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The Association Between Arterial Stiffness and Assessment of Hydration State in Peritoneal Dialysis Patients

Volume Status in Peritoneal Dialysis Patients With Using Different Determining Methods.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01659333
Enrollment
60
Registered
2012-08-07
Start date
2011-01-31
Completion date
2012-02-29
Last updated
2012-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disorders Associated With Peritoneal Dialysis

Keywords

Peritoneal, Dialysis

Brief summary

Dry weight (DW) assessment is essential for the efficient treatment of peritoneal dialysis (PD) patients but so far objective methods for DW assessment have not been established for daily clinical practice. Our aim was to evaluate hydration state in PD patients by using a body composition monitor (BCM) and calf bioimpedance (c-BI) and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) levels and to compare both methods with arterial stiffness.

Detailed description

We evaluated 60 patients using a new BCM device that implies a validated body composition model. This method allows correct quantification of extracellular fluid overload or deficiency (normal limits:-1.1 to +1.1L). Patients were assigned to normo and hypervolemic groups according to BCM results. Also, normalized calf resistivity (nRho) was calculated from resistance at 5 Khz using c-BI and the levels of NT-proBNP were measured in all study patients. The analyses of arterial stiffness were performed by using the pulse wave velocity (PWV) technique on the patients. All patients underwent conventional echocardiography and their left ventricular diastolic functions were evaluated.

Interventions

None listed

Sponsors

TC Erciyes University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Peritoneal dialysis patients * All participants over 18 years of age

Exclusion criteria

* Patients with valvular heart disease * Patients with coronary artery disease * Patients with cardiomyopathy * Patients with ESRD who underwent hemodialysis

Design outcomes

Primary

MeasureTime frame
Terminated of patients recruitingOne year

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026