Evaluation of the Lung Recruitment and End-expiratory Lung Collapse in Acute Respiratory Distress Syndrome (ARDS)

Evaluation of the Lung Recruitment and End-expiratory Lung Collapse in Patients With Acute Respiratory Distress Syndrome

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01670747

Enrollment

Registered

2012-08-22

Start date

2012-09-30

Completion date

2015-03-31

Last updated

2015-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ARDS: Acute Respiratory Distress Syndrome

Brief summary

In this study gas-exchange and respiratory mechanics variations to PEEP change will be correlated to CT lung morphological modifications assessed at different airway pressures (5, 15, 30 and 45 cmH2O).

Interventions

RADIATIONChest computed tomography

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Clinical diagnosis of acute lung injury/ acute respiratory distress syndrome * Mechanical ventilation

Exclusion criteria

* Clinical diagnosis of chronic obstructive pulmonary disease * Clinical diagnosis of pneumothorax * Haemodynamic instability

Design outcomes

Primary

Measure	Time frame	Description
Computer Tomography (CT) scan lung recruitment and CT lung weight	Study day (day 1)	Aim of the study is to determine the relationship between the opening pressures (recruitment) and closing pressures (PEEP) in order to prevent the opening and closing of the lung parenchyma

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 10, 2026