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Calorie Anticipation and Food Intake

Differences in Physiological Responses of Satiety and Reward After (in)Consistent Calorie Cues.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01680315
Enrollment
12
Registered
2012-09-07
Start date
2012-05-31
Completion date
2012-08-31
Last updated
2012-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eating Behaviour, Obesity

Keywords

Satiety,, satiation,, anticipation,, food intake

Brief summary

The regulation of our food intake is on the short-term guided by appetite and satiety signals generated by the sight and consumption of food. Food intake is not only regulated by appetite and satiety signals - external cues also play an important role. It has been observed that food intake and the pleasure derived from consumption is affected by manipulation of the external cues. The investigators will assess the contribution of food anticipation (calorie information) and actual consumption of a test food (calorie intake) on in satiety responses (such as ghrelin responses, appetite and subsequent food intake). The investigators expect the information on the amount of calories, rather than the actual amount of calories in the food, to predict the ghrelin responses and the subsequent intake of a second meal.

Detailed description

In a randomized cross-over design with 4 conditions, all participants will consume twice the low-caloric food (once with the low-calorie information and once with the high-calorie information) and twice the high-caloric food (again, once with the low-calorie information and once with the high-calorie information) in a randomized order.

Interventions

BEHAVIORALlow calorie yogurt

all participants consumed twice the low-caloric food (once with the low-calorie information and once with the high-calorie information)

BEHAVIORALhigh calorie yogurt

all participants consumed twice the high-caloric food (once with the low-calorie information and once with the high-calorie information)

Sponsors

Uppsala University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* female * healthy * being used to eat breakfast regularly (≥ 5 times a week).

Exclusion criteria

* hypersensitivity for the ingredients of the foods under study; * lack of appetite; following an energy-restricted diet or change in body weight \> 5 kg; or * being a vegan or vegetarian. Participants reported not using products that are artificially sweetened, nor sugar in coffee and/or tea.

Design outcomes

Primary

MeasureTime frame
Food intake60 min (Ad libitum test meal after 1 hr)

Secondary

MeasureTime frame
Serum concentrations total ghrelin60 min (4 samples - every 20 min)

Other

MeasureTime frame
appetite ratings80 min (5 samples - every 20 min)
Serum cortisol concentrations60 min (4 samples - every 20 min)

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026