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Could Non-invasive Biochemical, Image or Physiological Index Predict Significant Coronary Arterial Stenosis in Symptomatic Adults?

Could Non-invasive Biochemical, Image or Physiological Index Predict Significant Coronary Arterial Stenosis in Symptomatic Adults?

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01645228
Enrollment
120
Registered
2012-07-20
Start date
2012-08-31
Completion date
2013-07-31
Last updated
2012-08-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Heart Disease

Brief summary

To validate the capability of non-invasive bio-image tests in prediction of significant coronary stenosis of symptomatic adults.

Detailed description

The main objective is to validate the capability of these non-invasive tests (CCS, hs-CRP and ABI) in prediction of significant coronary stenosis of symptomatic adults. The end-point will be the findings of coronary CT angiography. The investigators hope the results of our study could be applied on the interpretation of health examination and the advice of follow-up and therapy.

Interventions

RADIATIONcoronary calcium score measurement
BIOLOGICALhigh sensitivity C reactive protein measurement
PROCEDUREankle brachial index measurement

Sponsors

National Science and Technology Council, Taiwan
CollaboratorOTHER_GOV
Cathay General Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
30 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* subjects for a general health check-up protocol, which included CACS and CCTA, and biochemical measurements (total cholesterol, total triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, high sensitivity C reactive protein)

Exclusion criteria

* anyone allergy to iodine contrast medium, unable cooperation for CT scanning, asymptomatic

Design outcomes

Primary

MeasureTime frame
coronary CT angiographywithin one month

Countries

Taiwan

Contacts

Primary ContactYuan Heng Mo, MD
jamesmyh@yahoo.com.tw886-2-27082121

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026