Polyp of Large Intestine
Conditions
Brief summary
Most of colorectal polyps founded during colonoscopy are diminutive polyps less than 6 mm. However, complete removal of diminutive polyps is required to prevent tumor recurrence and development of potential interval cancers. Currently, a variety of polypectomy techniques such as hot snare, cold snare, and cold forceps polypectomy are frequently used for the removal of diminutive colorectal polyps. In regard to the completeness of polypectomy, there are few data comparing cold snare polypectomy with cold forceps biopsy technique for removal of diminutive (1-5 mm) colorectal polyps. The aim of this study is to compare cold snare polypectomy with cold forceps polypectomy using double biopsy technique for removal of diminutive colorectal polyps.
Interventions
PROCEDUREremoval of eligible polyps using cold snare polypectomy technique
Snare polypectomy using a mini (10 mm open diameter) size electrosurgical snare without application of electrocautery
PROCEDUREremoval of eligible polyps using double biopsy technique
Cold forceps polypectomy using a standard- capacity forceps with double biopsy technique (two bites per one forceps pass)
Sponsors
Kyunghee University Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients over the age of 20 * Informed consent
Exclusion criteria
* Patient undergoing antiplatelets (aspirin, clopidogrel and others) or anticoagulant therapy * Known existing bleeding tendency (thrombocytopenia or prolonged INR) * Inflammatory bowel diseases (Crohn's disease, or ulcerative colitis) * ASA class III or more * Pregnancy * Any condition which, in the opinion of the Investigator, places the patient at unacceptable risk if he/she were to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete histologic polyp eradication rate | 2 weeks |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Time taken for polypectomy (complete visual eradication of each polyp) | 2 weeks | time from polyp resection to tissue retrieval |
| Successful tissue retrieval rate of removed tissues | 2 weeks | — |
| Rates of adverse events | 4 weeks | Adverse events include postpolypectomy bleeding and others (polypectomy syndrome or perforation). |
| Complete visual polyp eradication rate | 2 weeks | — |
Countries
South Korea
Outcome results
None listed