Ovarian Stimulation and Intrauterine Insemination in Women With Polycystic Ovarian Syndrome

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01675843

Acronym

OSIPS

Enrollment

140

Registered

2012-08-30

Start date

2010-05-31

Completion date

Unknown

Last updated

2012-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility, Intrauterine Insemination, Polycystic Ovarian Syndrome

Keywords

Infertility, PCOS, IUI

Brief summary

The study null hypothethesis is: intrauterine insemination (IUI) does not improve pregnancy rates in women with polycystic ovary syndrome. Infertile women with pcos will receive gonadotropins for ovarian stimulation and then randomize to either IUI or timed intercourse (TI)

Interventions

PROCEDUREIntrauterine insemination (IUI)

The male semen is obtained then processed by swim up technique and then introduced into the uterus by special catheter.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

21 Years to 38 Years

Healthy volunteers

Inclusion criteria

\- women who failed to get pregnant after 6 ovulation induction cycles with clomiphene citrate (cc) alone, despite of being ovulating with cc, having patent Fallopian tubes as confirmed by hysterosalpingography and their partners had fertile semen parameters according to criteria of World Health Organization (WHO 2010)

Exclusion criteria

male factor infertility

Design outcomes

Primary

Measure	Time frame
Live Birth Rate	20 months

Secondary

Measure	Time frame
Clinical pregnancy rate	16 months

Other

Measure	Time frame
multiple pregnancy rate	20 months

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026