Macular Hole
Conditions
Keywords
Macular hole, Vitreoretinal surgery, Macular surgery, Air tamponade
Brief summary
Macular hole is a hole formation which takes place in the center of the retina. Such a hole needs surgical steps in order to close. Closure of the macular hole will lead to a substantially improvement of vision in most cases. Following macular hole surgery a tamponade of intraocular gas is normally injected in order to keep the macula dry for the postoperative period. Postoperative face down position for a week was earlier standard. Several authors report of good closure rates with both air tamponade or lack of face down positioning. In this study standard pars plana vitrectomy with peeling of the internal limiting membrane (ILM) will be performed. The gas tamponade will be replaced by air. Postoperative face down positioning will not be used.
Interventions
PROCEDUREPars plana vitrectomy and postoperative air tamponade
Pars plans vitrectomy, ILM peeling and air tamponade. No postoperative face down positioning. All patients need to be pseudophakic prior to intervention.
Sponsors
Haukeland University Hospital
Helse Stavanger HF
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Idiopathic stage 2 - 4 macular hole * Duration of symptoms ≤ 36 months * Informed consent
Exclusion criteria
* Previous vitreomacular surgery * Myopia ≥ 6 diopters * Ocular trauma * Disease affecting visual function
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Closure rate of macular hole | 1 month after enrollment |
Secondary
| Measure | Time frame |
|---|---|
| Closure rate in macular holes larger than 400 micrometer | 1 month after enrollment |
Other
| Measure | Time frame |
|---|---|
| Visual gain after 6 months of follow up | 6 months after enrollment |
Countries
Norway
Outcome results
None listed