Embryo Kinetics
Conditions
Keywords
time-lapse, FSH, kinetics
Brief summary
Different kinetics markers have been proposed to select embryos with higher implantation rates. The effect of external factors on these markers, such as the stimulation protocol should be analyzed. There are two different types of FSH that are commonly used for in vitro fertilization (IVF) in egg donation cycles, recombinant FSH and human FSH. The effect of each kind of hormone on embryo kinetcis is still unknown. The aim of this study is to observe if there is a difference in embryo kinetics and morphology as well as oocyte morphological parameters between the two types of FSH and therefore to analyze if such markers can be used despite of the stimulation protocols chosen.
Interventions
PROCEDUREStimulation with human FSH
Human FSH
PROCEDUREStimulation with recombinant FSH
Recombinant FSH
Sponsors
IVI Madrid
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
•Egg donation cycles with more than 8MII in oocyte retrieval day
Exclusion criteria
* Male factor * Uterine malformations * genetic alterations
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| time of cell cleavage | February 2012 | Analysis of cell cleavage |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Embryo and oocyte morphology | February 2012 | Analysis of all oocytes |
| Outcome rates (implantation, pregnancy and miscarriage rate) | February 2012 | Time requierd to know all the implantation, pregnancy and miscarriage rate |
Countries
Spain
Outcome results
None listed