Postprandial, Hyperglycemia, Postprandial, Feeding Behaviors, Antioxidant, Lipid Profile
Conditions
Keywords
Antioxidant, glucose metabolism, jam, polyphenols, postprandial, strawberry
Brief summary
The aim of this study is to investigate the effects of an acute intake of three different types of strawberry jam, differing in the carbohydrates and antioxidants content, on postprandial glucose metabolism, lipid profile, antioxidant status and satiety indices, in healthy adults.
Detailed description
Study Design: Randomized, postprandial, crossover, double-blind intervention with three arms. Subjects: Sixteen healthy adults Product studied: At each arm, participants consume 60g of strawberry jam: * High-sugar jam (traditional; HS), * Low-sugar jam (without added-sugar; LS), * Low-sugar jam including antioxidant extract from strawberry pulp (LSA).
Interventions
OTHERStrawberry Jam
Sponsors
Clinica Universidad de Navarra, Universidad de Navarra
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Adult men and women * Normal weight or overweight (BMI between 18.5 and 29.9 kg/m2) * Age between 20 and 50 years old.
Exclusion criteria
* To suffer from any chronic disease related to metabolism, * To follow concomitant medications, * To follow slimming treatments or hormone replacement therapy, * To have any inability to perform the follow-up, * Smoking, * Known food allergies, * Pregnancy, lactation or menopause
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Plasma malondialdehyde (MDA) postprandial measure | up to 120 minutes | Plasma MDA measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Serum insulin postprandial concentration | baseline, 30, 60, 90 and 120 minutes | Serum insulin measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam |
| HOMA insulin resistance index | Baseline, 30, 60, 90 and 120 minutes | HOMA-IR calculated at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam |
| Serum total cholesterol postprandial concentration | Baseline, 30, 60, 90 and 120 minutes | Serum total cholesterol measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam |
| Serum HDL-cholesterol postprandial concentration | Baseline, 30, 60, 90 and 120 minutes | Serum HDL-cholesterol measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam |
| Serum glucose postprandial concentration | Baseline, 30, 60, 90 and 120 minutes | Serum Glucose measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam |
| Serum Uric Acid postprandial concentration | Baseline, 30, 60, 90 and 120 minutes | Serum Uric Acid measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam |
| Plasma Glutathione Peroxidase postprandial activity | Baseline, 30, 60, 90 and 120 minutes | Plasma Glutathione Peroxidase activity measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam |
| Postprandial Plasma Total Antioxidant Capacity | Baseline, 30, 60, 90 and 120 minutes | Plasma Total Antioxidant capacity measured at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam |
| Serum LDL-cholesterol postprandial concentration | Baseline, 30, 60, 90 and 120 minutes | Serum LDL-cholesterol calculated at baseline and each 30 minutes during 2 hours after consuming 60 g of the experimental jam |
Countries
Spain
Outcome results
None listed