Chronic Obstructive Pulmonary Disease
Conditions
Keywords
COPD, IPV
Brief summary
In this study the invetigators seek an answer on the following hypothesis: * What are the long term effects of an IPV treatment evaluated with classical outcome parameters? (FEV1, Raw) * Is the possible effect noticeable on the novel technique and is this comparable with the classical outcome parameters?
Detailed description
A Multicenter study conducted in university Hospital Antwerp (UZA) and ZNA Middelheim. Tests are taken before and after one week IPV treatment. IPV is applied for 1 week during the physical therapy treatment of chronic obstructive pulmonary desease (COPD) patients admitted to the hospital for an excarebation. The IPV treatment is an additional treatment upon the standard treatment of the patients. The standard treatment consists out of existing drainage techniques to remove secretion out of the lungs by means of breathing control exercises. Patients are randomized into either the experimental group or the control group. The control group receives a standard physical therapy treatment without additional IPV treatment.
Interventions
OTHERstandard treatment
breathing control exercises
Sponsors
Artesis University College, Antwerp
FLUIDDA nv
University Hospital, Antwerp
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
30 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients admitted in the hospital for a acute exacerbation * Mild to severe COPD
Exclusion criteria
* Ischemic / ventricular aritmic * Tracheotomise * Pneumothorax * Facial deformity * Recent nose, mouth or ear operations * Recent gastric operations. * Intubated * Epilepsy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Lung function testing | baseline and after one week | (spirometric , bodybox en diffusion) Performed in the lung function laboratory according to ERS standards using Jaeger 5.1 device vital capacity (VC), FEV1, FEV1/VC, peak expiratory flow (PEF), MMEF 75/25, MEF 50, MEF 25, MIF 50, RV, total lung capacity (TLC), functionale residual capacity (FRC), resistance, spec resistance, TCO, alveolar volume (VA), TCO/VA, Maximal inspiratory pressure, Maximal expiratory pressure |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| functional respiratory imaging | at baseline and after one week | A 3D CT-scan is take. Images are uploaded into a software program for post processing 3D images are made and images are post processed |
Other
| Measure | Time frame | Description |
|---|---|---|
| questionnaires | 1 week | St george Borg MRC |
Countries
Belgium
Contacts
Primary ContactKris Ides, Msc
Outcome results
None listed