Heart; Disease,Complicating Pregnancy, Pre-existing
Conditions
Keywords
induction of labour, heart disease patients
Brief summary
Fifty pregnant patients with acquired and congenital heart disease between 38-41 weeks were randomised into elective induction and spontaneous labour groups only after bishop score was equal to or more than 6.It was concluded that induction of labour with oxytocin is a relatively safe procedure in women with low risk heart disease with NYHA class I and II. It resulted in a similar caesarean delivery rate and was not associated with more maternal and neonatal complications.
Detailed description
Induction of labour was done with oxytocin. An infusion of 30U oxytocin diluted in 500ml normal saline was prepared and given through infusion pump at initial rate of 3mU/min. Subsequently dose was increased 3mU/min every 45 min till adequate uterine contractions were established. Epidural analgesia was provided wherever feasible or Injection Morphine 2-5mg was given intravenously for pain relief.
Interventions
DRUGOxytocin
Arm - Induction of labour
Sponsors
Post Graduate Institute of Medical Education and Research, Chandigarh
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
19 Years to 37 Years
Healthy volunteers
No
Inclusion criteria
* NYHA class I-II * cephalic presentation * singleton gestation
Exclusion criteria
* previous cesarean section, * Primary pulmonary hypertension, * Eisenmenger syndrome, * Marfan syndrome, * Left heart obstruction, * Prior cardiac event or arrhythmia, * Malformed fetus, * Severe anemia (\<7g/dl), * Intrauterine fetal death, * other obstetrical indications for induction of labour * patients on anticoagulation.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Duration of labour | at the time of delivery | — |
| Rate of caesarean section | at the time of delivery | mode of delivery and rate of caesarean section with indication |
| Number of patients with delivery during workday hours | at the time of delivery | — |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| number of patients with adverse neonatal outcome | day 5 | apgar score number of admissions to neonatal intensive care unit number of neonatal deaths |
| number of patients with maternal complications | day 5 | maternal complications include postpartum hemorrhage, infection, cardiac complications and number of maternal deaths |
Countries
India
Outcome results
None listed