Myofascial Trigger Points
Conditions
Keywords
Myofascial pain, Trigger point, Nitroglycerin
Brief summary
The purpose of this study is to determine whether a topical nitroglycerine patch applied daily over a trapezius trigger point can improve patients' symptoms. If there is improvement, this open label study will help determine the degree of improvement and contribute to the design of a larger double blind placebo controlled trial. We would consider moving forward to a large randomized trial if: * The intervention is acceptable to patients (\>= 70%) and * Compliance is satisfactory (\>=80%) and * We find preliminary evidence of efficacy, i.e. average reduction in pain of 20mm on the VAS.
Interventions
Nitroglycerin 0.1 mg/hr patch
Sponsors
Study design
Eligibility
Inclusion criteria
* Inclusion criteria include age between 19 and 65 years old, myofascial pain lasting at least 6 months, and a myofascial trigger point point in the trapezius muscle.
Exclusion criteria
* Our
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain at the time of clinic visit and over the previous week as measured by a Visual Analog Scale, VAS, for pain and a pressure algometer measurement to obtain pressure pain thresholds over the patients trigger point. | 1 month |
Secondary
| Measure | Time frame |
|---|---|
| As another secondary outcome we will ask the participants whether the benefits of the treatment are good enough that they would continue using the nitroglycerin patch. This will be a yes or no response. | 1 month |