Nutritional and Metabolic Diseases
Conditions
Brief summary
The purpose of this study is to investigate the appetite, insulin and incretin hormone responses to a high-calcium meal.
Detailed description
Participants will be provided with control and high-calcium meals. Insulin, appetite, glucagon-like peptide-1 and glucose-dependent insulinotropic peptide responses will be assessed, along with rates of substrate oxidation.
Interventions
DIETARY_SUPPLEMENTCalcium
Milk-calcium supplement
Sponsors
Northumbria University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
MALE
Healthy volunteers
Yes
Inclusion criteria
* recreationally active * male
Exclusion criteria
* food intolerances/allergies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Subjective appetite ratings | 3 hour | Subjective ratings of appetite assessed by visual analogue scales. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Serum insulin concentration | 2 hour | 2 hour area under the curve for serum insulin following breakfast consumption |
| Plasma glucose-dependent insulinotropic peptide concentration | 2 hour | 2 hour area under the curve for plasma glucose-dependent insulinotropic peptide following breakfast consumption |
| Plasma glucagon-like peptide-1 concentration | 2 hour | 2 hour area under the curve for plasma glucagon-like peptide-1 following breakfast consumption |
Other
| Measure | Time frame | Description |
|---|---|---|
| Total fat oxidised during 60 min of exercise (g) | 1 hour | Assessed by indirect calorimetry |
Countries
United Kingdom
Outcome results
None listed