Anesthesia, Local
Conditions
Keywords
Transversus abdominis plane block, Ultrasound guided nerve block
Brief summary
In this study we investigate the following properties of the transversus abdominis plane block in healthy volunteers: 1. Cutaneous analgesic distribution 2. Muscular affection 3. Reproducibility
Interventions
DRUGRopivacaine
Unilateral, single shot, ultrasound-guided, transversus abdominis plane block with 20 ml ropivacaine (7.5 mg/ml)
Sponsors
Hillerod Hospital, Denmark
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Capable * American society of anesthesiologists classification 1 or 2 * Written informed consent
Exclusion criteria
* Age below 18 years * American society of anesthesiologists classification above 2 * Body weight below 50 kg * Body mass index \> 35 kg/m2 * Previous abdominal surgery * Acute or chronic pain * Use of pain medication less than 24 h prior to study start * Allergy to local anesthetics * Pregnancy * Breastfeeding
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cutaneous analgesic distribution | 90 min | Cutaneous analgesic distribution 90 min after transversus abdominis plane block administration |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Muscular affection of the transversus abdominis plane block | 90 min | Abdominal wall muscle affection of the transversus abdominal plane block measured by ultrasonography under standardized conditions |
| Reproducibility of the transversus abdominis plane block | At least 2 days | Reproducibility of the transversus abdominis plane block with respect to: 1. Cutaneous analgesic distribution 2. Abdominal wall muscle affection measured in the same individual separated by at least 2 days |
Countries
Denmark
Outcome results
None listed