What is an Important Change in the Short Physical Performance Battery (SPPB)?

Determining the Minimal Important Difference of the Short Physical Performance Battery and 4m Gait Speed in Chronic Respiratory Disease Patients.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01649193

Enrollment

400

Registered

2012-07-25

Start date

2012-03-31

Completion date

2014-05-31

Last updated

2014-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Diseases, Respiratory Tract Diseases

Keywords

Rehabilitation [E02.831], Exercise [G11.427.394.380], Health Education [I02.233.332], [C08], [C08.381]

Brief summary

The purpose of this study is to determine the important change in the Short Physical Performance Battery (SPPB) when used in patients with lung disease. The SPPB is a simple physical test that measures balance and the functioning of the legs. It has been widely used in healthy elderly populations and predicts hospital admission and the onset of disability. The SPPB has not previously been used in patients with lung disease, and it is not clear what change in this test is considered meaningful and worthwhile by patients or doctors (the minimal clinically important difference: MID). Knowing what the MID for the SPPB will allow researchers and doctors to evaluate the effectiveness of current and new treatments, and to detect improvement or deterioration in the condition of patients.

Interventions

OTHERPulmonary rehabilitation

An eight week out-patient based programme consisting of twice weekly supervised exercise and educational sessions

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* All patients entering pulmonary rehabilitation

Exclusion criteria

* Any patient in whom mobility and lower limb function have been significantly affected by a neuromuscular cause, severe peripheral vascular disease or amputation. * Any patient whom the chief investigator feels it is unsafe to exercise (e.g. unstable cardiac disease).

Design outcomes

Primary

Measure	Time frame
Change from baseline of Short Physical Performance Battery	8 weeks

Secondary

Measure	Time frame
Change from baseline of MRC Dyspnoea Scale	8 weeks
Change from baseline of St George's Respiratory Questionaire	8 weeks
Anchor question (5-point Likert scale)	8 weeks

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 10, 2026