Cow Milk Allergy
Conditions
Keywords
cow milk allergy, amino acid formula
Brief summary
The purpose of this study is to determine growth and protein status of infants with cow's milk protein allergy and treated with a newly innovated amino acid formula compared to those with a commercial amino acid formula.
Detailed description
Severe cases of cow's milk protein allergy are treated with the amino acid formula. The amino acid formula is composed of essential and non-essential amino acids, vegetable oils with or without MCT oil, and glucose polymer from various carbohydrate sources. Such formula is also fortified by minerals, trace elements,and vitamins.
Interventions
DIETARY_SUPPLEMENTComparison of treatment with different amino acid formulas
Growth and amino acid status of a newly innovated amino acid formula (NAAF) and a commercial amino acid formula (AAF)
Sponsors
Mahidol University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Weeks to 6 Months
Healthy volunteers
Yes
Inclusion criteria
* Singleton * Clinical diagnosis of cow's milk protein allergy
Exclusion criteria
* Other diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Growth and protein status | 4 weeks | * compare body weight, length, head circumference, triceps skin fold thickness, mid-arm circumference, and arm muscle area between NAAF and AAF groups * compare plasma amino acids, serum albumin, blood urea nitrogen, and creatinine between NAAF and AAF groups |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Growth | 4 weeks | * compare weight, length, head circumference, triceps skin fold thickness, mid-arm circumference, and arm muscle area between either NAAF group or AAF group and normal infants fed with either breast milk or infant formula. * compare plasma amino acids between either NAAF group or AAF group and normal published data |
Countries
Thailand
Outcome results
None listed