Heart Valve Diseases
Conditions
Keywords
perfusion, cardiopulmonary bypass, hypothermia, cerebral oxygenation
Brief summary
The aim of our study was to evaluate the effect of different temperature regimens of cardiopulmonary bypass on systemic oxygen transport and cerebral oxygenation during surgical correction of acquired heart diseases.
Detailed description
Our aim was to evaluate the effect of hypothermic and normothermic regimens of cardiopulmonary bypass on systemic oxygen transport and cerebral oxygenation during valve surgery
Interventions
DEVICEhypothermic CPB
maintenance of mild hypothermia during cardiopulmonary bypass
DEVICEnormothermic CPB
maintenance of normal body temperature during cardiopulmonary bypass
Sponsors
Northern State Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* requirement of surgical correction of two or more valves
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cerebral oxygen saturation | perioperatively | measurement of cerebral oxygen saturation during cardiopulmonary bypass and 24 hrs postoperatively |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| time until fit for ICU discharge fulfillment | 5 days postoperatively | measurement of time to fulfillment of the fit for discharge criteria |
Countries
Russia
Outcome results
None listed