Human Immunodeficiency Virus
Conditions
Keywords
HIV, fructose
Brief summary
The goal of this research is the attempt to implement a new research method based on modern electrochemistry successes, in particular the development of the polarographic method of fructose and fructose diphosphate identification and its implementation to detect the viral infection in early stage. There will be 20 samples from the HIV-infected patients and 30 samples from the heath controls. The study will collect 10ml urine and examined fructose and fructose-diphosphate using the polarographic method.
Detailed description
The goal of this research is the attempt to implement a new research method based on modern electrochemistry successes, in particular the development of the polarographic method of fructose and fructose diphosphate identification and its implementation to detect the viral infection in early stage.
Interventions
None listed
Sponsors
Kaohsiung Medical University Chung-Ho Memorial Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* HIV infection
Exclusion criteria
* who are in highly active antiretroviral therapy(HARRT) therapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Fructose Identification in Urine to Detect the Viral Infection : Number of Participants With Positive and Negative Waveform | Participants provided urine samples once | This detection technique, after a viral infection caused by the use of cell pathological changes and urine metabolic waste - fructose concentration, derivatives.Health News voltage changes to detect viral pathogens of activity and virulence. Because viral infection caused by the voltage change has its typical, So you can use voltage measurements to calibrate the presence and activity of a viral infection. 1.How to interpretation the data The gap between values on X-axis is σ, and 50 is a reference to the center position. For example, the sample maybe contain with HIV virus if σ≧10 units. σ≧10 abnormal positive (+) σ\<10 normal negative (-) |
Countries
Taiwan
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| HIV Infected Patients The people had infected HIV | 20 |
| Healthy Controls The people didn't have infected HIV | 30 |
| Total | 50 |
Baseline characteristics
| Characteristic | Healthy Controls | HIV Infected Patients | Total |
|---|---|---|---|
| Age, Categorical <=18 years | 0 Participants | 0 Participants | 0 Participants |
| Age, Categorical >=65 years | 0 Participants | 0 Participants | 0 Participants |
| Age, Categorical Between 18 and 65 years | 30 Participants | 20 Participants | 50 Participants |
| Age, Continuous | 31.87 years STANDARD_DEVIATION 9.46 | 33.15 years STANDARD_DEVIATION 10.27 | 32.38 years STANDARD_DEVIATION 9.71 |
| Region of Enrollment Taiwan | 30 participants | 20 participants | 50 participants |
| Sex: Female, Male Female | 18 Participants | 1 Participants | 19 Participants |
| Sex: Female, Male Male | 12 Participants | 19 Participants | 31 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk |
|---|---|---|
| deaths Total, all-cause mortality | — / — | — / — |
| other Total, other adverse events | 0 / 0 | 0 / 0 |
| serious Total, serious adverse events | 0 / 0 | 0 / 0 |
Outcome results
Primary
Fructose Identification in Urine to Detect the Viral Infection : Number of Participants With Positive and Negative Waveform
This detection technique, after a viral infection caused by the use of cell pathological changes and urine metabolic waste - fructose concentration, derivatives.Health News voltage changes to detect viral pathogens of activity and virulence. Because viral infection caused by the voltage change has its typical, So you can use voltage measurements to calibrate the presence and activity of a viral infection. 1.How to interpretation the data The gap between values on X-axis is σ, and 50 is a reference to the center position. For example, the sample maybe contain with HIV virus if σ≧10 units. σ≧10 abnormal positive (+) σ\<10 normal negative (-)
Time frame: Participants provided urine samples once
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| HIV Infected Patients | Fructose Identification in Urine to Detect the Viral Infection : Number of Participants With Positive and Negative Waveform | Positive in waveform | 12 participants |
| HIV Infected Patients | Fructose Identification in Urine to Detect the Viral Infection : Number of Participants With Positive and Negative Waveform | Negative in waveform | 8 participants |
| Healthy Controls | Fructose Identification in Urine to Detect the Viral Infection : Number of Participants With Positive and Negative Waveform | Positive in waveform | 7 participants |
| Healthy Controls | Fructose Identification in Urine to Detect the Viral Infection : Number of Participants With Positive and Negative Waveform | Negative in waveform | 23 participants |