Surgical Site Infection
Conditions
Keywords
staphylococcus aureus, prosthetic joint implantation
Brief summary
This study will evaluate which body site(s) provide the best source of possible staph presence in participants undergoing total joint arthroplasty. If the pre-operative cultures indicate staph presence, an Infectious Disease specialist will be consulted for standard of medical care consultation and treatment management. Participants will be followed for 2 years post-implantation of prosthetic joint to monitor development of prosthetic joint infection.
Detailed description
The presence of Staph in/on a patient who will undergo total joint replacement is a risk in that the patient could go on to develop infection at the surgery site after surgery. The purpose of this study is to evaluate if it is beneficial to to administer a questionnaire and obtain cultures from various body sites from patients prior to surgery and also to determine which body site(s) provide the best source of possible staph presence. If the pre operative cultures indicate staph is present, an Infectious Disease specialist will be consulted for standard of medical care consultation and treatment management. All patients scheduled to have total joint arthroplasty are eligible to participate. The research team will follow the study patients for 2 years after they undergo prosthetic joint implantation to monitor for development of prosthetic joint infection.
Interventions
None listed
Sponsors
University of Nebraska
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* All adult patients undergoing prosthetic joint implantation
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Development of surgical site infection. | Change in surgical site from baseline at 6 months, 1 year, 18 months and 2 years. | The patient will be assessed by phone every 6 months for 2 years for development of infection at the surgical site. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Anatomical site(s) which are best utilized for swab cultures to detect S aureus. | Up to 24 months post operatively. | We hope to determine which anatomical site(s) are best utilized for swab cultures to detect S aureus colonization in patients undergoing prosthetic joint replacement. We will collect data on infection development for up to 2 years post operatively. |
| Post operative infection (s.aureus) development. | Up to 24 months post operation. | We will measure at what percentage a pre-operative questionnaire accurately predicts if a patient will develop an infection (s.aureus) between day one and 2 years post operatively. |
Countries
United States
Outcome results
None listed