Postoperative Nausea and Vomiting
Conditions
Keywords
PONV, thyroid, surgery, nausea and vomiting, postoperative
Brief summary
Wound Drains after Thyroid- and Parathyroid Surgery Impact on Postoperative Nausea and Vomiting (PONV)
Detailed description
Postoperative nausea and vomiting (PONV) is common after thyroid surgery. Many patients describe PONV as more irritant in the postoperative course than the endured pain. Postoperative drains are put after thyroid surgery to early recognize bleeding and to collect wound secretion to avoid pressure on the trachea. Whether wound drains do impact on PONV is not known. Therefore, we tested the impact of wound drains on PONV after thyroid- and parathyroid surgery in a randomized controlled clinical trial.
Interventions
DEVICEPlacement of a wound drain post surgery (Redon; Medicoplast)
The wound drain, type Redon Drainage 3.0 mm in diameter
OTHERNo-drain after surgery
After surgery, no drain was put
Sponsors
Kantonsspital Liestal
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 95 Years
Healthy volunteers
No
Inclusion criteria
* older than 18 years of age * informed consent * planed thyroid- or parathyroid resection * euthyreostatic preoperative condition
Exclusion criteria
* younger than 18 years of age * pregnancy * no informed consent * retrosternal struma * known postoperative nausea and vomiting prior to surgery * severe and life threatening systemic health issues
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of post-operative nausea using visual analogue scale (VAS) | 24 hours post surgery | The development of postoperative nausea was determined using a standard visual analogue scale (VAS) with range of 0 to 10. 0 indicated no nausea, 10 indicated very severe nausea. The patients indicated their felt degree of nausea a number between 0 to 10. |
| Assessment of postoperative vomiting using visual analogue scale (VAS) | 24 hours post surgery | The development of postoperative vomiting was determined using a standard Visual analogue scale (VAS) with range of 0 to 10. 0 indicated no nausea, 10 indicated very severe nausea. The patients indicated their felt degree of vomiting indicating a number between 0 to 10. The number of vomiting was counted within the first 48h post surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Antiemetic therapy post surgery in patients with and without postoperative drainage | after 48 hours | In the postoperative course, we counted the amount of anti-emetic interventions for patients post surgery over the first 48 hours. The givage of anti-emetic drugs was based on a prior determined protocol, that was strictly followed. The protocol was as follows for antiemetic drugs: First line Drug: Tropisetron 2 mg i.v. when patient is vomiting, max. twice a day. Second line therapy: Haloperidol 0.5 mg i.v. with a maximum of 3 mg every 24 hours, when first line therapy is not sufficient. The change to second line therapy is controlled by the study physician. |
Countries
Switzerland
Outcome results
None listed