The Clinical and Subjective Performance of Three Different MPDS With Silicon Hydrogel Lenses

The Evaluation of the Clinical and Subjective Performance of Three Different Contact Lens Care Solutions With Silicon Hydrogel Lenses

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01665612

Enrollment

Registered

2012-08-15

Start date

2012-08-31

Completion date

Unknown

Last updated

2015-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adverse Reaction to Contact Lens Solution

Keywords

Contact lens, Care solution, MPDS, comfort

Brief summary

The purpose of the clinical investigation is to assess the clinical and subjective performance of three novel multipurpose disinfecting solutions (MPDS) in daily wear with two silicone hydrogel contact lenses (Lotrafilcon B and Comfilcon A).

Interventions

DEVICEContact lens care solution

Comparison of clinical and subjective performation of the contact lens care solutions used with two types of contact lenses

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* age above 18 * experienced contact lens user * good health (self-reported)

Exclusion criteria

* eye disease or eye operations * pregnancy * medication that can affect sight

Design outcomes

Primary

Measure	Time frame	Description
Clinical performance	1 month	TBUT, conjunctival and limbal hyperemia, corneal vascularization, epithelial and stromal oedema, corneal infiltrates, endothelial regularity, corneal staining and papillar conjunctivitis

Secondary

Measure	Time frame	Description
Subjective performance	1 month	E.g. Comfort

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026