Sleep Apnea, Obstructive
Conditions
Keywords
DNA oxidation, obstructive sleep apnea, lipid peroxidation, oxidative stresses
Brief summary
The purpose of this study is to determine the possible effects of uvulopalatopharngoplasty (UPPP) -which is a a therapy used on patients with Obstructive sleep apnea syndrome (OSAS- on oxidative damage.
Detailed description
Obstructive sleep apnea syndrome (OSAS) is a sydrome which has characteristic upper way obstruction and a decrease in blood oxygen saturation as sleeping. uvulopalatopharngoplasty (UPPP)is one of the surgical approaches applied to the patients with OSAS, since the oxidative damage markers have been found high in patients with OSAS. Although antioxidant levels were higher in patients with OSAS than those in normal population, there is report about the effect of UPPP on antioxidant status in patients with OSAS. We performed this study to confirm whether is there a We performed the present study to confirm whether there is a relationship between the OSAS and oxidative damage before and after UPPP.
Interventions
None listed
Sponsors
Study design
Eligibility
Inclusion criteria
* Patients who underwent uvulopalatopharngoplasty (UPPP)for Obstructive sleep apnea syndrome (OSAS)
Exclusion criteria
* Anormal nasopharyngeal computed tomography, chronic diseases such as diabetes mellitus, hypertension etc.
Countries
Turkey (Türkiye)