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Split Wound Comparison of Trichophytic Closure Techniques for Donor Site in Hair Transplantation

Split Wound Comparison of Trichophytic Closure Techniques for Donor Site in Hair Transplantation

Status
UNKNOWN
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01655602
Enrollment
10
Registered
2012-08-02
Start date
2012-07-31
Completion date
2013-05-31
Last updated
2012-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Androgenetic Alopecia

Keywords

Trichophytic closure, hair transplantation, donor site, Androgenetic alopecia

Brief summary

This study aim to compare cosmetic results between 3 trichophytic closure techniques for donor site (the trimming of upper, lower and both edge of linear incision) in hair transplantation.

Detailed description

Strip harvesting technique, a conventional hair transplantation procedure, is widely used in the treatment of androgenetic alopecia for more than half a century. It provides less time-consuming, more feasible and more cost-effective comparing with follicular unit extraction (FUE) technique. However, linear scar at the donor site is also introduced. The latest method to fine the scar at the donor site was invented and known as 'Trichophytic closure technique'. It can be done by trimming upper or lower wound edge for about 1 millimeter (as Fig.1) before wound closure. Then the linear scar will be less visible after hair growth. Anyway, there is no exactly wound edge (upper, lower or both) that recommended for the excellent cosmetic results without any severe side effects. Therefore, this study was designed to determine which is the best trichophytic closure technique. This research is a pilot, split-wound comparison study of trichophytic closure techniques for donor site in hair transplantation.10 males, aged ≥ 25 years, who require strip harvesting follicular unit transplantation in the treatment of androgenetic alopecia will be enrolled. Preoperative and perioperative process will be conducted as standard procedure except wound closure technique. Each incision wound of donor site will be equally divided into 3 parts (marked with tattoos as Fig.2) and each part will be randomly treated with different trichophytic closure techniques as below. * The 1-millimetre trimming of upper edge of linear incision before wound closure * The 1-millimetre trimming of lower edge of linear incision before wound closure * The 0.5-millimetre trimming of both edge of linear incision before wound closure For evaluation, we have planned to assess both cosmetic results and side effects as shown in the table. ( Table 1 - image file ) After data collecting process, we have planned to analyze the demographic data, rate of infection and other side effects in a descriptive manner. However, the evaluation for cosmetic results will be analyzed by paired t-test in the same technique at different follow up period and by one-way ANOVA between each technique at the same follow up period.

Interventions

PROCEDURETrichophytic closure upper edge trimming

'Trichophytic closure technique' can be done by trimming upper or lower wound edge for about 1 millimeter (as Fig.1) before wound closure. Then the linear scar will be less visible after hair growth. Anyway, there is no exactly wound edge (upper, lower or both) that recommended for the excellent cosmetic results without any severe side effects. Therefore, this study was designed to determine which is the best trichophytic closure technique.

PROCEDURETrichophytic closure lower edge trimming

'Trichophytic closure technique' can be done by trimming upper or lower wound edge for about 1 millimeter (as Fig.1) before wound closure. Then the linear scar will be less visible after hair growth. Anyway, there is no exactly wound edge (upper, lower or both) that recommended for the excellent cosmetic results without any severe side effects. Therefore, this study was designed to determine which is the best trichophytic closure technique.

PROCEDURETrichophytic closure both edge trimming

'Trichophytic closure technique' can be done by trimming upper and lower wound edge for about 0.5 millimeter (as Fig.1) before wound closure. Then the linear scar will be less visible after hair growth. Anyway, there is no exactly wound edge (upper, lower or both) that recommended for the excellent cosmetic results without any severe side effects. Therefore, this study was designed to determine which is the best trichophytic closure technique.

Sponsors

Siriraj Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Male * Age of 25 or more * Diagnosis of androgenetic alopecia * Do not response to conventional treatment and undergo hair transplantation surgery

Exclusion criteria

* Have skin lesion at donor site * Psychological disturbance including trichotillomania * Anti-HIV positive

Design outcomes

Primary

MeasureTime frameDescription
Changing of scar on the donor site during time courses1 week, 4 week, 12 week, 24 week* Hair density * Width of scar * Global photographic view (taken with Cannon 60D 18.0 Megapixels 100 mm macro lens) * Uninvolved dermatologist's assessment \* * Self assessment\*

Secondary

MeasureTime frameDescription
Number of Participants with wound complicationimmediate, 1week, 4week, 12week, 24weekRecord number of patient who have wound problem example Hematoma, Wound separation, wound Infection, etc.

Countries

Thailand

Contacts

Primary ContactRattapon Thuangtong, MD
rattaponthuangtong@yahoo.com+662-419-4333
Backup ContactSaroj Suvanasuthi, MD, PhD
doctorhe@gmail.com+662-419-4333

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026