Infertility
Conditions
Brief summary
Perifollicular Doppler could reflect the quality of the follicle's vascularization and, consequently, the one of the oocyte that ensues from it. Perifollicuar Doppler is the analysis, in ultrasound, of the blood flow in vessels surrounding the follicle. The goal of this study is to evaluate if there is a link, in natural cycle In Vitro Fertilization, between the quality of the vascularization and the one of the oocyte, the embryo and the pregnancy.
Interventions
PROCEDUREDoppler ultrasound
Doppler Ultrasound
Sponsors
Clinique Ovo
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 38 Years
Healthy volunteers
No
Inclusion criteria
* Patient with a natural In Vitro Fertilization cycle. * Patient under 38 years old * Body mass indice under 35 * Ovulatory cycles between 20-35 days
Exclusion criteria
* Patient with a stimulation In Vitro Fertilization cycle * Patient with a naturalIn Vitro Fertilization cycle with egg donor * Patient with a natural In Vitro Fertilization cycle with freezing embryo * Smoking patient * Diabetic patient * Patient with treatment of antihypertensive drug, anticoagulant, antiplatelet, vasodilator * Body mass indice over 35 * Patient over 38 years old * Patient without ovulation or cycle over 35 days * Percutaneous Epididymal Sperm Aspiration (PESA), Testicular Sperm Extraction (TESE) or micro TESE
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Quality perifollicular doppler and quality of the oocyte | 2 weeks | The measurements are done twice; on days of induction and oocyte retrieval. During the blood sample collection on the day of the induction, there is also a measurement of progesterone, estradiol and luteinizing hormone (LH). |
Countries
Canada
Outcome results
None listed