Chronic Obstructive Pulmonary Disease COPD
Conditions
Keywords
COPD, Cognitive Dysfunction, Pulmonary Rehabilitation, Quality of life, Cognitive rehabilitation
Brief summary
The purpose of this project is to investigate whether a 12-week, fulltime pulmonary rehabilitation program can enhance cognitive functioning, mood, anxiety, and quality of life in patients with Chronic Obstructive Pulmonary Disease (COPD).
Interventions
OTHERExtensive Pulmonary Rehabilitation Program
Fulltime pulmonary rehabilitation program. Duration: 12 weeks
Sponsors
Revant Schoondonck Center for Pulmonary Rehabilitation Breda
Revant Innovation foundation
Fonds NutsOhra
Tilburg University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* COPD * Referral to the Extensive Pulmonary Rehabilitation Program
Exclusion criteria
* Unfinished primary school * Referral to the Compact Pulmonary Rehabilitation Program
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Subjective Cognitive Functioning | In the experimental group, this measure is assessed in the first and last week of rehabilitation with an average time frame of 11 weeks. In the Control group, this measure is assessed before and after waiting time with an average time frame of 5 weeks. | Cognitive Failures Questionnaire (CFQ) |
| Change in Mood and Anxiety | In the experimental group, this measure is assessed in the first and last week of rehabilitation with an average time frame of 11 weeks. In the Control group, this measure is assessed before and after waiting time with an average time frame of 5 weeks. | Hospital Anxiety and Depression Scale (HADS) Symptom Checklist 90 - Revised (SCL-90-R), subscales Anxiety, Depression, Agoraphobia |
| Change in Quality of Life | In the experimental group, this measure is assessed in the first and last week of rehabilitation with an average time frame of 11 weeks. In the Control group, this measure is assessed before and after waiting time with an average time frame of 5 weeks. | Saint George Respiratory Questionnaire (SGRQ) SF-36 Health Survey |
| Change in 6 Minute Walking distance Test(6-MWT) | In the experimental group, this measure is assessed in the first and last week of rehabilitation with an average time frame of 11 weeks. In the Control group, this measure is assessed before and after waiting time with an average time frame of 5 weeks. | 6 Minute Walking distance Test (6-MWT) |
| Change in Objective Cognitive functioning | In the experimental group, this measure is assessed in the first and last week of rehabilitation with an average time frame of 11 weeks. In the Control group, this measure is assessed before and after waiting time with an average time frame of 5 weeks. | CNS-Vital Signs, computerized neuropsychological assessment WMS - Verbal Paired Associates Direct Recall Word fluency-category (GIT): animals & profession Letter fluency: D-A-T Purdue Pegboard |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Fatigue | In the experimental group, this measure is assessed in the first and last week of rehabilitation with an average time frame of 11 weeks. In the Control group, this measure is assessed before and after waiting time with an average time frame of 5 weeks. | Chronic Respiratory Questionnaire (CRQ), subscale fatigue |
| Dropout from pulmonary rehabilitation | From the moment of randomization untill the moment of dropout from pulmonary rehabilitation, assessed up to 1 year after randomization. | Dropout can be specified as the percentage of patients who, though eligible, do not start pulmonary rehabilitation or patients who do not finish pulmonary rehabilitation. Dropout is further specified in the following categories: death, disease, motivation, practical (e.g. move). We use this measure to explore the predictors (e.g., age, education, cognitive functioning) of dropout from pulmonary rehabilitation. |
| Adherence to pulmonary rehabilitation | These data are collected during the total period of pulmonary rehabilitation, which has a time frame of 12 weeks. | Percentage of attendance of treatment session is collected from patients medical records. Adherence to pulmonary rehabilitation is specified as the percentage of the prescribed treatment sessions that patients actually attend. Adherence is further specified in the following categories: disease, motivation, other. We use this measure to explore the predictors (e.g., age, education, cognitive functioning) of adherence to pulmonary rehabilitation. |
Countries
Netherlands
Outcome results
None listed