Skip to content

Adaptive Treatment for Adolescent Cannabis Use Disorders

Adaptive Treatment for Adolescent Cannabis Use Disorders

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01656707
Enrollment
172
Registered
2012-08-03
Start date
2011-09-30
Completion date
2016-07-31
Last updated
2017-04-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Addictive Behaviors, Cannabis Use Disorder, Mental Disorders

Keywords

Adolescents, Substance Use Disorders

Brief summary

The purpose of this study is to examine an Adaptive Treatment approach in order to improve outcomes of youth with Cannabis Use Disorders who are poor responders to treatment.

Detailed description

The study will address the current contrasts in youth response to treatment, the problem of poor response to treatment and the prevention of relapse. Results from the study may support Adaptive Treatment as an efficacious approach for youth with Cannabis Use Disorder who are poor responders to treatment. Poor responders fall into two categories, those who failed to achieve a negative drug urinalysis during the last session of the initial MET/CBT-7 treatment they attended, and those who either dropped out or were administratively discharged at any time during the initial MET/CBT-7 treatment.

Interventions

BEHAVIORALACRA

Ten weekly,60-minute therapy sessions including six individual, two parent/guardian and two joint (individual and parent/guardian).

BEHAVIORALCBT

10 weekly, 60-minute sessions of augmented individualized CBT

Sponsors

National Institute on Drug Abuse (NIDA)
CollaboratorNIH
UConn Health
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
13 Years to 18 Years
Healthy volunteers
No

Inclusion criteria

* 13-18 years of age at the time of intake assessment * Current diagnosis of DSM-IV Cannabis Abuse or Dependence * Able to read and comprehend English at a 5th grade level * Residence within 45 minutes drive from the UCHC Farmington treatment site * Participant and a parent/legal guardian responsible for providing collateral information agree to sign an IRB approved consent form * Participant and a parent/legal guardian responsible for providing collateral information agree to provide locator information * The family is not planning to move from the area during the next six months

Exclusion criteria

* Meet criteria for dependence of any other substance of abuse other than nicotine or alcohol * Report suicidal ideation with a plan, suicidal behavior, a plan to hurt oneself or other, or a history of self-injurious behavior all occurring in the last 30 days * Meet a lifetime diagnosis of schizophrenia * Has any current health (i.e. medical, psychiatric) condition that will compromise the participant's ability to regularly attend treatment * Demonstrate an inability or unwillingness to provide locator information

Design outcomes

Primary

MeasureTime frameDescription
1.) To evaluate the efficacy of AT for youth who have been defined as poor responders to an evidence-based practice intervention such as the initial MET/CBT-7.one yearEach participant will serve as his/her own control. The outcomes will include the T-ASI, T-ASI-P, and drug urinalyses.

Secondary

MeasureTime frameDescription
To assess outcomes as a function of mediator variables such as self-efficacy, coping skills, readiness to change, and environmental support (i.e., family and peer), within each of the AT interventions.one yearThe secondary outcome measures will include the SCQ, CRI, PRQ, and SSQ.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026