Major Depressive Disorder (MDD)

Effectiveness of Physicians' Education, Implementation and Follow up of Current Recommendations Regarding Screening for Major Depressive Disorder in High Risk Patients on Improving the Under-Recognition Rates of Depression in Primary Care

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01662817

Enrollment

525

Registered

2012-08-10

Start date

2009-09-30

Completion date

2010-07-31

Last updated

2012-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Brief summary

The purpose of this study is to assess the effectiveness of systematic screening for depression in high-risk patient participants in everyday clinical practice. Systematic screening for depression in high-risk patients is recommended to be included as a usual practice but its effectiveness in this context remains controversial. In this study, 35 primary care physicians (PCPs) in Spain were assigned to intervention (receive one day training in depression screening guidelines and use guidelines for six months) and 34 PCPs were assigned to a control group (manage depression in the usual way for six months). There were a total of 525 patient participants with MDD.

Interventions

BEHAVIORALIntervention

PCP receives one day training in depression screening guidelines and uses guidelines for six months

BEHAVIORALControl

PCP manages depression in the usual way for six months

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* PCP Participants: PCPs informed of the study design and who agreed to be randomized to the intervention or control group * Patient Participants: Aged 18 years or older who provide a written consent for the collection and use of their clinical data

Exclusion criteria

* PCP Participants: If they already follow the recommendations on screening or were planning to do so. If they will be absent from their practice for a significant period during the study, or if they do not usually manage depression * PCP Participants: Those who were not able to understand the aims of the study

Design outcomes

Primary

Measure	Time frame
Percentage of Patient Participants with Under-Recognized Major Depressive Disorder (MDD) Episodes at 24 Weeks	24 Weeks

Secondary

Measure	Time frame
Change from Baseline in Primary Care Physician (PCP) Adherence to Intervention Questionnaire at 24 Weeks	Baseline, 24 Weeks
Change from Baseline in PCP Feasibility of Intervention Questionnaire at 24 Weeks	Baseline, 24 Weeks
Change from Baseline in PCP Acceptance of Intervention Questionnaire at 24 Weeks	Baseline, 24 Weeks
Mean Duration of Depressive Episodes in Patient Participants	24 Weeks
Percentage of Patient Participants with Under-Treatment of MDD Episodes at 24 Weeks	24 Weeks
Sheehan Disability Scale (SDS) Score in Patient Participants	24 Weeks
Mean Duration of Sick Leave Due to Depression in Patient Participants	24 Weeks
Percentage of Patient Participants with Sick Leave Due to Depression	24 Weeks
Clinical Global Impressions: Severity (CGI-S) Score in Patient Participants	24 Weeks

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 24, 2026