of bowel preparation regimen is assessed by patient questionnaire.

Countries

South Korea

Contacts

Primary ContactTae Oh Kim, Ph D.

kto0440@paik.ac.kr82-51-797-0658

Backup ContactEun Hee Seo, MD

arate98@naver.com82-51-797-0220

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026