Immature Myeloid Cells in Respiratory Syncytial Virus Bronchioliltis

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01684527

Enrollment

Registered

2012-09-13

Start date

2012-10-31

Completion date

2014-01-31

Last updated

2012-09-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchiolitis

Brief summary

The investigators hypothesize that Respiratory Syncytial Virus (RSV) infection may influence the population of lung immature myeloid cells and dendritic cells in a way that will impair their ability to invoke an effective immune response and lead to prolonged inflammation, angiogenesis and scarring. This may lead in turn to disturbed lung function. Our aim is to determine the presence and phenotype of immature myeloid cells present in respiratory secretions of children with RSV bronchiolitis as compared to non-RSV bronchiolitis and healthy controls.

Interventions

OTHERRespiratory secretions obtained

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 2 Years

Healthy volunteers

Yes

Inclusion criteria

* Bronchiolitis

Exclusion criteria

* Chronic disease

Design outcomes

Primary

Measure	Time frame	Description
Number of Immature Myeloid Cells in Respiratory Secretions	Participants will be followed for the duration of hospital stay, an expected average of one week	Respiratory secretions obtained from child presenting with bronchiolitis will be examined for the presence of immature myeloid cells

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026