Effects of Forms of Modified CIT on Upper Extremity Performance in Cerebral Palsy

Effects of Forms of Modified Constraint-induced Therapy on Functional Performance of Upper Extremity in Children With Cerebral Palsy With Asymmetric Motor Impairments: A Follow up Study of Kinematic and Clinical Analyses

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01643239

Enrollment

Registered

2012-07-18

Start date

1996-08-31

Completion date

Unknown

Last updated

2013-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral Palsy

Keywords

Modified constraint-induced therapy, Children with cerebral palsy, Kinematic analysis, Group therapy

Brief summary

The purpose of this study will employ clinical assessment tools to examine the effects of modified constraint-induced therapy (mCIT) on the more affected upper extremity of children with cerebral palsy.

Detailed description

The study included threefold: (1) It will employ kinematic analysis, along with clinical assessment tools to examine the effects of mCIT on the more affected upper extremity of children with cerebral palsy with asymmetric motor impairments after treatment immediately and 1 year following. The clinical tools will include Motor Activity Log (MAL), Bruininks-Oseretsky Test of Motor Proficiency (BOTMP),Peabody-Developmental Motor Scales (PDMS-II), and Wee-FIM. (2) This study looked at the intervention impact on bimanual coordination and the less affected upper extremity. (3) It investigated the effects of forms (group vs. individual intervention) on upper extremity performance.

Interventions

OTHERHospital-based mCIT restraint of the unaffected arm and practice of the affected arm

the mCIT group with individualized intervention

OTHERHospital-based mCIT

the mCIT group with individualized intervention

OTHERHospital-based TR

OT or PT or therapist-based training

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

ALL

Age

4 Years to 10 Years

Healthy volunteers

Inclusion criteria

1. clinical diagnosis of spastic CP 2. age between 4 and 10 years old 3. shoulder flexion of the affected upper limb more than 90 degrees, elbow extension over 160 degrees, wrist extension to 10 degrees at least, and fingers full flexion to 10 degrees at least 4. basic balance ability: sitting on the chair without arm support; feet stay on the floor consistently; performing the affected upper limb movement without losing balance 5. ability to follow simple oral commands 6. no related musculoskeletal surgery of the affected upper limb 7. not have injected the Botox into the affected upper extremity during the past 6 months 8. no visual or auditory disability

Design outcomes

Primary

Measure	Time frame	Description
Kinematic assessment	up to six years	An analysis program coded by LabVIEW (National Instruments, Inc., Austin, TX) language was used to process the kinematic data. The variables of reaction time (sec), normalized movement time (sec/mm), normalized total displacement (unit), joint ranges recruitment (normalized shoulder flexion angle, normalized elbow flexion; degree/mm) angle, and normalized maximum shoulder abduction angle), and maximum shoulder and elbow cross correlation were collected.

Secondary

Measure	Time frame	Description
Clinical measures at the motor quality and performance include Motor Activity Log (MAL), Bruininks-Oseretsky Test of Motor Proficiency (BOTMP), and Peabody-Developmental Motor Scales (PDMS-II)	up to six years	The clinical tools used in this study measure the intervention impact on bimanual coordination and unilateral performance of upper extremity.

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026