Turner Syndrome Prenatal Diagnosis Study

National Collaborative Study of Girls Prenatally Diagnosed With Turner Syndrome Karyotypes

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01668251

Enrollment

Registered

2012-08-20

Start date

2006-01-31

Completion date

2017-01-31

Last updated

2012-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Turner Syndrome

Keywords

Turner syndrome, Diagnosis, prenatal

Brief summary

The goal of this study is to compare the features of Turner syndrome in girls who are diagnosed before birth because of fetal concerns versus those who are diagnosed when their mother has an amniocentesis for another reason.

Detailed description

This is an observational study which will look at girls who are diagnosed with Turner syndrome before they are born. Girls will be divided into two groups: 1) those diagnosed because of features seen on ultrasound which raised the question of Turner syndrome and 2) those diagnosed incidentally when their mother had an amniocentesis for another reason such as advanced maternal age. No clinical procedures nor interventions will be done as part of this data collection study which will occur for the first 3 to 6 years of the girl's life. The investigators will be looking to see if girls who are diagnosed incidentally have less features of Turner syndrome than those girls who are diagnosed because of fetal ultrasound.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

No minimum to 3 Months

Healthy volunteers

Inclusion criteria

* Turner syndrome diagnosed prenatally * Less than 4 months of age at time of enrollment

Exclusion criteria

* Turner syndrome diagnosed postnatally * Older than 4 months of age at time of enrollment

Design outcomes

Primary

Measure	Time frame	Description
Number of signs of Turner syndrome	three to six years	Girls diagnosed with Turner syndrome by fetal ascertainment will have more signs of Turner syndrome than girls diagnosed by maternal ascertainment

Secondary

Measure	Time frame	Description
Growth	three to six years	Do girls with Turner syndrome ascertained by fetal ascertainment grow differently than girls ascertained by maternal ascertainment.

Countries

United States

Contacts

Primary ContactPatricia Fechner, MD

patricia.fechner@seattlechildrens.org206-987-5037

Outcome results