Evaluation of Hemodynamics and Amount of Blood Flowing Through the Kidneys by Measuring Some Physiological Substances in Blood and Urines

Hemodynamic Indexes and Renal Perfusion: Indirect Evaluation of Blood Volume Using the Association Between ScvO2 and Urinary Electrolytes in Patients Undergoing Major Surgery.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01650103

Enrollment

Registered

2012-07-26

Start date

2012-07-31

Completion date

2015-12-31

Last updated

2014-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypovolemia, Renal Hypoperfusion

Keywords

hypovolemia, renal hypoperfusion, major surgery, sodium, potassium, chloride, ScvO2, hemodynamic indexes

Brief summary

The purpose of this study is to verify any existing relationship between mixed oxygen saturation (from central venous catheter) and urinary sodium, potassium, chloride in determining the volemic state and renal perfusion of patients undergoing major surgical interventions.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* thoracic-abdominal major surgical operations * placing of a central venous catheter and urinary catheter * age 18-75 * ASA class I-III

Exclusion criteria

* age above 75 or under 18 * ASA class IV * trauma, sepsis and/or heart-lung failure * liver transplantation * kidney transplantation * pre-existing renal failure * pregnant patients * patients unable to give their written consent

Design outcomes

Primary

Measure	Time frame
Determination of mixed oxygen saturation in central venous blood (ScvO2) and three urinary electrolytes (sodium, potassium, chloride)	During the stay of the patient in the operating room (in average 6 hours) and the eventual stay in the post-surgery intensive care unit (in average 1 day)

Countries

Italy

Contacts

Primary ContactAndrea Bortolato, M.D.

freeandrea.b@libero.it+393316169933

Backup ContactPaolo Feltracco, M.D.

paolofeltracco@inwind.it+393493410225

Outcome results