Cardiac Arrest, Sepsis
Conditions
Keywords
Cardiac Arrest, Sepsis, Biological Markers, Anti-Inflammation Agents, Antioxidants
Brief summary
The objective of this study is to find a new therapeutic strategy by investigating the serial serum samples of patients with sepsis or postresuscitation state.
Interventions
None listed
Sponsors
Seoul National University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age over 16 years old * Admitted to ICU * Diagnosed as having sepsis or as postresuscitation status * Definition of sepsis: 2 or more SIRS criteria + infection is suspected * Definition of postresuscitation status: Survived from non-traumatic cardiac arrest
Exclusion criteria
* refusal to participate * DNAR status
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 1-month mortality | 1 month | All cause mortality within 1-month |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hospital mortality | until hospital discharge, an expected average of 2 weeks | All cause mortality during hospitalization |
| ICU length of stay | Until ward transfer or discharge, an expected average of 7 days | — |
| Favorable neurologic outcome | at discharge, an expected average of 2 weeks and at 6-month | Favorable neurologic outcome is used for outcome measure in postresuscitation patients only. Favorable neurologic outcome means cerebral performance category 1 and 2. This outcome is measured at discharge and 6-month after admission. |
Countries
South Korea
Contacts
Primary ContactKyung Su Kim, MD, PhD
Outcome results
None listed