Pediatric Radio Frequency Coils Generic

Pediatric Radio Frequency Coil Development on Clinical and Research MR Scanners

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01633866

Enrollment

Registered

2012-07-04

Start date

2012-07-01

Completion date

2031-06-01

Last updated

2026-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Duchenne Muscular Dystrophy, Musculoskeletal Abnormalities

Keywords

Magnetic Resonance Imaging

Brief summary

The purpose of this study is to evaluate and optimize advances in radio frequency (RF) coil magnetic resonance imaging (MRI) technology at Cincinnati Children's Hospital Medical Center (CCHMC).

Detailed description

Pediatric Magnetic resonance (MR) imaging techniques have been limited by the unavailability of specialized radio-frequency (RF) coils for pediatric imaging. Typically, MR coils are designed for general purpose adult imaging and lack the mechanical design, flexibility and high channel count needed for pediatric imaging. Furthermore, pediatric patients are often positioned decubitus or prone rather than supine. This makes coil positioning even more challenging and often results in images with low SNR and poor image quality. Many coils used in clinical practice have fixed dimensions that do not fit within the realm of "one-size fits all," especially for the huge variation found in the pediatric patient population. MRI coil development and optimization is performed by MR manufacturers and in research laboratories across the world including the Imaging Research Center (IRC) of Cincinnati Children's Hospital and Medical Center (CCHMC). Coil development and refinement involves evaluating the new coils on inert phantoms and then imaging examinations performed on healthy participants and patients. The focus of this study protocol is to evaluate the design and performance of investigational coils on patients and healthy participants.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

Healthy participants: * Male or Female * Thermally stable * Any age Clinical patients: * Male or Female * Thermally stable * any age

Exclusion criteria

Healthy participants \& Clinical patients * Female participants who are pregnant or lactating * Subjects iwth standard contraindications to MRI

Design outcomes

Primary

Measure	Time frame
Number of participants with adverse events as measured by heating and comfort participant response	Day 1

Secondary

Measure	Time frame
MRI Image Quality	2 Weeks Post MRI Scan

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORCharles Dumoulin, PhD

Children's Hospital Medical Center, Cincinnati

Outcome results