Gastric Cancer, Colorectal Cancer and Pre-cancer Polyps, Pancreatic Cancer
Conditions
Brief summary
Colorectal cancers account for 783,000 new cases and cause 437,000 deaths per year across the world. Diagnosis in the early stages improves survival rates. Up to now, these cancers are mostly diagnosed only at later stages of the disease's course through histoimmune staining and molecular biology processes on the tissues biopsied from the gastrointestinal system under invasive diagnostic procedures of colonoscopy. Oral fluid presents a large protein complexity and has been recently used as a diagnostic biofluid for oral, as well as systematic diseases. Using oral fluid as a bio-marker for the colorectal cancer can be advantageous as it contains gastrointestinal fluids, in addition to bacteria and bacteria lysate, which can also serve as a bio-markers' source for colorectal cancers. Proteomic technologies provide the tools needed to discover and identify disease-associated biomarkers. The aim of the present study is to identify salivary bio-markers in patients suffering from colorectal cancers.
Interventions
OTHERSalivary samples
Each participant will give a sample of saliva through spitting for 10 minutes in a sterile tube.
Sponsors
Hadassah Medical Organization
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Has not yet started treatment for the identified cancer
Exclusion criteria
* medically compromised patients * congenital syndromes * being treated with radiotherapy or chemotherapy.
Countries
Israel
Outcome results
None listed