Effect of AXOS on the Colon Metabolism in Healthy Volunteers

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01656499

Enrollment

Registered

2012-08-03

Start date

2011-03-31

Completion date

2012-09-30

Last updated

2015-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gut Health

Brief summary

The purpose of this study is to evaluate the effect of AXOS on parameters of colon metabolism and gut health

Interventions

DIETARY_SUPPLEMENTArabinoxylanoligosaccharides

DIETARY_SUPPLEMENTMaltodextrine

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

BASIC_SCIENCE

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy volunteers * regular dietary pattern (3 meals/day) * age: 18-45y * BMI: 18,5-27 kg/m2

Exclusion criteria

* intake of antibiotics 1 month prior to the study * abdominal surgery in the past, with the exception of appendectomy * intake of medication influencing the gastro-intestinal system 14 days prior to the study * in treatment at a dietician * serious liver- or kidney failure * vegetarians * intake of pre- and/or probiotics * Exposure to radioactivity 1 year prior to the study

Design outcomes

Primary

Measure	Time frame
Fecal water toxicity	Participants are followed for 10 weeks, with measurements on 4 specific time points

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026