The Efficacy in Treatment of Female Pattern Hair Loss Using 5% Minoxidil Solution Combinded With Zinc Supplement

A Pilot Study of the Efficacy in Treatment of Female Pattern Hair Loss Using 5% Minoxidil Solution Combinded With Oral Chelated Zinc Supplement

Status

UNKNOWN

Phases

Phase 1Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01662089

Enrollment

Registered

2012-08-10

Start date

2012-01-31

Completion date

2012-12-31

Last updated

2012-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female Pattern Alopecia

Keywords

Female pattern hair loss

Brief summary

Zinc supplement is a popular trace element gave to Female pattern hair loss (FPHL) patient. But the type of patient, efficacy, and side effect in detail of zinc supplement are not well characterized. The purpose of this study is to determine efficacy and side effect of chelated zinc in FPHL who using 5%minoxidil solution.

Detailed description

5%minoxidil solution is standard treatment for Female pattern hair loss (FPHL) patient. We gave 15mg chelate Zinc / Placebo drug to patient as an additional trace element. Then measure growth of hair by Global photograph, Microscope hair count, micrometer and record case and side effect during 10 months of treatment.

Interventions

DRUG15 mg Chelate zinc supplement

15 mg Chelate zinc additional to standard 5% minoxidil

DRUGPlacebo drug supplement

Placebo drug instead of Zinc supplement

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Female Pattern Hair Loss ( Ludwig classification grade 1 and 2 )

Exclusion criteria

* Underlying disease ; Anemia, Diabetes, chronic alcoholism, previous gastrointestinal surgery, short bowel syndrome, Crohn's disease, digestive disorder, hypo/hyperthyroidism, sickle cell disease, autoimmune disease, iron deficiency * Psychologic disorder trichotillomania * Diet control * Pregnancy or lactation * On supplement diet within 3 month prior to trial

Design outcomes

Primary

Measure	Time frame	Description
Compare clinical improvement before and after treatment	6 month	Measure clinical by Global photographic view using 7 point scale. Review picture by 2 dermatologist
Compare hair density before and after treatmen	6 month	Measure Hair density by microscope photo of area 1 cm2. Conut number of hair in photo.
Compare average hair shaft diameter before and after treatment	6 month	Compare average hair shaft diameter before and after treatment Measure hair shaft diameter using electronic outside micrometer.

Secondary

Measure	Time frame	Description
Number of pateint with Side effect	6 month	Using side effect record form to record side effect from treatment Count number of pateint with side effect.

Countries

Thailand

Contacts

Primary ContactRattapon Thuangtong, MD

rattapongthuangtong@yahoo.com+662 419-7000

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026