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Comparison of Muscle Atrophy After Direct Anterior & Posterior Total Hip Arthroplasty

The Influence of Operative Approach on Muscle Atrophy After Total Hip Arthroplasty: A Comparison of Anterior and Posterior Approaches

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01636375
Enrollment
19
Registered
2012-07-10
Start date
2012-05-31
Completion date
2021-07-31
Last updated
2021-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis, Hip

Brief summary

This project is designed to use MRI to evaluate pre- and post-arthroplasty hips; the specific aims of this project are three-fold. First, the investigators intend to compare the amount of muscle atrophy and tendon damage that occurs around the hip between two commonly-used operative approaches: the direct-anterior approach and the posterior approach. Second, the investigators aim to provide baseline data on the amount of muscle atrophy and tendon damage that should reasonably be expected to occur with both of these approaches. Third, the investigators will document the degree of recovery of the periprosthetic soft tissues post-surgery in both patient groups. The investigators first hypothesis is that the posterior approach will demonstrate significantly more damage to the abductors, piriformis, and short external rotators than the direct anterior approach, which will demonstrate minimal soft tissue damage. The investigators second hypothesis is that both surgical approaches will cause some degree of baseline muscle damage and atrophy, in a predictable pattern. The investigators third hypothesis is that each of the surgical approaches inherently cause some degree of soft tissue damage, and that the periprosthetic soft tissues that are incised during the surgical exposure will recover in a predictable pattern which is consistent but unique within each group

Interventions

None listed

Sponsors

Northwell Health
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

1. Patients undergoing elective, primary total hip arthroplasty 2. Use of Cementless Total Hip components 3. Preoperative diagnosis of degenerative joint disease secondary to osteoarthritis

Exclusion criteria

1. Prior surgery on the affected hip 2. No implanted medical devices or metallic debris in the patient which will preclude use of MRI 3. patients must be able to participate in standard post-arthroplasty rehabilitation protocols.

Design outcomes

Primary

MeasureTime frameDescription
Change from baseline in muscle volume at 6 weeks6 weeks after surgeryMuscle volume will be recorded in MRI images with specialized software (external rotators,tensor fascia lata, rectus femoris,gluteus medius and minimus)
Change from baseline in muscle volume at 6 months6 months after surgery

Secondary

MeasureTime frameDescription
Change in Fatty atrophy of muscles from baseline at 6weeks6 weeks after surgeryQualitative assessment of fatty atrophy
tendon damage6 weeks after surgeryQualitative assessment of tendon damage on MRI
Change in fatty atrophy of muscles from baseline at 6 months6 months after surgery
Tendon damage6 months after surgery

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026