PECBLOCK for the Treatment of Pain After Breast Surgery

The Pectoral Nerve Block (PECBLOCK) for the Treatment of Pain After Breast Cancer Surgery.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01670448

Acronym

PECBLOC

Enrollment

128

Registered

2012-08-22

Start date

2014-01-31

Completion date

2015-06-30

Last updated

2019-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer, Pain

Keywords

Postoperative pain, Chronic pain prevention, Regional anesthesia, Mastectomy

Brief summary

Pain after breast cancer surgery could be severe and about 1/3 of patients will develop chronic pain. The PECBLOCK is the injection of local anesthetics between the two pectoral muscles to block pectoral nerves and intercostal nerves innervating the breast. The aim of this study is to evaluate the efficacy of the PECBLOCK performed under echoguidance in minor and major breast surgery. The prevention of chronic pain following surgery will also be evaluated.

Interventions

PROCEDUREPECBLOCK under echoguidance

Performance of block under echography

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

* women aged 18-85 yrs old * patients ASA status I-IV

Exclusion criteria

* refusal of the PECBLOCK * allergy to a drug used in the protocol (local anesthetic) * patients with chronic pain before the surgery

Design outcomes

Primary

Measure	Time frame	Description
Pain score at rest in the recovery room	30 min after entering the recovery room or just before morphine administration if needed	Using a 0-10 verbal numerical scale where 0 is no pain and 10 the worst pain imaginable

Secondary

Measure	Time frame	Description
Total morphine consumption in the recovery room	in the recovery room before discharge (after 1 h on average))	When surgery is over and the patient is brought to the recovery room, the total morphine consumption in mg used in the recovery (for pain less than 4/10) is recorded

Other

Measure	Time frame	Description
Total sufentanil consumption during surgery	at the end of surgery (1-2 h on average)	When surgery is over, 1-2 h on average depending if it is a tumorectomy or a mastectomy, the total sufentanil consumption in micrograms during surgery is recorded.
Assess any complication from PECBLOCK	first 24 hours post surgery	Cardiovascular collapse, anaphylactic shock, hematoma, bleeding..?

Countries

Canada, France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 24, 2026