Effects of Oropharyngeal Exercises on Patients With Primary Snore, Mild and Moderate Obstructive

Effects of Oropharyngeal Exercises on Snoring Intensity, Symptoms, Upper Airway Anatomy and Collapsability of Upper Airway Awake and Asleep in Patients With Primary Snoring and Mild to Moderate Obstructive Sleep Apnea

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01636856

Acronym

EOE

Enrollment

Registered

2012-07-10

Start date

2011-12-31

Completion date

2015-12-31

Last updated

2014-05-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Snore, Obstructive Sleep Apnea (Mild and Moderate).

Keywords

oropharyngeal exercises, obstructive sleep apnea, speech therapy, magnetic resonance, PCRIT, negative expiratory pressure, snore

Brief summary

Randomized study of patients with primary snore, mild and moderate obstructive sleep apnea. Protocol include 40 patients randomized to oropharyngeal exercise or use of nasal dilator, breathing exercise and nasal lavage. The objectives are study the effects of therapy on oropharyngeal in a series of clinical and physiologic and anatomic variables, changes on snore and quality of sleep using Pharyngeal Critical Pressure, Magnetic Resonance, Negative expiratory pressure and snore analyses. Hypothesis that the therapy group (oropharyngeal exercises) will have more modifications compared to the control group.

Detailed description

This is randomized study with multiple primary endpoints. In December 2012 the study also started collecting tongue strength and endurance (IOPI). Because not all patients are able to perform all evaluations, the publications will be divided and presented according to the completion of the required number of patients for each primary endpoint.

Interventions

BEHAVIORALOropharyngeal exercises

Oropharyngeal exercises (derived from speech language pathology) to the soft palate, tongue and facial muscles exercises as well as stomatognathic functions.

BEHAVIORALRespiratory exercises, nasal dilator, nasal lavage

Respiratory exercises, nasal dilator, nasal lavage

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

25 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

subjects with primary snore, mild and moderate obstructive sleep apnea

Exclusion criteria

BMI \> or = 40, craniofacial malformations, smokers, pregnant women, edentulous, total dental prostheses, use of hypnotic medications, stroke, neuromuscular dystrophy, coronary artery disease, chronic heart failure, chronic obstructive pulmonary disease, severe nasal obstructive disease, pharyngeal surgery,already made some kind of treatment for obstructive sleep apnea.

Design outcomes

Primary

Measure	Time frame
Snore	3 months
Upper airway collapsability	3 months
Images from magnetic resonance	3 months
Negative expiratory pressure	3 months

Secondary

Measure	Time frame
Sleep related questionnaires	3 months

Countries

Brazil

Contacts

Primary ContactGeraldo Lorenzi-Filho, MD, PhD

geraldo.lorenzi@incor.usp.br55-XX-11-26615486

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 15, 2026