Sleep Apnea, Obstructive
Conditions
Keywords
Obstructive Sleep Apnea
Brief summary
The purpose of this study is to check blood and urine levels to further define markers/tests in the blood and urine that would be useful in following patients with obstructive sleep apnea and then to see if by wearing CPAP every night, these markers can be reduced. This research is being done because currently there are no effective blood or urine markers to determine how well CPAP is working.
Detailed description
The goal of this study is to further define biomarkers that would be useful in following patients with obstructive sleep apnea and examining their response to compliance to therapy with CPAP. To date no correlation between biomarkers of oxidative stress and compliance to CPAP has been measured. CPAP is the most effective treatment for obstructive sleep apnea and has been show to reduce blood pressure and decrease oxidative stress.
Interventions
None listed
Sponsors
Georgetown University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Men and Women over 18 years suspected of having sleep apnea
Exclusion criteria
* Those under 18 years or not suspected of having sleep apnea
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Determining biomarkers for polysomnography characteristics before and after CPAP treatment | 6 months | The primary objective of this pilot study will determine the biomarkers for polysomnography characteristics with CPAP treatment from baseline to 6 months in patients with obstructive sleep apnea. The results will guide biomarker selection for full scale studies. |
Countries
United States
Outcome results
None listed