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Diagnosis and Treatment of Minor Ischaemic Stroke According to the Etiology and Pathogenesis

Diagnosis and Treatment of Minor Ischaemic Stroke According to the Etiology and Pathogenesis

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01665729
Enrollment
1000
Registered
2012-08-15
Start date
2011-06-30
Completion date
2015-12-31
Last updated
2012-08-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischaemic Stroke

Keywords

etiology, pathogenesis, minor ischaemic stroke, types, intervention

Brief summary

Negligence or contempt of the etiology and pathogenesis of minor ischaemic stroke in the early diagnosis and effective treatment leads to more than 40-50% of patient with recurrent episodes, and 10% patient died. Therefore, diagnosis and treatment of minor ischaemic stroke according to the etiology and pathogenesis is important. The 2007 Korean modified TOAST type got some progress, but there exists two major disadvantages: imperfect diagnosis and pathogenesis of perforator artery infarction etiology; lack of typing according to the pathogenesis of large atherosclerotic infarction and taking measures of treatment according to the new types. Recently, domestic professor Gaoshan proposes new approach to diagnose and treat minor ischaemic stroke according to the etiology and pathogenesis of CISS typing, but the pathogenesis of hypoperfusion infarction with severe stenosis of large artery is unclear. Is it low perfusion? Or artery-artery embolization? Or both? How to distinguish the pathogenesis of branch artery disease: by atherosclerosis? Or hyalinosis? Or both? How to check the validity of clinical types? This study take different interventions according to different types and observation of the long term clinical results of intervention( mortality, recurrence rate, disability rate and rate of cerebral hemorrhage and subarachnoid hemorrhage), in order to clarify the new types can indeed solve the current problem of minor ischaemic stroke with high mortality, recurrence rate, disability rate and rate of cerebral hemorrhage and subarachnoid hemorrhage.

Interventions

None listed

Sponsors

Li Haiyan
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to 79 Years
Healthy volunteers
No

Inclusion criteria

one of two conditions: 1. conscious patients with any of NIHSS score = 1,or 2. NIHSS ≤ 3

Exclusion criteria

* patients Over 80 years of age * patients With serious heart, lung, liver, kidney dysfunction or * severe systemic complications, * a known tumor, * pregnancy, * having a history of cerebral hemorrhage

Countries

China

Contacts

Primary ContactZhengqi Lu, prof.
lzq1828@yahoo.com.cn86 13570102668
Backup ContactHaiyan Li, Dr.
lihaiyan162@yahoo.com.cn86 15920474159

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026