Lung Cancer
Conditions
Keywords
Lung cancer
Brief summary
A continuous loss of moisture and heat occurs during mechanical ventilation and prediposes patients to airway damage. Vaporizing humidifier has known to be advantages of improvement of oxygenation and protection of airway damage. However, there is a lack of study about the effect of humidified ventilation on oxygenation and respiratory mechanics during one-lung ventilation. We therefore invesgate that the effect of humidified ventilation on oxygenation and respiratory mechanics during one-lung ventilation .
Interventions
PROCEDUREVaporizing humidifier
Vaporizing humidifier applying during one-lung ventilation
Sponsors
Yonsei University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
30 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* ASA physical status class I,II * Unilateral lung lobectomy * Use of one-lung ventilation
Exclusion criteria
* COPD * CAOD * Unstable cardiovascular status * Peak inspiratory pressure \> 30 mmHg
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| arterial oxygenation | T1(10min before one-lung ventilation),T2(30min after one-lung ventilation),T3(60min), T4(10min after two lung ventilation) | T1,T2,T3,T4: all measurement in lateral position, T1-arterial oxygenation(PaO2), T2-arterial oxygenation(PaO2),T3-arterial oxygenation(PaO2),T4-arterial oxygenation(PaO2) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Respiratory dynamic parameters | T1,T2,T3,T4 (same as 'primary outcome measure') | T1,T2,T3,T4: T1-respiratory dynamic parameters, T2-respiratory dynamic parameters, T3-respiratory dynamic parameters, T4-respiratory dynamic parameters |
Countries
South Korea
Outcome results
None listed