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Effect of 3 Years of Exercise on Development of Atrial Fibrillation

Effect of 3 Years of Exercise on Development of Atrial Fibrillation - A Generation 100 Substudy

Status
Active, not recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01680302
Enrollment
1567
Registered
2012-09-07
Start date
2012-09-30
Completion date
2026-06-30
Last updated
2022-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation

Keywords

Atrial fibrillation, Prevention, Exercise

Brief summary

This is a substudy of Generation 100. In that study, 4000 healthy persons between 70 and 75 will be randomised to a moderate intensity training group, a high intensity training group or control group, with 3 years of exercise. The investigators will follow these persons and register all who develop atrial fibrillation during these 3 years, and at follow-up after ended intervention to see if there is differences in the number of persons who develop atrial fibrillation in the 3 groups.

Interventions

BEHAVIORALHigh intensity exercise
BEHAVIORALControl

Advised to follow current guidelines for physical activity, but exercise on their own.

Sponsors

St. Olavs Hospital
CollaboratorOTHER
Norwegian University of Science and Technology
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
70 Years to 75 Years
Healthy volunteers
Yes

Inclusion criteria

* Participating in the Generation 100 study

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
Number of persons who develop atrial fibrillation during the 3 year intervention period3 yearsPeople who already have the diagnosis before randomisation will not be counted.

Secondary

MeasureTime frame
Number of persons who develop atrial fibrillation during the 6 years after randomisation6 years

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026